Preserving and enhancing mitochondrial function after stroke to protect and repair the neurovascular unit: novel opportunities for nanoparticle-based drug delivery
Novorolsky, Robyn J, Kasheke, Gracious D S, Hakim, Antoine, Foldvari, Marianna, Dorighello, Gabriel G, Sekler, Israel, Vuligonda, Vidyasagar, Sanders, Martin E, Renden, Robert B, Wilson, Justin J, Robertson, George S
Published in Frontiers in cellular neuroscience (07.07.2023)
Published in Frontiers in cellular neuroscience (07.07.2023)
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Journal Article
The cell-permeable mitochondrial calcium uniporter inhibitor Ru265 preserves cortical neuron respiration after lethal oxygen glucose deprivation and reduces hypoxic/ischemic brain injury
Novorolsky, Robyn J, Nichols, Matthew, Kim, Jong S, Pavlov, Evgeny V, J Woods, Joshua, Wilson, Justin J, Robertson, George S
Published in Journal of cerebral blood flow and metabolism (01.06.2020)
Published in Journal of cerebral blood flow and metabolism (01.06.2020)
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Journal Article
The mitochondrial calcium uniporter inhibitor Ru265 increases neuronal excitability and reduces neurotransmission via off‐target effects
Xu, Peng, Swain, Sarpras, Novorolsky, Robyn J., Garcia, Esperanza, Huang, Zhouyang, Snutch, Terrance P., Wilson, Justin J., Robertson, George S., Renden, Robert B.
Published in British journal of pharmacology (01.09.2024)
Published in British journal of pharmacology (01.09.2024)
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Journal Article
Neuronal mitochondrial calcium uniporter deficiency exacerbates axonal injury and suppresses remyelination in mice subjected to experimental autoimmune encephalomyelitis
Holman, Scott P., Lobo, Aurelio S., Novorolsky, Robyn J., Nichols, Matthew, Fiander, Maximillian D.J., Konda, Prathyusha, Kennedy, Barry E., Gujar, Shashi, Robertson, George S.
Published in Experimental neurology (01.11.2020)
Published in Experimental neurology (01.11.2020)
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Journal Article
Supramolecular delivery of dinuclear ruthenium and osmium MCU inhibitors
Bigham, Nicholas P, Novorolsky, Robyn J, Davis, Keana R, Zou, Haipei, MacMillan, Samantha N, Stevenson, Michael J, Robertson, George S, Wilson, Justin J
Published in Inorganic chemistry frontiers (06.08.2024)
Published in Inorganic chemistry frontiers (06.08.2024)
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Dinuclear nitrido-bridged osmium complexes inhibit the mitochondrial calcium uniporter and protect cortical neurons against lethal oxygen-glucose deprivation
Woods, Joshua J, Novorolsky, Robyn J, Bigham, Nicholas P, Robertson, George S, Wilson, Justin J
Published in RSC chemical biology (04.01.2023)
Published in RSC chemical biology (04.01.2023)
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Journal Article
Dinuclear nitrido-bridged osmium complexes inhibit the mitochondrial calcium uniporter and protect cortical neurons against lethal oxygenglucose deprivation
Woods, Joshua J, Novorolsky, Robyn J, Bigham, Nicholas P, Robertson, George S, Wilson, Justin J
Published in RSC chemical biology (04.01.2023)
Published in RSC chemical biology (04.01.2023)
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Journal Article