Quantitative comparison of DNA methylation assays for biomarker development and clinical applications
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Published in Nature biotechnology (01.07.2016)
Published in Nature biotechnology (01.07.2016)
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Noninvasive detection of fetal trisomy 21 by sequencing of DNA in maternal blood: a study in a clinical setting
Ehrich, Mathias, MD, Deciu, Cosmin, MSc, Zwiefelhofer, Tricia, Tynan, John A., DPhil, Cagasan, Lesley, MSc, Tim, Roger, DPhil, Lu, Vivian, McCullough, Ron, DPhil, McCarthy, Erin, Nygren, Anders O.H., DPhil, Dean, Jarrod, Tang, Lin, DPhil, Hutchison, Don, MSc, Lu, Tim, DPhil, Wang, Huiquan, DPhil, Angkachatchai, Vach, DPhil, Oeth, Paul, MSc, Cantor, Charles R., DPhil, Bombard, Allan, MD, van den Boom, Dirk, DPhil
Published in American journal of obstetrics and gynecology (01.03.2011)
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High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs
Rottenberg, Sven, Jaspers, Janneke E, Kersbergen, Ariena, van der Burg, Eline, Nygren, Anders O.H, Zander, Serge A.L, Derksen, Patrick W.B, de Bruin, Michiel, Zevenhoven, John, Lau, Alan, Boulter, Robert, Cranston, Aaron, O'Connor, Mark J, Martin, Niall M.B, Borst, Piet, Jonkers, Jos
Published in Proceedings of the National Academy of Sciences - PNAS (04.11.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (04.11.2008)
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Multiplex Ligation-Dependent Probe Amplification Technique for Copy Number Analysis on Small Amounts of DNA Material
Sørensen, Karina Meden, Andersen, Paal Skytt, Larsen, Lars Allan, Schwartz, Marianne, Schouten, Jan P, Nygren, Anders O. H
Published in Analytical chemistry (Washington) (01.12.2008)
Published in Analytical chemistry (Washington) (01.12.2008)
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Moderate Increase in Mdr1a/1b Expression Causes In vivo Resistance to Doxorubicin in a Mouse Model for Hereditary Breast Cancer
PAJIC, Marina, IYER, Jayasree K, KERSBERGEN, Ariena, VAN DER BURG, Eline, NYGREN, Anders O. H, JONKERS, Jos, BORST, Piet, ROTTENBERG, Sven
Published in Cancer research (Chicago, Ill.) (15.08.2009)
Published in Cancer research (Chicago, Ill.) (15.08.2009)
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Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer
Rottenberg, Sven, Nygren, Anders O.H, Pajic, Marina, van Leeuwen, Fijs W.B, van der Heijden, Ingrid, van de Wetering, Koen, Liu, Xiaoling, de Visser, Karin E, Gilhuijs, Kenneth G, van Tellingen, Olaf, Schouten, Jan P, Jonkers, Jos, Borst, Piet
Published in Proceedings of the National Academy of Sciences - PNAS (17.07.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (17.07.2007)
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Poly(ADP-Ribose) Polymerase-1 Inhibitor Treatment Regresses Autochthonous Brca2/p53-Mutant Mammary Tumors In vivo and Delays Tumor Relapse in Combination with Carboplatin
HAY, Trevor, MATTHEW, James R, CLARKE, Alan R, PIETZKA, Lucie, LAU, Alan, CRANSTON, Aaron, NYGREN, Anders O. H, DOUGLAS-JONES, Anthony, SMITH, Graeme C. M, MARTIN, Niall M. B, O'CONNOR, Mark
Published in Cancer research (Chicago, Ill.) (01.05.2009)
Published in Cancer research (Chicago, Ill.) (01.05.2009)
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Sensitivity and Acquired Resistance of BRCA1 ;p53-Deficient Mouse Mammary Tumors to the Topoisomerase I Inhibitor Topotecan
ZANDER, Serge A. L, KERSBERGEN, Ariena, BORST, Piet, ROTTENBERG, Sven, VAN DER BURG, Eline, DE WATER, Niels, VAN TELLINGEN, Olaf, GUNNARSDOTTIR, Sjöfn, JASPERS, Janneke E, PAJIC, Marina, NYGREN, Anders O. H, JONKERS, Jos
Published in Cancer research (Chicago, Ill.) (15.02.2010)
Published in Cancer research (Chicago, Ill.) (15.02.2010)
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Methylation-Specific MLPA (MS-MLPA): simultaneous detection of CpG methylation and copy number changes of up to 40 sequences
Nygren, Anders O. H., Ameziane, Najim, Duarte, Helena M. B., Vijzelaar, Raymon N. C. P., Waisfisz, Quinten, Hess, Corine J., Schouten, Jan P., Errami, Abdellatif
Published in Nucleic acids research (01.01.2005)
Published in Nucleic acids research (01.01.2005)
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REEP1 mutation spectrum and genotype/phenotype correlation in hereditary spastic paraplegia type 31
Beetz, Christian, Schüle, Rebecca, Deconinck, Tine, Tran-Viet, Khanh-Nhat, Zhu, Hui, Kremer, Berry P.H., Frints, Suzanna G.M., van Zelst-Stams, Wendy A.G., Byrne, Paula, Otto, Susanne, Nygren, Anders O.H., Baets, Jonathan, Smets, Katrien, Ceulemans, Berten, Dan, Bernard, Nagan, Narasimhan, Kassubek, Jan, Klimpe, Sven, Klopstock, Thomas, Stolze, Henning, Smeets, Hubert J.M., Schrander-Stumpel, Constance T.R.M., Hutchinson, Michael, van de Warrenburg, Bart P., Braastad, Corey, Deufel, Thomas, Pericak-Vance, Margaret, Schöls, Ludger, de Jonghe, Peter, Züchner, Stephan
Published in Brain (London, England : 1878) (01.04.2008)
Published in Brain (London, England : 1878) (01.04.2008)
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High-resolution mapping of the 8p23.1 beta-defensin cluster reveals strictly concordant copy number variation of all genes
Groth, Marco, Szafranski, Karol, Taudien, Stefan, Huse, Klaus, Mueller, Oliver, Rosenstiel, Philip, Nygren, Anders O.H, Schreiber, Stefan, Birkenmeier, Gerd, Platzer, Matthias
Published in Human mutation (01.10.2008)
Published in Human mutation (01.10.2008)
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A multi-exonic SPG4 duplication underlies sex-dependent penetrance of hereditary spastic paraplegia in a large Brazilian pedigree
MITNE, Miguel, KOK, Fernando, NYGREN, Anders O. H, VALADARES, Marcos, CERQUEIRA, Antonia M. P, STARLING, Alessandra, DEUFEL, Thomas, ZATZ, Mayana, BEETZ, Christian, PESSOA, André, BUENO, Clarissa, GRACIANI, Zodja, MARTYN, Marcilia, MONTEIRO, Carlos B. M, MITNE, Guilherme, HUBERT, Paulo
Published in European journal of human genetics : EJHG (01.12.2007)
Published in European journal of human genetics : EJHG (01.12.2007)
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Rapid and reliable detection of exon rearrangements in various movement disorders genes by multiplex ligation-dependent probe amplification
Djarmati, Ana, Gužvić, Miodrag, Grünewald, Anne, Lang, Anthony E., Pramstaller, Peter P., Simon, David K., Kaindl, Angela M., Vieregge, Peter, Nygren, Anders O. H., Beetz, Christian, Hedrich, Katja, Klein, Christine
Published in Movement disorders (15.09.2007)
Published in Movement disorders (15.09.2007)
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Ultrasensitive Detection of Multiplexed Somatic Mutations Using MALDI-TOF Mass Spectrometry
Mosko, Michael J, Nakorchevsky, Aleksey A, Flores, Eunice, Metzler, Heath, Ehrich, Mathias, van den Boom, Dirk J, Sherwood, James L, Nygren, Anders O.H
Published in The Journal of molecular diagnostics : JMD (2016)
Published in The Journal of molecular diagnostics : JMD (2016)
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Mechanistic basis of an epistatic interaction reducing age at onset in hereditary spastic paraplegia
Newton, Timothy, Allison, Rachel, Edgar, James R, Lumb, Jennifer H, Rodger, Catherine E, Manna, Paul T, Rizo, Tania, Kohl, Zacharias, Nygren, Anders O H, Arning, Larissa, Schüle, Rebecca, Depienne, Christel, Goldberg, Lisa, Frahm, Christiane, Stevanin, Giovanni, Durr, Alexandra, Schöls, Ludger, Winner, Beate, Beetz, Christian, Reid, Evan
Published in Brain (London, England : 1878) (01.05.2018)
Published in Brain (London, England : 1878) (01.05.2018)
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Low proportion of whole exon deletions causing phenylketonuria in Denmark and Germany
Birk Møller, Lisbeth, Nygren, Anders O.H., Scott, Patrick, Hougaard, Pia, Bieber Nielsen, Jytte, Hartmann, Caroline, Güttler, Flemming, Tyfield, Linda, Zschocke, Johannes
Published in Human mutation (01.02.2007)
Published in Human mutation (01.02.2007)
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Cri du Chat Syndrome and Primary Ciliary Dyskinesia: A Common Genetic Cause on Chromosome 5p
Shapiro, Adam J., MD, Weck, Karen E., MD, Chao, Kay C., MS, PhD, Rosenfeld, Margaret, MD, MPH, Nygren, Anders O.H., MSc, PhD, Knowles, Michael R., MD, Leigh, Margaret W., MD, Zariwala, Maimoona A., MSc, PhD
Published in The Journal of pediatrics (01.10.2014)
Published in The Journal of pediatrics (01.10.2014)
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