ATP-Citrate Lyase as a Target for Hypolipidemic Intervention. 2. Synthesis and Evaluation of (3R,5S)-ω-Substituted-3-carboxy-3,5-dihydroxyalkanoic Acids and Their γ-Lactone Prodrugs as Inhibitors of the Enzyme in Vitro and in Vivo
Gribble, Andrew D, Ife, Robert J, Shaw, Antony, McNair, David, Novelli, Christine E, Bakewell, Susan, Shah, Virendra P, Dolle, Roland E, Groot, Pieter H, Pearce, Nigel, Yates, John, Tew, David, Boyd, Helen, Ashman, Stephen, Eggleston, Drake S, Haltiwanger, R. Curtis, Okafo, George
Published in Journal of medicinal chemistry (10.09.1998)
Published in Journal of medicinal chemistry (10.09.1998)
Get full text
Journal Article
ATP-Citrate Lyase as a Target for Hypolipidemic Intervention. Design and Synthesis of 2-Substituted Butanedioic Acids as Novel, Potent Inhibitors of the Enzyme
Gribble, Andrew D, Dolle, Roland E, Shaw, Antony, McNair, David, Novelli, Riccardo, Novelli, Christine E, Slingsby, Brian P, Shah, Virendra P, Tew, David, Saxty, Barbara A, Allen, Mark, Groot, Pieter H, Pearce, Nigel, Yates, John
Published in Journal of medicinal chemistry (30.08.1996)
Published in Journal of medicinal chemistry (30.08.1996)
Get full text
Journal Article