Regioselective hydroxylation of steroid hormones by human cytochromes P450
Niwa, Toshiro, Murayama, Norie, Imagawa, Yurie, Yamazaki, Hiroshi
Published in Drug metabolism reviews (01.05.2015)
Published in Drug metabolism reviews (01.05.2015)
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Journal Article
Molecular and functional characterization of cytosolic sulfotransferases in cynomolgus macaque
Uno, Yasuhiro, Murayama, Norie, Yamazaki, Hiroshi
Published in Biochemical pharmacology (01.08.2019)
Published in Biochemical pharmacology (01.08.2019)
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Journal Article
Genetic variants of N-acetyltransferases 1 and 2 (NAT1 and NAT2) in cynomolgus and rhesus macaques
Uno, Yasuhiro, Murayama, Norie, Yamazaki, Hiroshi
Published in Biochemical pharmacology (01.07.2020)
Published in Biochemical pharmacology (01.07.2020)
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Journal Article
Modeled Hepatic/Plasma Exposures of Omeprazole Prescribed Alone in Cytochrome P450 2C19 Poor Metabolizers Are Likely Associated with Hepatic Toxicity Reported in a Japanese Adverse Event Database
Adachi, Koichiro, Ohyama, Katsuhiro, Tanaka, Yoichi, Murayama, Norie, Shimizu, Makiko, Saito, Yoshiro, Yamazaki, Hiroshi
Published in Biological & pharmaceutical bulletin (24.05.2024)
Published in Biological & pharmaceutical bulletin (24.05.2024)
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Journal Article
Molecular and Functional Characterization of N‑Acetyltransferases NAT1 and NAT2 in Cynomolgus Macaque
Uno, Yasuhiro, Murayama, Norie, Yamazaki, Hiroshi
Published in Chemical research in toxicology (19.11.2018)
Published in Chemical research in toxicology (19.11.2018)
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Journal Article
Refined CYP2E1∗ Template∗∗ system to decipher the ligand-interactions
Yamazoe, Yasushi, Murayama, Norie, Yoshinari, Kouichi
Published in Drug metabolism and pharmacokinetics (01.12.2021)
Published in Drug metabolism and pharmacokinetics (01.12.2021)
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Journal Article
Voriconazole Metabolism, Toxicity, and the Effect of Cytochrome P450 2C19 Genotype
Zonios, Dimitrios, Yamazaki, Hiroshi, Murayama, Norie, Natarajan, Ven, Palmore, Tara, Childs, Richard, Skinner, Jeff, Bennett, John E.
Published in The Journal of infectious diseases (15.06.2014)
Published in The Journal of infectious diseases (15.06.2014)
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Journal Article
Cytochrome P450 1A1, 2C9, 2C19, and 3A4 Polymorphisms Account for Interindividual Variability of Toxicological Drug Metabolism in Cynomolgus Macaques
Uno, Yasuhiro, Uehara, Shotaro, Murayama, Norie, Yamazaki, Hiroshi
Published in Chemical research in toxicology (17.12.2018)
Published in Chemical research in toxicology (17.12.2018)
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Journal Article
Genetic variants of aldehyde oxidase (AOX) 1 in cynomolgus and rhesus macaques
Uno, Yasuhiro, Uehara, Shotaro, Murayama, Norie, Yamazaki, Hiroshi
Published in Xenobiotica (03.04.2021)
Published in Xenobiotica (03.04.2021)
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Journal Article
Cytochrome P450 1A2 and 2C enzymes autoinduced by omeprazole in dog hepatocytes and human HepaRG and HepaSH cells are involved in omeprazole 5-hydroxylation and sulfoxidation
Uno, Yasuhiro, Uehara, Shotaro, Ushirozako, Genki, Murayama, Norie, Suemizu, Hiroshi, Yamazaki, Hiroshi
Published in Xenobiotica (03.07.2023)
Published in Xenobiotica (03.07.2023)
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Metabolic profiles for the pyrrolizidine alkaloid neopetasitenine and its metabolite petasitenine in humans extrapolated from rat in vivo and in vitro data sets using a simplified physiologically based pharmacokinetic model
Yanagi, Mayu, Kamiya, Yusuke, Murayama, Norie, Banju, Kaito, Shimizu, Makiko, Yamazaki, Hiroshi
Published in Journal of toxicological sciences (2021)
Published in Journal of toxicological sciences (2021)
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Journal Article
A comprehensive analysis of six forms of cytochrome P450 2C (CYP2C) in pigs
Uno, Yasuhiro, Morikuni, Saho, Shiraishi, Mitsuya, Asano, Atsushi, Kawaguchi, Hiroaki, Murayama, Norie, Yamazaki, Hiroshi
Published in Xenobiotica (02.11.2022)
Published in Xenobiotica (02.11.2022)
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Journal Article
Plasma and Hepatic Exposures of Celecoxib and Diclofenac Prescribed Alone in Patients with Cytochrome P450 2C93 Modeled after Virtual Oral Administrations and Likely Associated with Adverse Drug Events Reported in a Japanese Database
Adachi, Koichiro, Ohyama, Katsuhiro, Tanaka, Yoichi, Nakano, Hina, Sato, Tasuku, Murayama, Norie, Shimizu, Makiko, Saito, Yoshiro, Yamazaki, Hiroshi
Published in Biological & pharmaceutical bulletin (01.06.2023)
Published in Biological & pharmaceutical bulletin (01.06.2023)
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Journal Article
Newly identified cytochrome P450 3A genes of tree shrews and pigs are expressed and encode functional enzymes
Uno, Yasuhiro, Jikuya, Shiori, Noda, Yutaro, Oguchi, Asuka, Murayama, Norie, Kawaguchi, Hiroaki, Tsukiyama-Kohara, Kyoko, Yamazaki, Hiroshi
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01.05.2023)
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01.05.2023)
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Journal Article
Molecular and Functional Characterization of N -Acetyltransferases in Common Marmosets and Pigs
Uno, Yasuhiro, Uehara, Shotaro, Ijiri, Moe, Kawaguchi, Hiroaki, Asano, Atsushi, Shiraishi, Mitsuya, Banju, Kaito, Murayama, Norie, Yamazaki, Hiroshi
Published in Drug metabolism and disposition (01.11.2022)
Published in Drug metabolism and disposition (01.11.2022)
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