Clonal expansion of early to mid-life mitochondrial DNA point mutations drives mitochondrial dysfunction during human ageing
Greaves, Laura C, Nooteboom, Marco, Elson, Joanna L, Tuppen, Helen A L, Taylor, Geoffrey A, Commane, Daniel M, Arasaradnam, Ramesh P, Khrapko, Konstantin, Taylor, Robert W, Kirkwood, Thomas B L, Mathers, John C, Turnbull, Douglass M
Published in PLoS genetics (01.09.2014)
Published in PLoS genetics (01.09.2014)
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Comparison of mitochondrial mutation spectra in ageing human colonic epithelium and disease: absence of evidence for purifying selection in somatic mitochondrial DNA point mutations
Greaves, Laura C, Elson, Joanna L, Nooteboom, Marco, Grady, John P, Taylor, Geoffrey A, Taylor, Robert W, Mathers, John C, Kirkwood, Thomas B L, Turnbull, Doug M
Published in PLoS genetics (01.11.2012)
Published in PLoS genetics (01.11.2012)
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Controlling T‑Cell Activation with Synthetic Dendritic Cells Using the Multivalency Effect
Hammink, Roel, Mandal, Subhra, Eggermont, Loek J, Nooteboom, Marco, Willems, Peter H. G. M, Tel, Jurjen, Rowan, Alan E, Figdor, Carl G, Blank, Kerstin G
Published in ACS omega (31.03.2017)
Published in ACS omega (31.03.2017)
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Regulation and quantification of cellular mitochondrial morphology and content
Tronstad, Karl J, Nooteboom, Marco, Nilsson, Linn I H, Nikolaisen, Julie, Sokolewicz, Maciek, Grefte, Sander, Pettersen, Ina K N, Dyrstad, Sissel, Hoel, Fredrik, Willems, Peter H G M, Koopman, Werner J H
Published in Current pharmaceutical design (01.01.2014)
Published in Current pharmaceutical design (01.01.2014)
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BOLA1 is an aerobic protein that prevents mitochondrial morphology changes induced by glutathione depletion
Willems, Peter, Wanschers, Bas F J, Esseling, John, Szklarczyk, Radek, Kudla, Urszula, Duarte, Isabel, Forkink, Marleen, Nooteboom, Marco, Swarts, Herman, Gloerich, Jolein, Nijtmans, Leo, Koopman, Werner, Huynen, Martijn A
Published in Antioxidants & redox signaling (10.01.2013)
Published in Antioxidants & redox signaling (10.01.2013)
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A mutation in the FAM36A gene, the human ortholog of COX20, impairs cytochrome c oxidase assembly and is associated with ataxia and muscle hypotonia
Szklarczyk, Radek, Wanschers, Bas F J, Nijtmans, Leo G, Rodenburg, Richard J, Zschocke, Johannes, Dikow, Nicola, van den Brand, Mariël A M, Hendriks-Franssen, Marthe G M, Gilissen, Christian, Veltman, Joris A, Nooteboom, Marco, Koopman, Werner J H, Willems, Peter H G M, Smeitink, Jan A M, Huynen, Martijn A, van den Heuvel, Lambertus P
Published in Human molecular genetics (15.02.2013)
Published in Human molecular genetics (15.02.2013)
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Age‐associated mitochondrial DNA mutations lead to small but significant changes in cell proliferation and apoptosis in human colonic crypts
Nooteboom, Marco, Johnson, Riem, Taylor, Robert W., Wright, Nicholas A., Lightowlers, Robert N., Kirkwood, Thomas B. L., Mathers, John C., Turnbull, Doug M., Greaves, Laura C.
Published in Aging cell (01.02.2010)
Published in Aging cell (01.02.2010)
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Mitochondrial DNA mutations affect calcium handling in differentiated neurons
Trevelyan, Andrew J., Kirby, Denise M., Smulders-Srinivasan, Tora K., Nooteboom, Marco, Acin-Perez, Rebeca, Enriquez, José Antonio, Whittington, Miles A., Lightowlers, Robert N., Turnbull, Doug M.
Published in Brain (London, England : 1878) (01.03.2010)
Published in Brain (London, England : 1878) (01.03.2010)
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Clonal Expansion of Early to Mid-Life Mitochondrial DNA Point Mutations Drives Mitochondrial Dysfunction during Human Ageing: e1004620
Greaves, Laura C, Nooteboom, Marco, Elson, Joanna L, Tuppen, Helen AL, Taylor, Geoffrey A, Commane, Daniel M, Arasaradnam, Ramesh P, Khrapko, Konstantin, Taylor, Robert W, Kirkwood, Thomas BL, Mathers, John C, Turnbull, Douglass M
Published in PLoS genetics (01.09.2014)
Published in PLoS genetics (01.09.2014)
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Quantitative Glucose and ATP Sensing in Mammalian Cells: Mitochondrial Delivery of Biologically Active Molecules
LIEMBURG-APERS, Dania C, IMAMURA, Hiromi, FORKINK, Marleen, NOOTEBOOM, Marco, SWARTS, Herman G, BROCK, Roland, SMEITINK, Jan A. M, WILLEMS, Peter H. G. M, KOOPMAN, Werner J. H
Published in Pharmaceutical research (2011)
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Published in Pharmaceutical research (2011)
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