Deep Generative Models of LDLR Protein Structure to Predict Variant Pathogenicity
James, Jose K., Norland, Kristjan, Johar, Angad S., Kullo, Iftikhar J.
Published in Journal of lipid research (01.12.2023)
Published in Journal of lipid research (01.12.2023)
Get full text
Journal Article
Sequence variants with large effects on cardiac electrophysiology and disease
Norland, Kristjan, Sveinbjornsson, Gardar, Thorolfsdottir, Rosa B, Davidsson, Olafur B, Tragante, Vinicius, Rajamani, Sridharan, Helgadottir, Anna, Gretarsdottir, Solveig, van Setten, Jessica, Asselbergs, Folkert W, Sverrisson, Jon Th, Stephensen, Sigurdur S, Oskarsson, Gylfi, Sigurdsson, Emil L, Andersen, Karl, Danielsen, Ragnar, Thorgeirsson, Gudmundur, Thorsteinsdottir, Unnur, Arnar, David O, Sulem, Patrick, Holm, Hilma, Gudbjartsson, Daniel F, Stefansson, Kari
Published in Nature communications (22.10.2019)
Published in Nature communications (22.10.2019)
Get full text
Journal Article
Predicting the probability of death using proteomics
Eiriksdottir, Thjodbjorg, Ardal, Steinthor, Jonsson, Benedikt A., Lund, Sigrun H., Ivarsdottir, Erna V., Norland, Kristjan, Ferkingstad, Egil, Stefansson, Hreinn, Jonsdottir, Ingileif, Holm, Hilma, Rafnar, Thorunn, Saemundsdottir, Jona, Norddahl, Gudmundur L., Thorgeirsson, Gudmundur, Gudbjartsson, Daniel F., Sulem, Patrick, Thorsteinsdottir, Unnur, Stefansson, Kari, Ulfarsson, Magnus O.
Published in Communications biology (18.06.2021)
Published in Communications biology (18.06.2021)
Get full text
Journal Article
Screening for Rare Coding Variants That Associate With the QTc Interval in Iceland
Sveinbjornsson, Gardar, Benediktsdottir, Bara D, Sigfusson, Gunnlaugur, Norland, Kristjan, Davidsson, Olafur B, Thorolfsdottir, Rosa B, Tragante, Vinicius, Arnadottir, Gudny A, Jensson, Brynjar O, Katrinardottir, Hildigunnur, Fridriksdottir, Run, Gudmundsdottir, Hallbera, Aegisdottir, Hildur M, Fridriksson, Brynjar, Thorgeirsson, Gudmundur, Magnusson, Vidar, Oddsson, Asmundur, Sulem, Patrick, Gudbjartsson, Daniel F, Holm, Hilma, Arnar, David O, Stefansson, Kari
Published in Journal of the American Heart Association (18.07.2023)
Published in Journal of the American Heart Association (18.07.2023)
Get full text
Journal Article
Sense of Security Mediates the Relationship Between Self-care Behavior and Health Status of Patients With Heart Failure: A Cross-sectional Study
Ingadottir, Brynja, Jaarsma, Tiny, Norland, Kristján, Ketilsdóttir, Auður
Published in The Journal of cardiovascular nursing (01.11.2023)
Published in The Journal of cardiovascular nursing (01.11.2023)
Get more information
Journal Article
PLEIOTROPIC EFFECTS OF THE JAK2V617F MUTATION: A PHEWAS AND LABWAS STUDY
Teymourzadeh, Azin, Norland, Kristjan, Kullo, Iftikhar J.
Published in Journal of the American College of Cardiology (02.04.2024)
Published in Journal of the American College of Cardiology (02.04.2024)
Get full text
Journal Article
A SCORE INCORPORATING SOCIAL-DETERMINANTS-OF-HEALTH AND LIFESTYLE FACTORS OUTPERFORMS A POLYGENIC RISK SCORE IN PREDICTING INCIDENT CORONARY HEART DISEASE
Naderian, Mohammadreza, Norland, Kristjan, Kullo, Iftikhar J.
Published in Journal of the American College of Cardiology (02.04.2024)
Published in Journal of the American College of Cardiology (02.04.2024)
Get full text
Journal Article
ASSOCIATION OF A POLYGENIC RISK SCORE FOR CORONARY HEART DISEASE WITH ANGIOGRAPHIC CORONARY ARTERY DISEASE WITH ANGIOGRAPHIC CORONARY ARTERY DISEASE SEVERITY
Sherafati, Alborz, Norland, Kristjan, Kullo, Iftikhar J.
Published in Journal of the American College of Cardiology (07.03.2023)
Published in Journal of the American College of Cardiology (07.03.2023)
Get full text
Journal Article
Multiomics study of nonalcoholic fatty liver disease
Sveinbjornsson, Gardar, Ulfarsson, Magnus O, Thorolfsdottir, Rosa B, Jonsson, Benedikt A, Einarsson, Eythor, Gunnlaugsson, Gylfi, Rognvaldsson, Solvi, Arnar, David O, Baldvinsson, Magnus, Bjarnason, Ragnar G, Eiriksdottir, Thjodbjorg, Erikstrup, Christian, Ferkingstad, Egil, Halldorsson, Gisli H, Helgason, Hannes, Helgadottir, Anna, Hindhede, Lotte, Hjorleifsson, Grimur, Jones, David, Knowlton, Kirk U, Lund, Sigrun H, Melsted, Pall, Norland, Kristjan, Olafsson, Isleifur, Olafsson, Sigurdur, Oskarsson, Gudjon R, Ostrowski, Sisse Rye, Pedersen, Ole Birger, Snaebjarnarson, Auðunn S, Sigurdsson, Emil, Steinthorsdottir, Valgerdur, Schwinn, Michael, Thorgeirsson, Gudmundur, Thorleifsson, Gudmar, Jonsdottir, Ingileif, Bundgaard, Henning, Nadauld, Lincoln, Bjornsson, Einar S, Rulifson, Ingrid C, Rafnar, Thorunn, Norddahl, Gudmundur L, Thorsteinsdottir, Unnur, Sulem, Patrick, Gudbjartsson, Daniel F, Holm, Hilma, Stefansson, Kari
Published in Nature genetics (01.11.2022)
Published in Nature genetics (01.11.2022)
Get full text
Journal Article
Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis
Styrkarsdottir, Unnur, Lund, Sigrun H, Thorleifsson, Gudmar, Zink, Florian, Stefansson, Olafur A, Sigurdsson, Jon K, Juliusson, Kristinn, Bjarnadottir, Kristbjörg, Sigurbjornsdottir, Sara, Jonsson, Stefan, Norland, Kristjan, Stefansdottir, Lilja, Sigurdsson, Asgeir, Sveinbjornsson, Gardar, Oddsson, Asmundur, Bjornsdottir, Gyda, Gudmundsson, Reynir L, Halldorsson, Gisli H, Rafnar, Thorunn, Jonsdottir, Ingileif, Steingrimsson, Eirikur, Norddahl, Gudmundur L, Masson, Gisli, Sulem, Patrick, Jonsson, Helgi, Ingvarsson, Thorvaldur, Gudbjartsson, Daniel F, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature genetics (01.12.2018)
Published in Nature genetics (01.12.2018)
Get full text
Journal Article
Abstract 10360: Polygenic Risk Score, Rare Monogenic Variants, and Family History Have Independent and Additive Effects on the Risk of Coronary Heart Disease
Saadatagah, Seyedmohammad, Hamed, Marwan, Miller, Alexandra, Bangash, Hana, Nigbur, Scott, Kamzabek, Arailym, Norland, Kristjan, Kosel, Matt, Schaid, Daniel, Kullo, Iftikhar J
Published in Circulation (New York, N.Y.) (08.11.2022)
Published in Circulation (New York, N.Y.) (08.11.2022)
Get full text
Journal Article
Eighty-eight variants highlight the role of T cell regulation and airway remodeling in asthma pathogenesis
Olafsdottir, Thorunn A, Theodors, Fannar, Bjarnadottir, Kristbjorg, Bjornsdottir, Unnur Steina, Agustsdottir, Arna B, Stefansson, Olafur A, Ivarsdottir, Erna V, Sigurdsson, Jon K, Benonisdottir, Stefania, Eyjolfsson, Gudmundur I, Gislason, David, Gislason, Thorarinn, Guðmundsdóttir, Steinunn, Gylfason, Arnaldur, Halldorsson, Bjarni V, Halldorsson, Gisli H, Juliusdottir, Thorhildur, Kristinsdottir, Anna M, Ludviksdottir, Dora, Ludviksson, Bjorn R, Masson, Gisli, Norland, Kristjan, Onundarson, Pall T, Olafsson, Isleifur, Sigurdardottir, Olof, Stefansdottir, Lilja, Sveinbjornsson, Gardar, Tragante, Vinicius, Gudbjartsson, Daniel F, Thorleifsson, Gudmar, Sulem, Patrick, Thorsteinsdottir, Unnur, Norddahl, Gudmundur L, Jonsdottir, Ingileif, Stefansson, Kari
Published in Nature communications (20.01.2020)
Published in Nature communications (20.01.2020)
Get full text
Journal Article
Loss-of-Function Variants in the Tumor-Suppressor Gene PTPN14 Confer Increased Cancer Risk
Olafsdottir, Thorhildur, Stacey, Simon N, Sveinbjornsson, Gardar, Thorleifsson, Gudmar, Norland, Kristjan, Sigurgeirsson, Bardur, Thorisdottir, Kristin, Kristjansson, Arni Kjalar, Tryggvadottir, Laufey, Sarin, Kavita Y, Benediktsson, Rafn, Jonasson, Jon G, Sigurdsson, Asgeir, Jonasdottir, Aslaug, Kristmundsdottir, Snaedis, Jonsson, Hakon, Gylfason, Arnaldur, Oddsson, Asmundur, Fridriksdottir, Run, Gudjonsson, Sigurjon A, Zink, Florian, Lund, Sigrun H, Rognvaldsson, Solvi, Melsted, Pall, Steinthorsdottir, Valgerdur, Gudmundsson, Julius, Mikaelsdottir, Evgenia, Olason, Pall I, Stefansdottir, Lilja, Eggertsson, Hannes P, Halldorsson, Bjarni V, Thorsteinsdottir, Unnur, Agustsson, Tomas T, Olafsson, Karl, Olafsson, Jon H, Sulem, Patrick, Rafnar, Thorunn, Gudbjartsson, Daniel F, Stefansson, Kari
Published in Cancer research (Chicago, Ill.) (15.04.2021)
Published in Cancer research (Chicago, Ill.) (15.04.2021)
Get full text
Journal Article
Genetic variants associated with platelet count are predictive of human disease and physiological markers
Mikaelsdottir, Evgenia, Thorleifsson, Gudmar, Stefansdottir, Lilja, Halldorsson, Gisli, Sigurdsson, Jon K, Lund, Sigrun H, Tragante, Vinicius, Melsted, Pall, Rognvaldsson, Solvi, Norland, Kristjan, Helgadottir, Anna, Magnusson, Magnus K, Ragnarsson, Gunnar B, Kristinsson, Sigurdur Y, Reykdal, Sigrun, Vidarsson, Brynjar, Gudmundsdottir, Ingibjorg J, Olafsson, Isleifur, Onundarson, Pall T, Sigurdardottir, Olof, Sigurdsson, Emil L, Grondal, Gerdur, Geirsson, Arni J, Geirsson, Gudmundur, Gudmundsson, Julius, Holm, Hilma, Saevarsdottir, Saedis, Jonsdottir, Ingileif, Thorgeirsson, Gudmundur, Gudbjartsson, Daniel F, Thorsteinsdottir, Unnur, Rafnar, Thorunn, Stefansson, Kari
Published in Communications biology (27.09.2021)
Published in Communications biology (27.09.2021)
Get full text
Journal Article
Genetic architecture of band neutrophil fraction in Iceland
Oskarsson, Gudjon R, Magnusson, Magnus K, Oddsson, Asmundur, Jensson, Brynjar O, Fridriksdottir, Run, Arnadottir, Gudny A, Katrinardottir, Hildigunnur, Rognvaldsson, Solvi, Halldorsson, Gisli H, Sveinbjornsson, Gardar, Ivarsdottir, Erna V, Stefansdottir, Lilja, Ferkingstad, Egil, Norland, Kristjan, Tragante, Vinicius, Saemundsdottir, Jona, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Sigurjonsdottir, Svanhvit, Petursdottir, Karen O, Davidsson, Olafur B, Rafnar, Thorunn, Holm, Hilma, Olafsson, Isleifur, Onundarson, Pall T, Vidarsson, Brynjar, Sigurdardottir, Olof, Masson, Gisli, Gudbjartsson, Daniel F, Jonsdottir, Ingileif, Norddahl, Gudmundur L, Thorsteinsdottir, Unnur, Sulem, Patrick, Stefansson, Kari
Published in Communications biology (01.06.2022)
Published in Communications biology (01.06.2022)
Get full text
Journal Article
Joint Association of Polygenic Risk and Social Determinants of Health with Coronary Heart Disease in the United States
Norland, Kristjan, Schaid, Daniel J, Naderian, Mohammadreza, Na, Jie, Kullo, Iftikhar J
Published in medRxiv : the preprint server for health sciences (11.01.2024)
Published in medRxiv : the preprint server for health sciences (11.01.2024)
Get more information
Journal Article
Admix-kit: an integrated toolkit and pipeline for genetic analyses of admixed populations
Hou, Kangcheng, Gogarten, Stephanie, Kim, Joohyun, Hua, Xing, Dias, Julie-Alexia, Sun, Quan, Wang, Ying, Tan, Taotao, Atkinson, Elizabeth G, Martin, Alicia, Shortt, Jonathan, Hirbo, Jibril, Li, Yun, Pasaniuc, Bogdan, Zhang, Haoyu
Published in Bioinformatics (Oxford, England) (29.03.2024)
Published in Bioinformatics (Oxford, England) (29.03.2024)
Get full text
Journal Article
The sequences of 150,119 genomes in the UK biobank
Halldorsson, Bjarni V, Eggertsson, Hannes P, Moore, Kristjan Hs, Hauswedell, Hannes, Eiriksson, Ogmundur, Ulfarsson, Magnus O, Palsson, Gunnar, Hardarson, Marteinn T, Oddsson, Asmundur, Jensson, Brynjar O, Kristmundsdottir, Snaedis, Sigurpalsdottir, Brynja D, Stefansson, Olafur A, Beyter, Doruk, Holley, Guillaume, Tragante, Vinicius, Gylfason, Arnaldur, Olason, Pall I, Zink, Florian, Asgeirsdottir, Margret, Sverrisson, Sverrir T, Sigurdsson, Brynjar, Gudjonsson, Sigurjon A, Sigurdsson, Gunnar T, Halldorsson, Gisli H, Sveinbjornsson, Gardar, Norland, Kristjan, Styrkarsdottir, Unnur, Magnusdottir, Droplaug N, Snorradottir, Steinunn, Kristinsson, Kari, Sobech, Emilia, Thorleifsson, Gudmar, Jonsson, Frosti, Melsted, Pall, Jonsdottir, Ingileif, Rafnar, Thorunn, Holm, Hilma, Stefansson, Hreinn, Jona Saemundsdottir, Gudbjartsson, Daniel F, Magnusson, Olafur T, Masson, Gisli, Thorsteinsdottir, Unnur, Helgason, Agnar, Jonsson, Hakon, Sulem, Patrick, Stefansson, Kari, Jonsson, Helgi, Arni Jon Geirsson, Olafsson, Isleifur, Jonsson, Palmi, Pedersen, Ole Birger, Erikstrup, Christian, Brunak, Soren, Ostrowski, Sisse Rye
Published in bioRxiv (01.03.2022)
Published in bioRxiv (01.03.2022)
Get full text
Paper