Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties
Nordin, Joel Z., M.D, Lee, Yi, BSc, Vader, Pieter, PhD, Mäger, Imre, PhD, Johansson, Henrik J., PhD, Heusermann, Wolf, PhD, Wiklander, Oscar P.B., M.D, Hällbrink, Mattias, PhD, Seow, Yiqi, DPhil, Bultema, Jarred J., PhD, Gilthorpe, Jonathan, PhD, Davies, Tim, MSc, Fairchild, Paul J., PhD, Gabrielsson, Susanne, PhD, Meisner-Kober, Nicole C., PhD, Lehtiö, Janne, PhD, Smith, C.I. Edvard, M.D., PhD, Wood, Matthew J.A., M.D., DPhil, Andaloussi, Samir EL, PhD
Published in Nanomedicine (01.05.2015)
Published in Nanomedicine (01.05.2015)
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Journal Article
Identification of scaffold proteins for improved endogenous engineering of extracellular vesicles
Zheng, Wenyi, Rädler, Julia, Sork, Helena, Niu, Zheyu, Roudi, Samantha, Bost, Jeremy P, Görgens, André, Zhao, Ying, Mamand, Doste R, Liang, Xiuming, Wiklander, Oscar P B, Lehto, Taavi, Gupta, Dhanu, Nordin, Joel Z, El Andaloussi, Samir
Published in Nature communications (07.08.2023)
Published in Nature communications (07.08.2023)
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Journal Article
Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome
Sork, Helena, Corso, Giulia, Krjutskov, Kaarel, Johansson, Henrik J, Nordin, Joel Z, Wiklander, Oscar P B, Lee, Yi Xin Fiona, Westholm, Jakub Orzechowski, Lehtiö, Janne, Wood, Matthew J A, Mäger, Imre, El Andaloussi, Samir
Published in Scientific reports (17.07.2018)
Published in Scientific reports (17.07.2018)
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Journal Article
Systematic Methodological Evaluation of a Multiplex Bead-Based Flow Cytometry Assay for Detection of Extracellular Vesicle Surface Signatures
Wiklander, Oscar P B, Bostancioglu, R Beklem, Welsh, Joshua A, Zickler, Antje M, Murke, Florian, Corso, Giulia, Felldin, Ulrika, Hagey, Daniel W, Evertsson, Björn, Liang, Xiu-Ming, Gustafsson, Manuela O, Mohammad, Dara K, Wiek, Constanze, Hanenberg, Helmut, Bremer, Michel, Gupta, Dhanu, Björnstedt, Mikael, Giebel, Bernd, Nordin, Joel Z, Jones, Jennifer C, El Andaloussi, Samir, Görgens, André
Published in Frontiers in immunology (13.06.2018)
Published in Frontiers in immunology (13.06.2018)
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Journal Article
Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting
Wiklander, Oscar P. B., Nordin, Joel Z., O'Loughlin, Aisling, Gustafsson, Ylva, Corso, Giulia, Mäger, Imre, Vader, Pieter, Lee, Yi, Sork, Helena, Seow, Yiqi, Heldring, Nina, Alvarez-Erviti, Lydia, Smith, CI Edvard, Le Blanc, Katarina, Macchiarini, Paolo, Jungebluth, Philipp, Wood, Matthew J. A., Andaloussi, Samir EL
Published in Journal of extracellular vesicles (01.01.2015)
Published in Journal of extracellular vesicles (01.01.2015)
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Journal Article
Quantification of extracellular vesicles in vitro and in vivo using sensitive bioluminescence imaging
Gupta, Dhanu, Liang, Xiuming, Pavlova, Svetlana, Wiklander, Oscar P.B, Corso, Giulia, Zhao, Ying, Saher, Osama, Bost, Jeremy, Zickler, Antje M., Piffko, Andras, Maire, Cecile L., Ricklefs, Franz L., Gustafsson, Oskar, Llorente, Virginia Castilla, Gustafsson, Manuela O., Bostancioglu, R. Beklem, Mamand, Doste R, Hagey, Daniel W., Görgens, André, Nordin, Joel Z., EL Andaloussi, Samir
Published in Journal of extracellular vesicles (01.01.2020)
Published in Journal of extracellular vesicles (01.01.2020)
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Journal Article
Extracellular vesicles as the next‐generation modulators of pharmacokinetics and pharmacodynamics of medications and their potential as adjuvant therapeutics
Liu, Jiaqi, Nordin, Joel Z., McLachlan, Andrew J., Chrzanowski, Wojciech
Published in Clinical and translational medicine (01.08.2024)
Published in Clinical and translational medicine (01.08.2024)
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Journal Article
Efficient Peptide-Mediated In Vitro Delivery of Cas9 RNP
Gustafsson, Oskar, Rädler, Julia, Roudi, Samantha, Lehto, Tõnis, Hällbrink, Mattias, Lehto, Taavi, Gupta, Dhanu, Andaloussi, Samir EL, Nordin, Joel Z.
Published in Pharmaceutics (14.06.2021)
Published in Pharmaceutics (14.06.2021)
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Journal Article
Systemic exosomal siRNA delivery reduced alpha-synuclein aggregates in brains of transgenic mice
Cooper, J. Mark, Wiklander, P.B. Oscar, Nordin, Joel Z., Al-Shawi, Raya, Wood, Matthew J., Vithlani, Mansi, Schapira, Anthony H. V., Simons, J. Paul, El-Andaloussi, Samir, Alvarez-Erviti, Lydia
Published in Movement disorders (01.10.2014)
Published in Movement disorders (01.10.2014)
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Journal Article
Lipidomic Analyses Reveal Specific Alterations of Phosphatidylcholine in Dystrophic Mdx Muscle
Valentine, William J, Mostafa, Sherif A, Tokuoka, Suzumi M, Hamano, Fumie, Inagaki, Natsuko F, Nordin, Joel Z, Motohashi, Norio, Kita, Yoshihiro, Aoki, Yoshitsugu, Shimizu, Takao, Shindou, Hideo
Published in Frontiers in physiology (12.01.2022)
Published in Frontiers in physiology (12.01.2022)
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Journal Article
Extracellular vesicles engineered to bind albumin demonstrate extended circulation time and lymph node accumulation in mouse models
Liang, Xiuming, Niu, Zheyu, Galli, Valentina, Howe, Nathalie, Zhao, Ying, Wiklander, Oscar P. B., Zheng, Wenyi, Wiklander, Rim Jawad, Corso, Giulia, Davies, Christopher, Hean, Justin, Kyriakopoulou, Eleni, Mamand, Doste R., Amin, Risul, Nordin, Joel Z., Gupta, Dhanu, Andaloussi, Samir EL
Published in Journal of extracellular vesicles (01.07.2022)
Published in Journal of extracellular vesicles (01.07.2022)
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Journal Article
Extracellular vesicles are the primary source of blood‐borne tumour‐derived mutant KRAS DNA early in pancreatic cancer
Hagey, Daniel W., Kordes, Maximilian, Görgens, André, Mowoe, Metoboroghene O., Nordin, Joel Z., Moro, Carlos Fernández, Löhr, J.‐Matthias, EL Andaloussi, Samir
Published in Journal of extracellular vesicles (01.10.2021)
Published in Journal of extracellular vesicles (01.10.2021)
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Journal Article
Characterizing Exon Skipping Efficiency in DMD Patient Samples in Clinical Trials of Antisense Oligonucleotides
Nordin, Joel Z, Mizobe, Yoshitaka, Nakamura, Harumasa, Komaki, Hirofumi, Takeda, Shin'ichi, Aoki, Yoshitsugu
Published in Journal of visualized experiments (07.05.2020)
Published in Journal of visualized experiments (07.05.2020)
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Journal Article
Serum-free culture alters the quantity and protein composition of neuroblastoma-derived extracellular vesicles
Li, Jinghuan, Lee, Yi, Johansson, Henrik J., Mäger, Imre, Vader, Pieter, Nordin, Joel Z., Wiklander, Oscar P. B., Lehtiö, Janne, Wood, Matthew J. A., Andaloussi, Samir EL
Published in Journal of extracellular vesicles (01.01.2015)
Published in Journal of extracellular vesicles (01.01.2015)
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Journal Article
Extracellular vesicles originating from melanoma cells promote dysregulation in haematopoiesis as a component of cancer immunoediting
Mamand, Doste R., Bazaz, Safa, Mohammad, Dara K., Liang, Xiuming, Pavlova, Svetlana, Mim, Carsten, Gabrielsson, Susanne, Nordin, Joel Z., Wiklander, Oscar P. B., Abedi‐Valugerdi, Manuchehr, EL‐Andaloussi, Samir
Published in Journal of extracellular vesicles (01.07.2024)
Published in Journal of extracellular vesicles (01.07.2024)
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Journal Article
Fine Tuning of Phosphorothioate Inclusion in 2′-O-Methyl Oligonucleotides Contributes to Specific Cell Targeting for Splice-Switching Modulation
Aoki, Yoshitsugu, Rocha, Cristina S. J., Lehto, Taavi, Miyatake, Shouta, Johansson, Henrik, Hashimoto, Yasumasa, Nordin, Joel Z., Mager, Imre, Aoki, Misako, Graham, McClorey, Sathyaprakash, Chaitra, Roberts, Thomas C., Wood, Matthew J. A., Behlke, Mark A., Andaloussi, Samir El
Published in Frontiers in physiology (13.10.2021)
Published in Frontiers in physiology (13.10.2021)
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Journal Article
Reproducible and scalable purification of extracellular vesicles using combined bind-elute and size exclusion chromatography
Corso, Giulia, Mäger, Imre, Lee, Yi, Görgens, André, Bultema, Jarred, Giebel, Bernd, Wood, Matthew J A, Nordin, Joel Z, Andaloussi, Samir El
Published in Scientific reports (14.09.2017)
Published in Scientific reports (14.09.2017)
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