A Tryptoline Ring‐Distortion Strategy Leads to Complex and Diverse Biologically Active Molecules from the Indole Alkaloid Yohimbine
Paciaroni, Nicholas G., Ratnayake, Ranjala, Matthews, James H., Norwood, Verrill M., Arnold, Austin C., Dang, Long H., Luesch, Hendrik, Huigens, Robert W.
Published in Chemistry : a European journal (28.03.2017)
Published in Chemistry : a European journal (28.03.2017)
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Preventing Morphine-Seeking Behavior through the Re-Engineering of Vincamine’s Biological Activity
Norwood, Verrill M, Brice-Tutt, Ariana C, Eans, Shainnel O, Stacy, Heather M, Shi, Guqin, Ratnayake, Ranjala, Rocca, James R, Abboud, Khalil A, Li, Chenglong, Luesch, Hendrik, McLaughlin, Jay P, Huigens, Robert W
Published in Journal of medicinal chemistry (28.05.2020)
Published in Journal of medicinal chemistry (28.05.2020)
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Synthetically Tuning the 2-Position of Halogenated Quinolines: Optimizing Antibacterial and Biofilm Eradication Activities via Alkylation and Reductive Amination Pathways
Basak, Akash, Abouelhassan, Yasmeen, Norwood IV, Verrill M., Bai, Fang, Nguyen, Minh Thu, Jin, Shouguang, Huigens III, Robert W.
Published in Chemistry : a European journal (27.06.2016)
Published in Chemistry : a European journal (27.06.2016)
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Structure–Activity Relationships of a Diverse Class of Halogenated Phenazines That Targets Persistent, Antibiotic-Tolerant Bacterial Biofilms and Mycobacterium tuberculosis
Garrison, Aaron T, Abouelhassan, Yasmeen, Norwood, Verrill M, Kallifidas, Dimitris, Bai, Fang, Nguyen, Minh Thu, Rolfe, Melanie, Burch, Gena M, Jin, Shouguang, Luesch, Hendrik, Huigens, Robert W
Published in Journal of medicinal chemistry (28.04.2016)
Published in Journal of medicinal chemistry (28.04.2016)
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Yohimbine as a Starting Point to Access Diverse Natural Product-Like Agents with Re-programmed Activities against Cancer-Relevant GPCR Targets
Paciaroni, Nicholas G., Norwood, Verrill M., Ratnayake, Ranjala, Luesch, Hendrik, Huigens, Robert W.
Published in Bioorganic & medicinal chemistry (15.07.2020)
Published in Bioorganic & medicinal chemistry (15.07.2020)
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Discovery of quinoline small molecules with potent dispersal activity against methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis biofilms using a scaffold hopping strategy
Abouelhassan, Yasmeen, Garrison, Aaron T., Burch, Gena M., Wong, Wilson, Norwood, Verrill M., Huigens, Robert W.
Published in Bioorganic & medicinal chemistry letters (01.11.2014)
Published in Bioorganic & medicinal chemistry letters (01.11.2014)
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Halogenated quinolines bearing polar functionality at the 2-position: Identification of new antibacterial agents with enhanced activity against Staphylococcus epidermidis
Basak, Akash, Abouelhassan, Yasmeen, Kim, Young S., Norwood, Verrill M., Jin, Shouguang, Huigens, Robert W.
Published in European journal of medicinal chemistry (15.07.2018)
Published in European journal of medicinal chemistry (15.07.2018)
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A Phytochemical-Halogenated Quinoline Combination Therapy Strategy for the Treatment of Pathogenic Bacteria
Abouelhassan, Yasmeen, Garrison, Aaron T., Bai, Fang, Norwood IV, Verrill M., Nguyen, Minh Thu, Jin, Shouguang, Huigens III, Robert W.
Published in ChemMedChem (01.07.2015)
Published in ChemMedChem (01.07.2015)
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Modular Synthetic Routes to Fluorine-Containing Halogenated Phenazine and Acridine Agents That Induce Rapid Iron Starvation in Methicillin-Resistant Staphylococcus aureus Biofilms
Liu, Ke, Brivio, Massimiliano, Xiao, Tao, Kim, Young S, Jin, Shouguang, Papagni, Antonio, Vaghi, Luca
Published in ACS infectious diseases (11.02.2022)
Published in ACS infectious diseases (11.02.2022)
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HFIP in Organic Synthesis
Motiwala, Hashim F., Armaly, Ahlam M., Cacioppo, Jackson G., Coombs, Thomas C., Koehn, Kimberly R. K., Norwood, Verrill M., Aubé, Jeffrey
Published in Chemical reviews (10.08.2022)
Published in Chemical reviews (10.08.2022)
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Re-Engineering of Yohimbine’s Biological Activity through Ring Distortion: Identification and Structure–Activity Relationships of a New Class of Antiplasmodial Agents
Paciaroni, Nicholas G, Perry, David L, Norwood, Verrill M, Murillo-Solano, Claribel, Collins, Jennifer, Tenneti, Srinivasarao, Chakrabarti, Debopam, Huigens, Robert W
Published in ACS infectious diseases (14.02.2020)
Published in ACS infectious diseases (14.02.2020)
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Back Cover: Synthetically Tuning the 2-Position of Halogenated Quinolines: Optimizing Antibacterial and Biofilm Eradication Activities via Alkylation and Reductive Amination Pathways (Chem. Eur. J. 27/2016)
Basak, Akash, Abouelhassan, Yasmeen, Norwood IV, Verrill M., Bai, Fang, Nguyen, Minh Thu, Jin, Shouguang, Huigens III, Robert W.
Published in Chemistry : a European journal (27.06.2016)
Published in Chemistry : a European journal (27.06.2016)
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Journal Article
Back Cover: A Tryptoline Ring‐Distortion Strategy Leads to Complex and Diverse Biologically Active Molecules from the Indole Alkaloid Yohimbine (Chem. Eur. J. 18/2017)
Paciaroni, Nicholas G., Ratnayake, Ranjala, Matthews, James H., Norwood, Verrill M., Arnold, Austin C., Dang, Long H., Luesch, Hendrik, Huigens, Robert W.
Published in Chemistry : a European journal (28.03.2017)
Published in Chemistry : a European journal (28.03.2017)
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Journal Article
Ring Distortion of Vincamine Leads to the Identification of Re-Engineered Antiplasmodial Agents
Murillo-Solano, Claribel, Brummel, Beau R, Perry, David L, Rocca, James R, Chakrabarti, Debopam
Published in ACS omega (10.08.2021)
Published in ACS omega (10.08.2021)
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Microwave-enhanced, stereospecific ring-closure of medium-ring cyanamide ethers to yohimbine
Paciaroni, Nicholas G., Norwood, Verrill M., Garcia, Daniel E., Huigens, Robert W.
Published in Tetrahedron letters (25.04.2019)
Published in Tetrahedron letters (25.04.2019)
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