Novel orally bioavailable EZH1/2 dual inhibitors with greater antitumor efficacy than an EZH2 selective inhibitor
Honma, Daisuke, Kanno, Osamu, Watanabe, Jun, Kinoshita, Junzo, Hirasawa, Makoto, Nosaka, Emi, Shiroishi, Machiko, Takizawa, Takeshi, Yasumatsu, Isao, Horiuchi, Takao, Nakao, Akira, Suzuki, Keisuke, Yamasaki, Tomonori, Nakajima, Katsuyoshi, Hayakawa, Miho, Yamazaki, Takanori, Yadav, Ajay Singh, Adachi, Nobuaki
Published in Cancer science (01.10.2017)
Published in Cancer science (01.10.2017)
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RS-1748, a Novel CC Chemokine Receptor 4 Antagonist, Inhibits Ovalbumin-Induced Airway Inflammation in Guinea Pigs
Nakagami, Yasuhiro, Kawase, Yumi, Yonekubo, Kazuki, Nosaka, Emi, Etori, Maki, Takahashi, Sakiko, Takagi, Nana, Fukuda, Takeshi, Kuribayashi, Takeshi, Nara, Futoshi, Yamashita, Makoto
Published in Biological & Pharmaceutical Bulletin (2010)
Published in Biological & Pharmaceutical Bulletin (2010)
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EZH1/2 Dual Inhibitor Valemetostat Tosylate (DS-3201b) Acts Differently from EZH2 Selective Inhibitor on Epigenetic Landscape to Exert Greater Anti-Tumor Effect Against Diffuse Large B-Cell Lymphoma
Banjo, Toshihiro, Hama, Yasuhiro, Nosaka, Emi, Takata, Yoshimi, Honma, Daisuke, Kitagawa, Mayumi, Yamamoto, Yuka, Wada, Chisa, Yoshida, Takanori, Lim, Kyungtaek, Okamoto, Atsushi, Sato, Erina, Katayama, Yumiko, Sato, Kazumi, Goto, Hiroki, Abe, Yuki
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Anti-Tumor Effect of the EZH1/2 Dual Inhibitor Valemetostat Against Diffuse Large B-Cell Lymphoma Via Modulation of B-Cell Receptor Signaling and c-Myc Signaling Pathways
Hama, Yasuhiro, Banjo, Toshihiro, Honma, Daisuke, Takata, Yoshimi, Nosaka, Emi, Shiroishi, Machiko, Watanabe, Kenji, Yamamoto, Yuka, Hirata, Tsuyoshi, Nakano, Rika, Inaki, Koichiro, Goto, Hiroki, Totoki, Yusuke, Kataoka, Miki, Lim, Kyungtaek, Wada, Chisa, Kumazawa, Eiji, Tsutsumi, Shinji
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Development and Characterization of the Novel Orally Bioavailable EZH1/2 Dual Inhibitor DS-3201
Honma, Daisuke, Adachi, Nobuaki, Kanno, Osamu, Watanabe, Jun, Hirasawa, Makoto, Nosaka, Emi, Shiroishi, Machiko, Takizawa, Takeshi, Yasumatsu, Isao, Horiuchi, Takao, Nakao, Akira, Suzuki, Keisuke, Yamasaki, Tomonori, Nakajima, Katsuyoshi, Hayakawa, Miho, Yamazaki, Takanori, Araki, Kazushi, Fujiwara, Kosaku
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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DS-3201, a Potent EZH1/2 Dual Inhibitor, Demonstrates Antitumor Activity Against Non-Hodgkin Lymphoma (NHL) Regardless of EZH2 Mutation
Honma, Daisuke, Nosaka, Emi, Shiroishi, Machiko, Takata, Yoshimi, Hama, Yasuhiro, Yamamoto, Yuka, Adachi, Nobuaki, Maruyama, Dai, Tobinai, Kensei, Ishida, Takashi, Kusumoto, Shigeru, Ishitsuka, Kenji, Imaizumi, Yoshitaka, Takeuchi, Shogo, Tsukasaki, Kunihiro, Fujioka, Tomoyuki, Watanabe, Jun, Kanno, Osamu, Kumazawa, Eiji, Fujitani, Sumiaki, Araki, Kazushi, Fujiwara, Kosaku
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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