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Published in Advanced science (01.04.2022)
Published in Advanced science (01.04.2022)
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Cdyl Deficiency Brakes Neuronal Excitability and Nociception through Promoting Kcnb1 Transcription in Peripheral Sensory Neurons
Sun, Zhao‐Wei, Waybright, Jarod M., Beldar, Serap, Chen, Lu, Foley, Caroline A., Norris‐Drouin, Jacqueline L., Lyu, Tian‐Jie, Dong, Aiping, Min, Jinrong, Wang, Yu‐Pu, James, Lindsey I., Wang, Yun
Published in Advanced science (01.09.2023)
Published in Advanced science (01.09.2023)
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Published in Proceedings of the National Academy of Sciences - PNAS (15.10.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.2024)
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Structure–Activity Relationships and Kinetic Studies of Peptidic Antagonists of CBX Chromodomains
Stuckey, Jacob I, Simpson, Catherine, Norris-Drouin, Jacqueline L, Cholensky, Stephanie H, Lee, Junghyun, Pasca, Ryan, Cheng, Nancy, Dickson, Bradley M, Pearce, Kenneth H, Frye, Stephen V, James, Lindsey I
Published in Journal of medicinal chemistry (13.10.2016)
Published in Journal of medicinal chemistry (13.10.2016)
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Design and Construction of a Focused DNA-Encoded Library for Multivalent Chromatin Reader Proteins
Rectenwald, Justin M, Guduru, Shiva Krishna Reddy, Dang, Zhao, Collins, Leonard B, Liao, Yi-En, Norris-Drouin, Jacqueline L, Cholensky, Stephanie H, Kaufmann, Kyle W, Hammond, Scott M, Kireev, Dmitri B, Frye, Stephen V, Pearce, Kenneth H
Published in Molecules (Basel, Switzerland) (22.02.2020)
Published in Molecules (Basel, Switzerland) (22.02.2020)
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Discovery of Peptidomimetic Ligands of EED as Allosteric Inhibitors of PRC2
Barnash, Kimberly D, The, Juliana, Norris-Drouin, Jacqueline L, Cholensky, Stephanie H, Worley, Beau M, Li, Fengling, Stuckey, Jacob I, Brown, Peter J, Vedadi, Masoud, Arrowsmith, Cheryl H, Frye, Stephen V, James, Lindsey I
Published in ACS combinatorial science (13.03.2017)
Published in ACS combinatorial science (13.03.2017)
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Discovery of hit compounds for methyl-lysine reader proteins from a target class DNA-encoded library
Shell, Devan J., Rectenwald, Justin M., Buttery, Peter H., Johnson, Rebecca L., Foley, Caroline A., Guduru, Shiva K.R., Uguen, Mélanie, Rubiano, Juanita Sanchez, Zhang, Xindi, Li, Fengling, Norris-Drouin, Jacqueline L., Axtman, Matthew, Brian Hardy, P., Vedadi, Masoud, Frye, Stephen V., James, Lindsey I., Pearce, Kenneth H.
Published in SLAS discovery (01.12.2022)
Published in SLAS discovery (01.12.2022)
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Discovery of Potent Peptidomimetic Antagonists for Heterochromatin Protein 1 Family Proteins
Lamb, Kelsey N, Dishman, Sarah N, Waybright, Jarod M, Engelberg, Isabelle A, Rectenwald, Justin M, Norris-Drouin, Jacqueline L, Cholensky, Stephanie H, Pearce, Kenneth H, James, Lindsey I, Frye, Stephen V
Published in ACS omega (11.01.2022)
Published in ACS omega (11.01.2022)
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Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader
Potjewyd, Frances, Turner, Anne-Marie W., Beri, Joshua, Rectenwald, Justin M., Norris-Drouin, Jacqueline L., Cholensky, Stephanie H., Margolis, David M., Pearce, Kenneth H., Herring, Laura E., James, Lindsey I.
Published in Cell chemical biology (16.01.2020)
Published in Cell chemical biology (16.01.2020)
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Identification of Covalent Cyclic Peptide Inhibitors in mRNA Display
Iskandar, Sabrina E., Chiou, Lilly F., Leisner, Tina M., Shell, Devan J., Norris-Drouin, Jacqueline L., Vaziri, Cyrus, Pearce, Kenneth H., Bowers, Albert A.
Published in Journal of the American Chemical Society (19.07.2023)
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Discovery of CHD1 Antagonists for PTEN-Deficient Prostate Cancer
Johnson, Rebecca L., Graboski, Amanda L., Li, Fengling, Norris-Drouin, Jacqueline L., Walton, William G., Arrowsmith, Cheryl H., Redinbo, Matthew R., Frye, Stephen V., James, Lindsey I.
Published in Journal of medicinal chemistry (28.11.2024)
Published in Journal of medicinal chemistry (28.11.2024)
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Discovery and Structural Basis of the Selectivity of Potent Cyclic Peptide Inhibitors of MAGE-A4
Fleming, Matthew C., Chiou, Lilly F., Tumbale, Percy P., Droby, Gaith N., Lim, Jiwoong, Norris-Drouin, Jacqueline L., Williams, Jason G., Pearce, Kenneth H., Williams, R. Scott, Vaziri, Cyrus, Bowers, Albert A.
Published in Journal of medicinal chemistry (26.05.2022)
Published in Journal of medicinal chemistry (26.05.2022)
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Discovery of an H3K36me3-Derived Peptidomimetic Ligand with Enhanced Affinity for Plant Homeodomain Finger Protein 1 (PHF1)
Engelberg, Isabelle A, Liu, Jiuyang, Norris-Drouin, Jacqueline L, Cholensky, Stephanie H, Ottavi, Samantha A, Frye, Stephen V, Kutateladze, Tatiana G, James, Lindsey I
Published in Journal of medicinal chemistry (24.06.2021)
Published in Journal of medicinal chemistry (24.06.2021)
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Discovery of a 53BP1 Small Molecule Antagonist Using a Focused DNA-Encoded Library Screen
Shell, Devan J., Foley, Caroline A., Wang, Qinhong, Smith, Chelsea M., Guduru, Shiva K. R., Zeng, Hong, Dong, Aiping, Norris-Drouin, Jacqueline L., Axtman, Matthew, Hardy, P. Brian, Gupta, Gaorav, Halabelian, Levon, Frye, Stephen V., James, Lindsey I., Pearce, Kenneth H.
Published in Journal of medicinal chemistry (26.10.2023)
Published in Journal of medicinal chemistry (26.10.2023)
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PROTAC Linkerology Leads to an Optimized Bivalent Chemical Degrader of Polycomb Repressive Complex 2 (PRC2) Components
Bashore, Frances M., Foley, Caroline A., Ong, Han Wee, Rectenwald, Justin M., Hanley, Ronan P., Norris-Drouin, Jacqueline L., Cholensky, Stephanie H., Mills, Christine A., Pearce, Kenneth H., Herring, Laura E., Kireev, Dmitri, Frye, Stephen V., James, Lindsey I.
Published in ACS chemical biology (17.03.2023)
Published in ACS chemical biology (17.03.2023)
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SETDB1 Triple Tudor Domain Ligand, (R,R)‑59, Promotes Methylation of Akt1 in Cells
Uguen, Mélanie, Deng, Yu, Li, Fengling, Shell, Devan J., Norris-Drouin, Jacqueline L., Stashko, Michael A., Ackloo, Suzanne, Arrowsmith, Cheryl H., James, Lindsey I., Liu, Pengda, Pearce, Kenneth H., Frye, Stephen V.
Published in ACS chemical biology (18.08.2023)
Published in ACS chemical biology (18.08.2023)
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A Peptidomimetic Ligand Targeting the Chromodomain of MPP8 Reveals HRP2’s Association with the HUSH Complex
Waybright, Jarod M, Clinkscales, Sarah E, Barnash, Kimberly D, Budziszewski, Gabrielle R, Rectenwald, Justin M, Chiarella, Anna M, Norris-Drouin, Jacqueline L, Cholensky, Stephanie H, Pearce, Kenneth H, Herring, Laura E, McGinty, Robert K, Hathaway, Nathaniel A, James, Lindsey I
Published in ACS chemical biology (17.09.2021)
Published in ACS chemical biology (17.09.2021)
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Discovery and Characterization of Peptide Inhibitors for Calcium and Integrin Binding Protein 1
Puhl, Ana C, Bogart, Jonathan W, Haberman, Victoria A, Larson, Jacob E, Godoy, Andre S, Norris-Drouin, Jacqueline L, Cholensky, Stephanie H, Leisner, Tina M, Frye, Stephen V, Parise, Leslie V, Bowers, Albert A, Pearce, Kenneth H
Published in ACS chemical biology (19.06.2020)
Published in ACS chemical biology (19.06.2020)
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Quantitative Characterization of Bivalent Probes for a Dual Bromodomain Protein, Transcription Initiation Factor TFIID Subunit 1
Suh, Junghyun L, Watts, Brian, Stuckey, Jacob I, Norris-Drouin, Jacqueline L, Cholensky, Stephanie H, Dickson, Bradley M, An, Yi, Mathea, Sebastian, Salah, Eidarus, Knapp, Stefan, Khan, Abid, Adams, Alexander T, Strahl, Brian D, Sagum, Cari A, Bedford, Mark T, James, Lindsey I, Kireev, Dmitri B, Frye, Stephen V
Published in Biochemistry (Easton) (10.04.2018)
Published in Biochemistry (Easton) (10.04.2018)
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