Loading…
An Erythroid Enhancer of BCL11A Subject to Genetic Variation Determines Fetal Hemoglobin Level
Bauer, Daniel E., Kamran, Sophia C., Lessard, Samuel, Xu, Jian, Fujiwara, Yuko, Lin, Carrie, Shao, Zhen, Canver, Matthew C., Smith, Elenoe C., Pinello, Luca, Sabo, Peter J., Vierstra, Jeff, Voit, Richard A., Yuan, Guo-Cheng, Porteus, Matthew H., Stamatoyannopoulos, John A., Lettre, Guillaume, Orkin, Stuart H.
Published in Science (American Association for the Advancement of Science) (11.10.2013)
Published in Science (American Association for the Advancement of Science) (11.10.2013)
Get full text
Journal Article
Loading…
Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus
Readhead, Ben, Haure-Mirande, Jean-Vianney, Funk, Cory C., Richards, Matthew A., Shannon, Paul, Haroutunian, Vahram, Sano, Mary, Liang, Winnie S., Beckmann, Noam D., Price, Nathan D., Reiman, Eric M., Schadt, Eric E., Ehrlich, Michelle E., Gandy, Sam, Dudley, Joel T.
Published in Neuron (Cambridge, Mass.) (11.07.2018)
Published in Neuron (Cambridge, Mass.) (11.07.2018)
Get full text
Journal Article
Loading…
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture
Stuart, Philip E., Nair, Rajan P., Tsoi, Lam C., Tejasvi, Trilokraj, Das, Sayantan, Kang, Hyun Min, Ellinghaus, Eva, Chandran, Vinod, Callis-Duffin, Kristina, Ike, Robert, Li, Yanming, Wen, Xiaoquan, Enerbäck, Charlotta, Gudjonsson, Johann E., Kõks, Sulev, Kingo, Külli, Esko, Tõnu, Mrowietz, Ulrich, Reis, Andre, Wichmann, H. Erich, Gieger, Christian, Hoffmann, Per, Nöthen, Markus M., Winkelmann, Juliane, Kunz, Manfred, Moreta, Elvia G., Mease, Philip J., Ritchlin, Christopher T., Bowcock, Anne M., Krueger, Gerald G., Lim, Henry W., Weidinger, Stephan, Weichenthal, Michael, Voorhees, John J., Rahman, Proton, Gregersen, Peter K., Franke, Andre, Gladman, Dafna D., Abecasis, Gonçalo R., Elder, James T.
Published in American journal of human genetics (03.12.2015)
Published in American journal of human genetics (03.12.2015)
Get full text
Journal Article
Loading…
BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis
Canver, Matthew C., Smith, Elenoe C., Sher, Falak, Pinello, Luca, Sanjana, Neville E., Shalem, Ophir, Chen, Diane D., Schupp, Patrick G., Vinjamur, Divya S., Garcia, Sara P., Luc, Sidinh, Kurita, Ryo, Nakamura, Yukio, Fujiwara, Yuko, Maeda, Takahiro, Yuan, Guo-Cheng, Zhang, Feng, Orkin, Stuart H., Bauer, Daniel E.
Published in Nature (London) (12.11.2015)
Published in Nature (London) (12.11.2015)
Get full text
Journal Article
Loading…
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci
De Jager, Philip L, Srivastava, Gyan, Lunnon, Katie, Burgess, Jeremy, Schalkwyk, Leonard C, Yu, Lei, Eaton, Matthew L, Keenan, Brendan T, Ernst, Jason, McCabe, Cristin, Tang, Anna, Raj, Towfique, Replogle, Joseph, Brodeur, Wendy, Gabriel, Stacey, Chai, High S, Younkin, Curtis, Younkin, Steven G, Zou, Fanggeng, Szyf, Moshe, Epstein, Charles B, Schneider, Julie A, Bernstein, Bradley E, Meissner, Alex, Ertekin-Taner, Nilufer, Chibnik, Lori B, Kellis, Manolis, Mill, Jonathan, Bennett, David A
Published in Nature neuroscience (01.09.2014)
Published in Nature neuroscience (01.09.2014)
Get full text
Journal Article
Loading…
The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
Gu, Xin, Nardone, Christopher, Kamitaki, Nolan, Mao, Aoyue, Elledge, Stephen J., Greenberg, Michael E.
Published in Science (American Association for the Advancement of Science) (25.08.2023)
Published in Science (American Association for the Advancement of Science) (25.08.2023)
Get full text
Journal Article
Loading…
Reduction of Macrophage Infiltration and Chemoattractant Gene Expression Changes in White Adipose Tissue of Morbidly Obese Subjects After Surgery-Induced Weight Loss
Cancello, Raffaella, Henegar, Corneliu, Viguerie, Nathalie, Taleb, Soraya, Poitou, Christine, Rouault, Christine, Coupaye, Muriel, Pelloux, Veronique, Hugol, Danielle, Bouillot, Jean-Luc, Bouloumié, Anne, Barbatelli, Giorgio, Cinti, Saverio, Svensson, Per-Arne, Barsh, Gregory S., Zucker, Jean-Daniel, Basdevant, Arnaud, Langin, Dominique, Clément, Karine
Published in Diabetes (New York, N.Y.) (01.08.2005)
Published in Diabetes (New York, N.Y.) (01.08.2005)
Get full text
Journal Article
Loading…
Point-of-care whole-exome sequencing of idiopathic male infertility
Fakhro, Khalid A, Elbardisi, Haitham, Arafa, Mohamed, Robay, Amal, Rodriguez-Flores, Juan L, Al-Shakaki, Alya, Syed, Najeeb, Mezey, Jason G, Abi Khalil, Charbel, Malek, Joel A, Al-Ansari, Abdulla, Al Said, Sami, Crystal, Ronald G
Published in Genetics in medicine (01.11.2018)
Published in Genetics in medicine (01.11.2018)
Get full text
Journal Article
Loading…
Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes
Graubert, Timothy A, Shen, Dong, Ding, Li, Okeyo-Owuor, Theresa, Lunn, Cara L, Shao, Jin, Krysiak, Kilannin, Harris, Christopher C, Koboldt, Daniel C, Larson, David E, McLellan, Michael D, Dooling, David J, Abbott, Rachel M, Fulton, Robert S, Schmidt, Heather, Kalicki-Veizer, Joelle, O'Laughlin, Michelle, Grillot, Marcus, Baty, Jack, Heath, Sharon, Frater, John L, Nasim, Talat, Link, Daniel C, Tomasson, Michael H, Westervelt, Peter, DiPersio, John F, Mardis, Elaine R, Ley, Timothy J, Wilson, Richard K, Walter, Matthew J
Published in Nature genetics (11.12.2011)
Published in Nature genetics (11.12.2011)
Get full text
Journal Article
Loading…
Prognostic role and implications of mutation status of tumor suppressor gene ARID1A in cancer: a systematic review and meta-analysis
Luchini, Claudio, Veronese, Nicola, Solmi, Marco, Cho, Hanbyoul, Kim, Jae-Hoon, Chou, Angela, Gill, Anthony J., Faraj, Sheila F., Chaux, Alcides, Netto, George J., Nakayama, Kentaro, Kyo, Satoru, Lee, Soo Young, Kim, Duck-Woo, Yousef, George M., Scorilas, Andreas, Nelson, Gregg S., Köbel, Martin, Kalloger, Steve E., Schaeffer, David F., Yan, Hai-Bo, Liu, Feng, Yokoyama, Yoshihito, Zhang, Xianyu, Pang, Da, Lichner, Zsuzsanna, Sergi, Giuseppe, Manzato, Enzo, Capelli, Paola, Wood, Laura D., Scarpa, Aldo, Correll, Christoph U.
Published in Oncotarget (17.11.2015)
Published in Oncotarget (17.11.2015)
Get full text
Journal Article
Loading…
A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorder
Ikeda, M, Takahashi, A, Kamatani, Y, Okahisa, Y, Kunugi, H, Mori, N, Sasaki, T, Ohmori, T, Okamoto, Y, Kawasaki, H, Shimodera, S, Kato, T, Yoneda, H, Yoshimura, R, Iyo, M, Matsuda, K, Akiyama, M, Ashikawa, K, Kashiwase, K, Tokunaga, K, Kondo, K, Saito, T, Shimasaki, A, Kawase, K, Kitajima, T, Matsuo, K, Itokawa, M, Someya, T, Inada, T, Hashimoto, R, Inoue, T, Akiyama, K, Tanii, H, Arai, H, Kanba, S, Ozaki, N, Kusumi, I, Yoshikawa, T, Kubo, M, Iwata, N
Published in Molecular psychiatry (01.03.2018)
Published in Molecular psychiatry (01.03.2018)
Get full text
Journal Article
Loading…
TOR1AIP1-Associated Nuclear Envelopathies
Mackels, Laurane, Liu, Xincheng, Bonne, Gisèle, Servais, Laurent
Published in International journal of molecular sciences (07.04.2023)
Published in International journal of molecular sciences (07.04.2023)
Get full text
Journal Article
Web Resource
Loading…
Loading…
SMARCA4/BRG1-Deficient Non-Small Cell Lung Carcinomas: A Case Series and Review of the Literature
Nambirajan, Aruna, Singh, Varsha, Bhardwaj, Nishu, Mittal, Saurabh, Kumar, Sunil, Jain, Deepali
Published in Archives of pathology & laboratory medicine (1976) (01.01.2021)
Published in Archives of pathology & laboratory medicine (1976) (01.01.2021)
Get full text
Journal Article
Loading…
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4
Sklar, Pamela, Ripke, Stephan, Scott, Laura J, Andreassen, Ole A, Cichon, Sven, Craddock, Nick, Edenberg, Howard J, Nurnberger, John I, Rietschel, Marcella, Blackwood, Douglas, Corvin, Aiden, Flickinger, Matthew, Guan, Weihua, Mattingsdal, Morten, McQuillin, Andrew, Kwan, Phoenix, Wienker, Thomas F, Daly, Mark, Dudbridge, Frank, Holmans, Peter A, Lin, Danyu, Burmeister, Margit, Greenwood, Tiffany A, Hamshere, Marian L, Muglia, Pierandrea, Smith, Erin N, Zandi, Peter P, Nievergelt, Caroline M, McKinney, Rebecca, Shilling, Paul D, Schork, Nicholas J, Bloss, Cinnamon S, Foroud, Tatiana, Koller, Daniel L, Gershon, Elliot S, Liu, Chunyu, Badner, Judith A, Scheftner, William A, Lawson, William B, Nwulia, Evaristus A, Hipolito, Maria, Coryell, William, Rice, John, Byerley, William, McMahon, Francis J, Schulze, Thomas G, Berrettini, Wade, Lohoff, Falk W, Potash, James B, Mahon, Pamela B, McInnis, Melvin G, Zöllner, Sebastian, Zhang, Peng, Craig, David W, Szelinger, Szabocls, Barrett, Thomas B, Breuer, René, Meier, Sandra, Strohmaier, Jana, Witt, Stephanie H, Tozzi, Federica, Farmer, Anne, McGuffin, Peter, Strauss, John, Xu, Wei, Kennedy, James L, Vincent, John B, Matthews, Keith, Day, Richard, Ferreira, Manuel A, O'Dushlaine, Colm, Perlis, Roy, Raychaudhuri, Soumya, Ruderfer, Douglas, Lee, Phil H, Smoller, Jordan W, Li, Jun, Absher, Devin, Bunney, William E, Barchas, Jack D, Schatzberg, Alan F, Jones, Edward G, Meng, Fan, Thompson, Robert C, Watson, Stanley J, Myers, Richard M, Akil, Huda, Boehnke, Michael, Chambert, Kim, Moran, Jennifer, Scolnick, Ed, Djurovic, Srdjan, Melle, Ingrid, Morken, Gunnar, Gill, Michael, Morris, Derek, Quinn, Emma, Mühleisen, Thomas W, Degenhardt, Franziska A, Mattheisen, Manuel
Published in Nature genetics (01.10.2011)
Published in Nature genetics (01.10.2011)
Get full text
Journal Article
Loading…
Association Between Variants of PRDM1 and NDP52 and Crohn's Disease, Based on Exome Sequencing and Functional Studies
Ellinghaus, David, Zhang, Hu, Zeissig, Sebastian, Lipinski, Simone, Till, Andreas, Jiang, Tao, Stade, Björn, Bromberg, Yana, Ellinghaus, Eva, Keller, Andreas, Rivas, Manuel A., Skieceviciene, Jurgita, Doncheva, Nadezhda T., Liu, Xiao, Liu, Qing, Jiang, Fuman, Forster, Michael, Mayr, Gabriele, Albrecht, Mario, Häsler, Robert, Boehm, Bernhard O., Goodall, Jane, Berzuini, Carlo R., Lee, James, Andersen, Vibeke, Vogel, Ulla, Kupcinskas, Limas, Kayser, Manfred, Krawczak, Michael, Nikolaus, Susanna, Weersma, Rinse K., Ponsioen, Cyriel Y., Sans, Miquel, Wijmenga, Cisca, Strachan, David P., McArdle, Wendy L., Vermeire, Séverine, Rutgeerts, Paul, Sanderson, Jeremy D., Mathew, Christopher G., Vatn, Morten H., Wang, Jun, Nöthen, Markus M., Duerr, Richard H., Büning, Carsten, Brand, Stephan, Glas, Jürgen, Winkelmann, Juliane, Illig, Thomas, Latiano, Anna, Annese, Vito, Halfvarson, Jonas, D'Amato, Mauro, Daly, Mark J., Nothnagel, Michael, Karlsen, Tom H., Subramani, Suresh, Rosenstiel, Philip, Schreiber, Stefan, Parkes, Miles, Franke, Andre
Published in Gastroenterology (New York, N.Y. 1943) (01.08.2013)
Published in Gastroenterology (New York, N.Y. 1943) (01.08.2013)
Get full text
Journal Article
Loading…
Genomic characterization of sarcomatoid transformation in clear cell renal cell carcinoma
Bi, Mark, Zhao, Siming, Said, Jonathan W., Merino, Maria J., Adeniran, Adebowale J., Xie, Zuoquan, Nawaf, Cayce B., Choi, Jaehyuk, Belldegrun, Arie S., Pantuck, Allan J., Kluger, Harriet M., Bilgüvar, Kaya, Lifton, Richard P., Shuch, Brian
Published in Proceedings of the National Academy of Sciences - PNAS (23.02.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (23.02.2016)
Get full text
Journal Article
Loading…
Nuclear protein FNBP4: A novel inhibitor of non-diaphanous formin FMN1-mediated actin cytoskeleton dynamics
Das, Shubham, Das, Saikat, Maity, Amrita, Maiti, Sankar
Published in The Journal of biological chemistry (01.06.2025)
Published in The Journal of biological chemistry (01.06.2025)
Get full text
Journal Article
Loading…
Loading…
Biological and clinical changes in premanifest and early stage Huntington's disease in the TRACK-HD study: the 12-month longitudinal analysis
Tabrizi, Sarah J, Scahill, Rachael I, Durr, Alexandra, Roos, Raymund AC, Leavitt, Blair R, Jones, Rebecca, Landwehrmeyer, G Bernhard, Fox, Nick C, Johnson, Hans, Hicks, Stephen L, Kennard, Christopher, Craufurd, David, Frost, Chris, Langbehn, Douglas R, Reilmann, Ralf, Stout, Julie C
Published in Lancet neurology (01.01.2011)
Published in Lancet neurology (01.01.2011)
Get full text
Journal Article