Discovery of Aryl Aminoquinazoline Pyridones as Potent, Selective, and Orally Efficacious Inhibitors of Receptor Tyrosine Kinase c-Kit
Hu, Essa, Tasker, Andrew, White, Ryan D, Kunz, Roxanne K, Human, Jason, Chen, Ning, Bürli, Roland, Hungate, Randall, Novak, Perry, Itano, Andrea, Zhang, Xuxia, Yu, Violeta, Nguyen, Yen, Tudor, Yanyan, Plant, Matthew, Flynn, Shaun, Xu, Yang, Meagher, Kristin L, Whittington, Douglas A, Ng, Gordon Y
Published in Journal of medicinal chemistry (12.06.2008)
Published in Journal of medicinal chemistry (12.06.2008)
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Novel 2-Aminopyrimidine Carbamates as Potent and Orally Active Inhibitors of Lck: Synthesis, SAR, and in Vivo Antiinflammatory Activity
Martin, Matthew W, Newcomb, John, Nunes, Joseph J, McGowan, David C, Armistead, David M, Boucher, Christina, Buchanan, John L, Buckner, William, Chai, Lilly, Elbaum, Daniel, Epstein, Linda F, Faust, Theodore, Flynn, Shaun, Gallant, Paul, Gore, Anu, Gu, Yan, Hsieh, Faye, Huang, Xin, Lee, Josie H, Metz, Daniela, Middleton, Scot, Mohn, Deanna, Morgenstern, Kurt, Morrison, Michael J, Novak, Perry M, Oliveira-dos-Santos, Antonio, Powers, David, Rose, Paul, Schneider, Stephen, Sell, Stephanie, Tudor, Yanyan, Turci, Susan M, Welcher, Andrew A, White, Ryan D, Zack, Debra, Zhao, Huilin, Zhu, Li, Zhu, Xiaotian, Ghiron, Chiara, Amouzegh, Patricia, Ermann, Monika, Jenkins, James, Johnston, David, Napier, Spencer, Power, Eoin
Published in Journal of medicinal chemistry (10.08.2006)
Published in Journal of medicinal chemistry (10.08.2006)
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Discovery of 2,4-bis-arylamino-1,3-pyrimidines as insulin-like growth factor-1 receptor (IGF-1R) inhibitors
Buchanan, John L., Newcomb, John R., Carney, David P., Chaffee, Stuart C., Chai, Lilly, Cupples, Rod, Epstein, Linda F., Gallant, Paul, Gu, Yan, Harmange, Jean-Christophe, Hodge, Kathy, Houk, Brett E., Huang, Xin, Jona, Janan, Joseph, Smriti, Jun, H. Toni, Kumar, Rakesh, Li, Chun, Lu, John, Menges, Tom, Morrison, Michael J., Novak, Perry M., van der Plas, Simon, Radinsky, Robert, Rose, Paul E., Sawant, Satin, Sun, Ji-Rong, Surapaneni, Sekhar, Turci, Susan M., Xu, Keyang, Yanez, Evelyn, Zhao, Huilin, Zhu, Xiaotian
Published in Bioorganic & medicinal chemistry letters (15.04.2011)
Published in Bioorganic & medicinal chemistry letters (15.04.2011)
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Synthesis and pharmacological evaluation of 4a-phenanthrenamine derivatives acting at the phencyclidine binding site of the N-methyl-D-aspartate receptor complex
Bigge, Christopher F, Malone, Thomas C, Hays, Sheryl J, Johnson, Graham, Novak, Perry M, Lescosky, Leonard J, Retz, Daniel M, Ortwine, Daniel F, Probert, Albert W
Published in Journal of medicinal chemistry (01.07.1993)
Published in Journal of medicinal chemistry (01.07.1993)
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Design and synthesis of novel conformationally restricted HIV protease inhibitors
Salituro, Francesco G., Baker, Christopher T., Court, John J., Deininger, David D., Kim, Eunice E., Li, Biquin, Novak, Perry M., Rao, Bhisetti G., Pazhanisamy, S., Porter, Margaret D., Schairer, Wayne C., Tung, Roger D.
Published in Bioorganic & medicinal chemistry letters (15.12.1998)
Published in Bioorganic & medicinal chemistry letters (15.12.1998)
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Synthesis and pharmacological evaluation of hexahydrofluorenamines as noncompetitive antagonists at the N-methyl-D-aspartate receptor
Hays, Sheryl J, Novak, Perry M, Ortwine, Daniel F, Bigge, Christopher F, Colbry, Norman L, Johnson, Graham, Lescosky, Leonard J, Malone, Thomas C, Michael, Andre
Published in Journal of medicinal chemistry (01.03.1993)
Published in Journal of medicinal chemistry (01.03.1993)
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New and versatile approaches to the synthesis of CPP-related competitive NMDA antagonists. Preliminary structure activity relationships and pharmacological evaluation
Hays, Sheryl J, Bigge, Christopher F, Novak, Perry M, Drummond, James T, Bobovski, Thomas P, Rice, Michael J, Johnson, Graham, Brahce, Laura J, Coughenour, Linda L
Published in Journal of medicinal chemistry (01.10.1990)
Published in Journal of medicinal chemistry (01.10.1990)
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Optimization of novel di-substituted cyclohexylbenzamide derivatives as potent 11β-HSD1 inhibitors
McMinn, Dustin L., Rew, Yosup, Sudom, Athena, Caille, Seb, DeGraffenreid, Michael, He, Xiao, Hungate, Randall, Jiang, Ben, Jaen, Juan, Julian, Lisa D., Kaizerman, Jacob, Novak, Perry, Sun, Daqing, Tu, Hua, Ursu, Stefania, Walker, Nigel P.C., Yan, Xuelei, Ye, Qiuping, Wang, Zhulun, Powers, Jay P.
Published in Bioorganic & medicinal chemistry letters (01.03.2009)
Published in Bioorganic & medicinal chemistry letters (01.03.2009)
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UREA DERIVATIVES AS INHIBITORS OF IMPDH ENZYME
BEMIS GUY W, NOVAK PERRY M, BETHIEL RANDY S, RONKIN STEVEN M, SAUNDERS JEFFREY O, ARMISTEAD DAVID M, BADIA MICHAEL C, FRANK CATHARINE A
Year of Publication 15.02.2000
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Year of Publication 15.02.2000
Patent
Design, synthesis, and conformational analysis of a novel series of HIV protease inhibitors
Baker, Christopher T., Salituro, Francesco G., Court, John J., Deininger, David D., Kim, Eunice E., Li, Biquin, Novak, Perry M., Rao, Bhisetti G., Pazhanisamy, S., Schairer, Wayne C., Tung, Roger D.
Published in Bioorganic & medicinal chemistry letters (15.12.1998)
Published in Bioorganic & medicinal chemistry letters (15.12.1998)
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