A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity
Compte, Marta, Harwood, Seandean Lykke, Muñoz, Ines G., Navarro, Rocio, Zonca, Manuela, Perez-Chacon, Gema, Erce-Llamazares, Ainhoa, Merino, Nekane, Tapia-Galisteo, Antonio, Cuesta, Angel M., Mikkelsen, Kasper, Caleiras, Eduardo, Nuñez-Prado, Natalia, Aznar, M. Angela, Lykkemark, Simon, Martínez-Torrecuadrada, Jorge, Melero, Ignacio, Blanco, Francisco J., Bernardino de la Serna, Jorge, Zapata, Juan M., Sanz, Laura, Alvarez-Vallina, Luis
Published in Nature communications (15.11.2018)
Published in Nature communications (15.11.2018)
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Journal Article
The coming of age of engineered multivalent antibodies
Nuñez-Prado, Natalia, Compte, Marta, Harwood, Seandean, Álvarez-Méndez, Ana, Lykkemark, Simon, Sanz, Laura, Álvarez-Vallina, Luis
Published in Drug discovery today (01.05.2015)
Published in Drug discovery today (01.05.2015)
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Journal Article
Role of nucleotide‐binding oligomerization domain 1 (NOD1) in pericyte‐mediated vascular inflammation
Navarro, Rocío, Delgado‐Wicke, Pablo, Nuñez‐Prado, Natalia, Compte, Marta, Blanco‐Toribio, Ana, Nuñez, Gabriel, Álvarez‐Vallina, Luis, Sanz, Laura
Published in Journal of cellular and molecular medicine (01.05.2016)
Published in Journal of cellular and molecular medicine (01.05.2016)
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Journal Article
CARbodies: Human Antibodies Against Cell Surface Tumor Antigens Selected From Repertoires Displayed on T Cell Chimeric Antigen Receptors
Alonso-Camino, Vanesa, Sánchez-Martín, David, Compte, Marta, Nuñez-Prado, Natalia, Diaz, Rosa M, Vile, Richard, Alvarez-Vallina, Luis
Published in Molecular therapy. Nucleic acids (01.05.2013)
Published in Molecular therapy. Nucleic acids (01.05.2013)
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Journal Article
In Vivo Secretion of Bispecific Antibodies Recruiting Lymphocytic Effector Cells
Compte, Marta, Nuñez-Prado, Natalia, Sanz, Laura, Alvarez-Vallina, Luis
Published in Antibodies (Basel) (01.09.2013)
Published in Antibodies (Basel) (01.09.2013)
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Journal Article
Book Review
ATTACK, a novel bispecific T cell-recruiting antibody with trivalent EGFR binding and monovalent CD3 binding for cancer immunotherapy
Harwood, Seandean Lykke, Alvarez-Cienfuegos, Ana, Nuñez-Prado, Natalia, Compte, Marta, Hernández-Pérez, Sara, Merino, Nekane, Bonet, Jaume, Navarro, Rocio, Van Bergen en Henegouwen, Paul M. P., Lykkemark, Simon, Mikkelsen, Kasper, Mølgaard, Kasper, Jabs, Frederic, Sanz, Laura, Blanco, Francisco J., Roda-Navarro, Pedro, Alvarez-Vallina, Luis
Published in Oncoimmunology (02.01.2018)
Published in Oncoimmunology (02.01.2018)
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Journal Article
Bispecific light T-cell engagers for gene-based immunotherapy of epidermal growth factor receptor (EGFR)-positive malignancies
Mølgaard, Kasper, Harwood, Seandean L., Compte, Marta, Merino, Nekane, Bonet, Jaume, Alvarez-Cienfuegos, Ana, Mikkelsen, Kasper, Nuñez-Prado, Natalia, Alvarez-Mendez, Ana, Sanz, Laura, Blanco, Francisco J., Alvarez-Vallina, Luis
Published in Cancer Immunology, Immunotherapy (01.08.2018)
Published in Cancer Immunology, Immunotherapy (01.08.2018)
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Journal Article
Intramolecular trimerization, a novel strategy for making multispecific antibodies with controlled orientation of the antigen binding domains
Alvarez-Cienfuegos, Ana, Nuñez-Prado, Natalia, Compte, Marta, Cuesta, Angel M., Blanco-Toribio, Ana, Harwood, Seandean Lykke, Villate, Maider, Merino, Nekane, Bonet, Jaume, Navarro, Rocio, Muñoz-Briones, Clara, Sørensen, Karen Marie Juul, Mølgaard, Kasper, Oliva, Baldo, Sanz, Laura, Blanco, Francisco J., Alvarez-Vallina, Luis
Published in Scientific reports (27.06.2016)
Published in Scientific reports (27.06.2016)
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Journal Article
Functional comparison of single-chain and two-chain anti-CD3-based bispecific antibodies in gene immunotherapy applications
Compte, Marta, Álvarez-Cienfuegos, Ana, Nuñez-Prado, Natalia, Sainz-Pastor, Noelia, Blanco-Toribio, Ana, Pescador, Nuria, Sanz, Laura, Álvarez-Vallina, Luis
Published in Oncoimmunology (01.05.2014)
Published in Oncoimmunology (01.05.2014)
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Journal Article
Efficient production of single-chain fragment variable-based N-terminal trimerbodies in Pichia pastoris
Blanco-Toribio, Ana, Lacadena, Javier, Nuñez-Prado, Natalia, Álvarez-Cienfuegos, Ana, Villate, Maider, Compte, Marta, Sanz, Laura, Blanco, Francisco J, Álvarez-Vallina, Luis
Published in Microbial cell factories (12.08.2014)
Published in Microbial cell factories (12.08.2014)
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Journal Article
Immunotherapeutic organoids: A new approach to cancer treatment
Compte, Marta, Nuñez-Prado, Natalia, Sanz, Laura, Álvarez-Vallina, Luís
Published in Biomatter (Austin, TX) (01.01.2013)
Published in Biomatter (Austin, TX) (01.01.2013)
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Journal Article