Regulation of NOD‐like receptors and inflammasome activation in cerebral endothelial cells
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Published in Journal of neurochemistry (01.11.2015)
Published in Journal of neurochemistry (01.11.2015)
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Endothelial deficiency of insulin‐like growth factor‐1 receptor leads to blood–brain barrier disruption and accelerated endothelial senescence in mice, mimicking aspects of the brain aging phenotype
Gulej, Rafal, Csik, Boglarka, Faakye, Janet, Tarantini, Stefano, Shanmugarama, Santny, Chandragiri, Siva Sai, Mukli, Peter, Conley, Shannon, Csiszar, Anna, Ungvari, Zoltan, Yabluchanskiy, Andriy, Nyúl‐Tóth, Ádám
Published in Microcirculation (New York, N.Y. 1994) (01.02.2024)
Published in Microcirculation (New York, N.Y. 1994) (01.02.2024)
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Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses
Csipo, Tamas, Lipecz, Agnes, Owens, Cameron, Mukli, Peter, Perry, Jonathan W., Tarantini, Stefano, Balasubramanian, Priya, Nyúl-Tóth, Ádám, Yabluchanska, Valeriya, Sorond, Farzaneh A., Kellawan, J. Mikhail, Purebl, György, Sonntag, William E., Csiszar, Anna, Ungvari, Zoltan, Yabluchanskiy, Andriy
Published in Scientific reports (25.10.2021)
Published in Scientific reports (25.10.2021)
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Paracellular and transcellular migration of metastatic cells through the cerebral endothelium
Herman, Hildegard, Fazakas, Csilla, Haskó, János, Molnár, Kinga, Mészáros, Ádám, Nyúl‐Tóth, Ádám, Szabó, Gábor, Erdélyi, Ferenc, Ardelean, Aurel, Hermenean, Anca, Krizbai, István A., Wilhelm, Imola
Published in Journal of cellular and molecular medicine (01.04.2019)
Published in Journal of cellular and molecular medicine (01.04.2019)
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Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects
Kiss, Tamas, Nyúl-Tóth, Ádám, Balasubramanian, Priya, Tarantini, Stefano, Ahire, Chetan, Yabluchanskiy, Andriy, Csipo, Tamas, Farkas, Eszter, Wren, Jonathan D., Garman, Lori, Csiszar, Anna, Ungvari, Zoltan
Published in GeroScience (01.04.2020)
Published in GeroScience (01.04.2020)
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Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain
Kiss, Tamas, Nyúl-Tóth, Ádám, Balasubramanian, Priya, Tarantini, Stefano, Ahire, Chetan, DelFavero, Jordan, Yabluchanskiy, Andriy, Csipo, Tamas, Farkas, Eszter, Wiley, Graham, Garman, Lori, Csiszar, Anna, Ungvari, Zoltan
Published in GeroScience (01.04.2020)
Published in GeroScience (01.04.2020)
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Pericyte‐secreted IGF2 promotes breast cancer brain metastasis formation
Molnár, Kinga, Mészáros, Ádám, Fazakas, Csilla, Kozma, Mihály, Győri, Fanni, Reisz, Zita, Tiszlavicz, László, Farkas, Attila E., Nyúl‐Tóth, Ádám, Haskó, János, Krizbai, István A., Wilhelm, Imola
Published in Molecular oncology (01.09.2020)
Published in Molecular oncology (01.09.2020)
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Nrf2 dysfunction and impaired cellular resilience to oxidative stressors in the aged vasculature: from increased cellular senescence to the pathogenesis of age-related vascular diseases
Ungvari, Zoltan, Tarantini, Stefano, Nyúl-Tóth, Ádám, Kiss, Tamas, Yabluchanskiy, Andriy, Csipo, Tamas, Balasubramanian, Priya, Lipecz, Agnes, Benyo, Zoltan, Csiszar, Anna
Published in GeroScience (01.12.2019)
Published in GeroScience (01.12.2019)
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Treatment with the BCL-2/BCL-xL inhibitor senolytic drug ABT263/Navitoclax improves functional hyperemia in aged mice
Tarantini, Stefano, Balasubramanian, Priya, Delfavero, Jordan, Csipo, Tamas, Yabluchanskiy, Andriy, Kiss, Tamas, Nyúl-Tóth, Ádám, Mukli, Peter, Toth, Peter, Ahire, Chetan, Ungvari, Anna, Benyo, Zoltan, Csiszar, Anna, Ungvari, Zoltan
Published in GeroScience (01.10.2021)
Published in GeroScience (01.10.2021)
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Circulating anti-geronic factors from heterochonic parabionts promote vascular rejuvenation in aged mice: transcriptional footprint of mitochondrial protection, attenuation of oxidative stress, and rescue of endothelial function by young blood
Kiss, Tamas, Tarantini, Stefano, Csipo, Tamas, Balasubramanian, Priya, Nyúl-Tóth, Ádám, Yabluchanskiy, Andriy, Wren, Jonathan D., Garman, Lori, Huffman, Derek M., Csiszar, Anna, Ungvari, Zoltan
Published in GeroScience (01.04.2020)
Published in GeroScience (01.04.2020)
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PEGylation of Reduced Graphene Oxide Induces Toxicity in Cells of the Blood–Brain Barrier: An in Vitro and in Vivo Study
Mendonça, Monique Culturato Padilha, Soares, Edilene Siqueira, de Jesus, Marcelo Bispo, Ceragioli, Helder José, Batista, Ângela Giovana, Nyúl-Tóth, Ádám, Molnár, Judit, Wilhelm, Imola, Maróstica, Mário Roberto, Krizbai, István, da Cruz-Höfling, Maria Alice
Published in Molecular pharmaceutics (07.11.2016)
Published in Molecular pharmaceutics (07.11.2016)
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Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype
Tarantini, Stefano, Nyúl-Tóth, Ádám, Yabluchanskiy, Andriy, Csipo, Tamas, Mukli, Peter, Balasubramanian, Priya, Ungvari, Anna, Toth, Peter, Benyo, Zoltan, Sonntag, William E., Ungvari, Zoltan, Csiszar, Anna
Published in GeroScience (01.10.2021)
Published in GeroScience (01.10.2021)
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Neurovascular Inflammaging in Health and Disease
Mészáros, Ádám, Molnár, Kinga, Nógrádi, Bernát, Hernádi, Zsófia, Nyúl-Tóth, Ádám, Wilhelm, Imola, Krizbai, István A
Published in Cells (Basel, Switzerland) (04.07.2020)
Published in Cells (Basel, Switzerland) (04.07.2020)
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Spatial transcriptomic analysis reveals inflammatory foci defined by senescent cells in the white matter, hippocampi and cortical grey matter in the aged mouse brain
Kiss, Tamas, Nyúl-Tóth, Ádám, DelFavero, Jordan, Balasubramanian, Priya, Tarantini, Stefano, Faakye, Janet, Gulej, Rafal, Ahire, Chetan, Ungvari, Anna, Yabluchanskiy, Andriy, Wiley, Graham, Garman, Lori, Ungvari, Zoltan, Csiszar, Anna
Published in GeroScience (01.04.2022)
Published in GeroScience (01.04.2022)
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IGF1R signaling regulates astrocyte-mediated neurovascular coupling in mice: implications for brain aging
Tarantini, Stefano, Balasubramanian, Priya, Yabluchanskiy, Andriy, Ashpole, Nicole M., Logan, Sreemathi, Kiss, Tamas, Ungvari, Anna, Nyúl-Tóth, Ádám, Schwartzman, Michal L., Benyo, Zoltan, Sonntag, William E., Csiszar, Anna, Ungvari, Zoltan
Published in GeroScience (01.04.2021)
Published in GeroScience (01.04.2021)
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Impaired Neurovascular Coupling and Increased Functional Connectivity in the Frontal Cortex Predict Age‐Related Cognitive Dysfunction
Mukli, Peter, Pinto, Camila B., Owens, Cameron D., Csipo, Tamas, Lipecz, Agnes, Szarvas, Zsofia, Peterfi, Anna, Langley, Ana Clara da Costa Pinaffi, Hoffmeister, Jordan, Racz, Frigyes Samuel, Perry, Jonathan W., Tarantini, Stefano, Nyúl‐Tóth, Ádám, Sorond, Farzaneh A., Yang, Yuan, James, Judith A., Kirkpatrick, Angelia C., Prodan, Calin I., Toth, Peter, Galindo, Juliette, Gardner, Andrew W., Sonntag, William E., Csiszar, Anna, Ungvari, Zoltan, Yabluchanskiy, Andriy
Published in Advanced science (01.03.2024)
Published in Advanced science (01.03.2024)
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Journal Article
Rejuvenation of cerebromicrovascular function in aged mice through heterochronic parabiosis: insights into neurovascular coupling and the impact of young blood factors
Gulej, Rafal, Nyúl-Tóth, Ádám, Csik, Boglarka, Petersen, Benjamin, Faakye, Janet, Negri, Sharon, Chandragiri, Siva Sai, Mukli, Peter, Yabluchanskiy, Andriy, Conley, Shannon, Huffman, Derek M., Csiszar, Anna, Tarantini, Stefano, Ungvari, Zoltan
Published in GeroScience (01.02.2024)
Published in GeroScience (01.02.2024)
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Journal Article
Old blood from heterochronic parabionts accelerates vascular aging in young mice: transcriptomic signature of pathologic smooth muscle remodeling
Kiss, Tamas, Nyúl-Tóth, Ádám, Gulej, Rafal, Tarantini, Stefano, Csipo, Tamas, Mukli, Peter, Ungvari, Anna, Balasubramanian, Priya, Yabluchanskiy, Andriy, Benyo, Zoltan, Conley, Shannon M., Wren, Jonathan D., Garman, Lori, Huffman, Derek M., Csiszar, Anna, Ungvari, Zoltan
Published in GeroScience (01.04.2022)
Published in GeroScience (01.04.2022)
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Journal Article
Elimination of senescent cells by treatment with Navitoclax/ABT263 reverses whole brain irradiation-induced blood-brain barrier disruption in the mouse brain
Gulej, Rafal, Nyúl-Tóth, Ádám, Ahire, Chetan, DelFavero, Jordan, Balasubramanian, Priya, Kiss, Tamas, Tarantini, Stefano, Benyo, Zoltan, Pacher, Pal, Csik, Boglarka, Yabluchanskiy, Andriy, Mukli, Peter, Kuan-Celarier, Anna, Krizbai, István A, Campisi, Judith, Sonntag, William E., Csiszar, Anna, Ungvari, Zoltan
Published in GeroScience (01.10.2023)
Published in GeroScience (01.10.2023)
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Journal Article
Preventing spontaneous cerebral microhemorrhages in aging mice: a novel approach targeting cellular senescence with ABT263/navitoclax
Faakye, Janet, Nyúl-Tóth, Ádám, Muranyi, Mihaly, Gulej, Rafal, Csik, Boglarka, Shanmugarama, Santny, Tarantini, Stefano, Negri, Sharon, Prodan, Calin, Mukli, Peter, Yabluchanskiy, Andriy, Conley, Shannon, Toth, Peter, Csiszar, Anna, Ungvari, Zoltan
Published in GeroScience (01.02.2024)
Published in GeroScience (01.02.2024)
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