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The microglial P2Y6 receptor mediates neuronal loss and memory deficits in neurodegeneration
Puigdellívol, Mar, Milde, Stefan, Vilalta, Anna, Cockram, Tom O.J., Allendorf, David H., Lee, Jeffrey Y., Dundee, Jacob M., Pampuščenko, Katryna, Borutaite, Vilmante, Nuthall, Hugh N., Brelstaff, Jack H., Spillantini, Maria Grazia, Brown, Guy C.
Published in Cell reports (Cambridge) (28.12.2021)
Published in Cell reports (Cambridge) (28.12.2021)
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Protease-activated receptor 2 activation induces behavioural changes associated with depression-like behaviour through microglial-independent modulation of inflammatory cytokines
Moudio, Serge, Willis, Ashleigh, Pytka, Karolina, Abulkassim, Roua, Brett, Ros R., Webster, Jack F., Wozny, Christian, Barbour, Mark, Jiang, Hui-Rong, Watson, David G., van Kralingen, Josie C., MacKenzie, Scott M., Daniels, Michael, McColl, Barry W., Sossick, Sandra, Nuthall, Hugh N., Bushell, Trevor J.
Published in Psychopharmacology (01.01.2022)
Published in Psychopharmacology (01.01.2022)
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PET quantification of brain O-GlcNAcase with [18F]LSN3316612 in healthy human volunteers
Lee, Jae-Hoon, Liow, Jeih-San, Paul, Soumen, Morse, Cheryl L., Haskali, Mohammad B., Manly, Lester, Shcherbinin, Sergey, Ruble, J. Craig, Kant, Nancy, Collins, Emily C., Nuthall, Hugh N., Zanotti-Fregonara, Paolo, Zoghbi, Sami S., Pike, Victor W., Innis, Robert B.
Published in EJNMMI research (14.03.2020)
Published in EJNMMI research (14.03.2020)
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Discovery and clinical translation of ceperognastat, an O‐GlcNAcase (OGA) inhibitor, for the treatment of Alzheimer's disease
Kielbasa, William, Goldsmith, Paul, Donnelly, Kevin B., Nuthall, Hugh N., Shcherbinin, Sergey, Fleisher, Adam S., Hendle, Jörg, DuBois, Susan L., Lowe, Stephen L., Zhang, Feiyu Fred, Woerly, Eric M., Dreyfus, Nicolas J.‐F., Evans, David, Gilmore, Jeremy, Mancini, Michele, Constantinescu, Cristian C., Gunn, Roger N., Russell, David S., Collins, Emily C., Brys, Miroslaw, Hutton, Michael L., Mergott, Dustin J.
Published in Alzheimer's & dementia : translational research & clinical interventions (01.10.2024)
Published in Alzheimer's & dementia : translational research & clinical interventions (01.10.2024)
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Role for Runx1 in the Proliferation and Neuronal Differentiation of Selected Progenitor Cells in the Mammalian Nervous System
Theriault, Francesca M, Nuthall, Hugh N, Dong, Zhifeng, Lo, Rita, Barnabe-Heider, Fanie, Miller, Freda D, Stifani, Stefano
Published in The Journal of neuroscience (23.02.2005)
Published in The Journal of neuroscience (23.02.2005)
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Neuroprotection induced by protease-activated receptor 2 activation is independent of Gq signalling
Moudio, Serge, Nuthall, Hugh N., Bushell, Trevor J.
Published in Brain and neuroscience advances (01.01.2025)
Published in Brain and neuroscience advances (01.01.2025)
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Evaluation of a PET Radioligand to Image O -GlcNAcase in Brain and Periphery of Rhesus Monkey and Knock-Out Mouse
Paul, Soumen, Haskali, Mohammad B., Liow, Jeih-San, Zoghbi, Sami S., Barth, Vanessa N., Kolodrubetz, Marcy Comly, Bond, Michelle R., Morse, Cheryl L., Gladding, Robert L., Frankland, Michael P., Kant, Nancy, Slieker, Lawrence, Shcherbinin, Sergey, Nuthall, Hugh N., Zanotti-Fregonara, Paolo, Hanover, John A., Jesudason, Cynthia, Pike, Victor W., Innis, Robert B.
Published in Journal of Nuclear Medicine (01.01.2019)
Published in Journal of Nuclear Medicine (01.01.2019)
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Role for Hes1-Induced Phosphorylation in Groucho-Mediated Transcriptional Repression
Nuthall, Hugh N., Husain, Junaid, McLarren, Keith W., Stifani, Stefano
Published in Molecular and Cellular Biology (01.01.2002)
Published in Molecular and Cellular Biology (01.01.2002)
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PET ligands [ 18 F]LSN3316612 and [ 11 C]LSN3316612 quantify O -linked-β- N -acetyl-glucosamine hydrolase in the brain
Lu, Shuiyu, Haskali, Mohammad B, Ruley, Kevin M, Dreyfus, Nicolas J-F, DuBois, Susan L, Paul, Soumen, Liow, Jeih-San, Morse, Cheryl L, Kowalski, Aneta, Gladding, Robert L, Gilmore, Jeremy, Mogg, Adrian J, Morin, S Michelle, Lindsay-Scott, Peter J, Ruble, J Craig, Kant, Nancy A, Shcherbinin, Sergey, Barth, Vanessa N, Johnson, Michael P, Cuadrado, Maria, Jambrina, Enrique, Mannes, Andrew J, Nuthall, Hugh N, Zoghbi, Sami S, Jesudason, Cynthia D, Innis, Robert B, Pike, Victor W
Published in Science translational medicine (13.05.2020)
Published in Science translational medicine (13.05.2020)
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A Regulatory Element in Intron 1 of the Cystic Fibrosis Transmembrane Conductance Regulator Gene
Smith, Annabel N., Barth, Maria Luiza, McDowell, Tarra L., Moulin, Danielle S., Nuthall, Hugh N., Hollingsworth, Michael A., Harris, Ann
Published in The Journal of biological chemistry (26.04.1996)
Published in The Journal of biological chemistry (26.04.1996)
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The microglial P2Y 6 receptor mediates neuronal loss and memory deficits in neurodegeneration
Puigdellívol, Mar, Milde, Stefan, Vilalta, Anna, Cockram, Tom O J, Allendorf, David H, Lee, Jeffrey Y, Dundee, Jacob M, Pampuščenko, Katryna, Borutaite, Vilmante, Nuthall, Hugh N, Brelstaff, Jack H, Spillantini, Maria Grazia, Brown, Guy C
Published in Cell reports (Cambridge) (28.12.2021)
Published in Cell reports (Cambridge) (28.12.2021)
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PET quantification of brain O-GlcNAcase with 18FLSN3316612 in healthy human volunteers
Lee, Jae-Hoon, Liow, Jeih-San, Paul, Soumen, Morse, Cheryl L, Haskali, Mohammad B, Manly, Lester, Shcherbinin, Sergey, Ruble, J Craig, Kant, Nancy, Collins, Emily C, Nuthall, Hugh N, Zanotti-Fregonara, Paolo, Zoghbi, Sami S, Pike, Victor W, Innis, Robert B
Published in EJNMMI research (14.03.2020)
Published in EJNMMI research (14.03.2020)
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O-GLCNACASE (OGA) INHIBITOR COMBINATION THERAPY
NUTHALL, Hugh N, FLEISHER, Adam S, BIGLAN, Kevin, MERGOTT, Dustin James
Year of Publication 28.08.2024
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Year of Publication 28.08.2024
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