Ten Years of Tau-Targeted Immunotherapy: The Path Walked and the Roads Ahead
Novak, Petr, Kontsekova, Eva, Zilka, Norbert, Novak, Michal
Published in Frontiers in neuroscience (02.11.2018)
Published in Frontiers in neuroscience (02.11.2018)
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Journal Article
First-in-man tau vaccine targeting structural determinants essential for pathological tau-tau interaction reduces tau oligomerisation and neurofibrillary degeneration in an Alzheimer's disease model
Kontsekova, Eva, Zilka, Norbert, Kovacech, Branislav, Novak, Petr, Novak, Michal
Published in Alzheimer's research & therapy (01.08.2014)
Published in Alzheimer's research & therapy (01.08.2014)
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Journal Article
Tau Conformation as a Target for Disease-Modifying Therapy: The Role of Truncation
Novak, Petr, Cehlar, Ondrej, Skrabana, Rostislav, Novak, Michal
Published in Journal of Alzheimer's disease (01.01.2018)
Published in Journal of Alzheimer's disease (01.01.2018)
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Journal Article
Safety and immunogenicity of the tau vaccine AADvac1 in patients with Alzheimer's disease: a randomised, double-blind, placebo-controlled, phase 1 trial
Novak, Petr, Dr, Schmidt, Reinhold, Prof, Kontsekova, Eva, Prof, Zilka, Norbert, PhD, Kovacech, Branislav, PhD, Skrabana, Rostislav, PhD, Vince-Kazmerova, Zuzana, PhD, Katina, Stanislav, PhD, Fialova, Lubica, PhD, Prcina, Michal, PhD, Parrak, Vojtech, MD, Dal-Bianco, Peter, MD, Brunner, Martin, MD, Staffen, Wolfgang, MD, Rainer, Michael, MD, Ondrus, Matej, MD, Ropele, Stefan, Ing, Smisek, Miroslav, MD, Sivak, Roman, Ing, Winblad, Bengt, Prof, Novak, Michal, Prof
Published in Lancet neurology (01.02.2017)
Published in Lancet neurology (01.02.2017)
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Journal Article
Repeat-based holocentromeres influence genome architecture and karyotype evolution
Hofstatter, Paulo G., Thangavel, Gokilavani, Lux, Thomas, Neumann, Pavel, Vondrak, Tihana, Novak, Petr, Zhang, Meng, Costa, Lucas, Castellani, Marco, Scott, Alison, Toegelová, Helena, Fuchs, Joerg, Mata-Sucre, Yennifer, Dias, Yhanndra, Vanzela, André L.L., Huettel, Bruno, Almeida, Cicero C.S., Šimková, Hana, Souza, Gustavo, Pedrosa-Harand, Andrea, Macas, Jiri, Mayer, Klaus F.X., Houben, Andreas, Marques, André
Published in Cell (18.08.2022)
Published in Cell (18.08.2022)
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Journal Article
Branched chain amino acid metabolism profiles in progressive human nonalcoholic fatty liver disease
Lake, April D., Novak, Petr, Shipkova, Petia, Aranibar, Nelly, Robertson, Donald G., Reily, Michael D., Lehman-McKeeman, Lois D., Vaillancourt, Richard R., Cherrington, Nathan J.
Published in Amino acids (01.03.2015)
Published in Amino acids (01.03.2015)
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Journal Article
On the utility of cerebrospinal fluid biomarkers in canine neurological disorders
Smolek, Tomas, Vince-Kazmerova, Zuzana, Hanes, Jozef, Stevens, Eva, Palus, Viktor, Hajek, Ivo, Katina, Stanislav, Novak, Petr, Zilka, Norbert
Published in Scientific reports (15.10.2024)
Published in Scientific reports (15.10.2024)
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Journal Article
Decreased hepatotoxic bile acid composition and altered synthesis in progressive human nonalcoholic fatty liver disease
Lake, April D., Novak, Petr, Shipkova, Petia, Aranibar, Nelly, Robertson, Donald, Reily, Michael D., Lu, Zhenqiang, Lehman-McKeeman, Lois D., Cherrington, Nathan J.
Published in Toxicology and applied pharmacology (15.04.2013)
Published in Toxicology and applied pharmacology (15.04.2013)
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Journal Article
Preferred β-lactone synthesis can explain high rate of false-negative results in the detection of OXA-48-like carbapenemases
Studentova, Vendula, Sudova, Vendula, Bitar, Ibrahim, Paskova, Veronika, Moravec, Jiri, Pompach, Petr, Volny, Michael, Novak, Petr, Hrabak, Jaroslav
Published in Scientific reports (23.12.2022)
Published in Scientific reports (23.12.2022)
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Journal Article
The adaptive endoplasmic reticulum stress response to lipotoxicity in progressive human nonalcoholic fatty liver disease
Lake, April D, Novak, Petr, Hardwick, Rhiannon N, Flores-Keown, Brieanna, Zhao, Fei, Klimecki, Walter T, Cherrington, Nathan J
Published in Toxicological sciences (01.01.2014)
Published in Toxicological sciences (01.01.2014)
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Journal Article
Agglomerative epigenetic aberrations are a common event in human breast cancer
Novak, Petr, Jensen, Taylor, Oshiro, Marc M, Watts, George S, Kim, Christina J, Futscher, Bernard W
Published in Cancer research (Chicago, Ill.) (15.10.2008)
Published in Cancer research (Chicago, Ill.) (15.10.2008)
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Journal Article
Preparation of Magnetite by Thermally Induced Decomposition of Ferrous Oxalate Dihydrate in the Combined Atmosphere
Kopp, Josef, Novak, Petr, Kaslik, Josef, Pechousek, Jiri
Published in Acta chimica Slovenica (01.06.2019)
Published in Acta chimica Slovenica (01.06.2019)
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Journal Article
FUNDAMANT: an interventional 72-week phase 1 follow-up study of AADvac1, an active immunotherapy against tau protein pathology in Alzheimer's disease
Novak, Petr, Schmidt, Reinhold, Kontsekova, Eva, Kovacech, Branislav, Smolek, Tomas, Katina, Stanislav, Fialova, Lubica, Prcina, Michal, Parrak, Vojtech, Dal-Bianco, Peter, Brunner, Martin, Staffen, Wolfgang, Rainer, Michael, Ondrus, Matej, Ropele, Stefan, Smisek, Miroslav, Sivak, Roman, Zilka, Norbert, Winblad, Bengt, Novak, Michal
Published in Alzheimer's research & therapy (24.10.2018)
Published in Alzheimer's research & therapy (24.10.2018)
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Journal Article
Analysis of Global and Absorption, Distribution, Metabolism, and Elimination Gene Expression in the Progressive Stages of Human Nonalcoholic Fatty Liver Disease
LAKE, April D, NOVAK, Petr, FISHER, Craig D, JACKSON, Jonathan P, HARDWICK, Rhiannon N, DEAN BILLHEIMER, D, KLIMECKI, Walter T, CHERRINGTON, Nathan J
Published in Drug metabolism and disposition (01.10.2011)
Published in Drug metabolism and disposition (01.10.2011)
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Journal Article
Early-onset pulmonary and cutaneous vasculitis driven by constitutively active SRC-family kinase HCK
Kanderova, Veronika, Svobodova, Tamara, Borna, Simon, Fejtkova, Martina, Martinu, Vendula, Paderova, Jana, Svaton, Michael, Kralova, Jarmila, Fronkova, Eva, Klocperk, Adam, Pruhova, Stepanka, Lee-Kirsch, Min Ae, Hornofova, Ludmila, Koblizek, Miroslav, Novak, Petr, Zimmermannova, Olga, Parackova, Zuzana, Sediva, Anna, Kalina, Tomas, Janda, Ales, Kayserova, Jana, Dvorakova, Marcela, Macek, Milan, Pohunek, Petr, Sedlacek, Petr, Poh, Ashleigh, Ernst, Matthias, Brdicka, Tomas, Hrusak, Ondrej, Lebl, Jan
Published in Journal of allergy and clinical immunology (01.04.2022)
Published in Journal of allergy and clinical immunology (01.04.2022)
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Journal Article
PqqE from Methylobacterium extorquens AM1: a radical S-adenosyl-l-methionine enzyme with an unusual tolerance to oxygen
Saichana, Natsaran, Tanizawa, Katsuyuki, Pechoušek, Jiří, Novák, Petr, Yakushi, Toshiharu, Toyama, Hirohide, Frébortová, Jitka
Published in Journal of biochemistry (Tokyo) (01.01.2016)
Published in Journal of biochemistry (Tokyo) (01.01.2016)
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Journal Article
ADAMANT: a placebo-controlled randomized phase 2 study of AADvac1, an active immunotherapy against pathological tau in Alzheimer's disease
Novak, Petr, Kovacech, Branislav, Katina, Stanislav, Schmidt, Reinhold, Scheltens, Philip, Kontsekova, Eva, Ropele, Stefan, Fialova, Lubica, Kramberger, Milica, Paulenka-Ivanovova, Natalia, Smisek, Miroslav, Hanes, Jozef, Stevens, Eva, Kovac, Andrej, Sutovsky, Stanislav, Parrak, Vojtech, Koson, Peter, Prcina, Michal, Galba, Jaroslav, Cente, Martin, Hromadka, Tomas, Filipcik, Peter, Piestansky, Juraj, Samcova, Maria, Prenn-Gologranc, Carmen, Sivak, Roman, Froelich, Lutz, Fresser, Michal, Rakusa, Martin, Harrison, John, Hort, Jakub, Otto, Markus, Tosun, Duygu, Ondrus, Matej, Winblad, Bengt, Novak, Michal, Zilka, Norbert
Published in Nature aging (01.06.2021)
Published in Nature aging (01.06.2021)
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