Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78
Gorbatyuk, Marina. S., Knox, Tessa, LaVail, Matthew M., Gorbatyuk, Oleg S., Noorwez, Syed M., Hauswirth, William W., Lin, Jonathan H., Muzyczka, Nicholas, Lewin, Alfred S., Berns, Kenneth I.
Published in Proceedings of the National Academy of Sciences - PNAS (30.03.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (30.03.2010)
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Journal Article
Pharmacological Chaperone-mediated in Vivo Folding and Stabilization of the P23H-opsin Mutant Associated with Autosomal Dominant Retinitis Pigmentosa
Noorwez, Syed M., Kuksa, Vladimir, Imanishi, Yoshikazu, Zhu, Li, Filipek, Sławomir, Palczewski, Krzysztof, Kaushal, Shalesh
Published in The Journal of biological chemistry (18.04.2003)
Published in The Journal of biological chemistry (18.04.2003)
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Journal Article
Photoactivation-induced instability of rhodopsin mutants T4K and T17M in rod outer segments underlies retinal degeneration in X. laevis transgenic models of retinitis pigmentosa
Tam, Beatrice M, Noorwez, Syed M, Kaushal, Shalesh, Kono, Masahiro, Moritz, Orson L
Published in The Journal of neuroscience (01.10.2014)
Published in The Journal of neuroscience (01.10.2014)
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Journal Article
Gene therapy restores vision-dependent behavior as well as retinal structure and function in a mouse model of RPE65 Leber congenital amaurosis
Pang, Ji-jing, Chang, Bo, Kumar, Ashok, Nusinowitz, Steven, Noorwez, Syed M, Li, Jie, Rani, Asha, Foster, Thomas C, Chiodo, Vince A, Doyle, Thomas, Li, Huashi, Malhotra, Ritu, Teusner, Jacqueline T, McDowell, J Hugh, Min, Seok-Hong, Li, Qiuhong, Kaushal, Shalesh, Hauswirth, William W
Published in Molecular therapy (01.03.2006)
Published in Molecular therapy (01.03.2006)
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Journal Article
Retinal degeneration 12 (rd12): a new, spontaneously arising mouse model for human Leber congenital amaurosis (LCA)
Pang, Ji-Jing, Chang, Bo, Hawes, Norman L, Hurd, Ronald E, Davisson, Muriel T, Li, Jie, Noorwez, Syed M, Malhotra, Ritu, McDowell, J Hugh, Kaushal, Shalesh, Hauswirth, William W, Nusinowitz, Steven, Thompson, Debra A, Heckenlively, John R
Published in Molecular vision (28.02.2005)
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Published in Molecular vision (28.02.2005)
Journal Article
Quality control of integral membrane proteins
Krebs, Mark P., Noorwez, Syed M., Malhotra, Ritu, Kaushal, Shalesh
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.12.2004)
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.12.2004)
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Journal Article
Gene Therapy Restores Vision-Dependent Behavior as Well as Retinal Structure and Function in a Mouse Model of RPE65 Leber Congenital Amaurosis
Pang, Ji-jing, Chang, Bo, Kumar, Ashok, Nusinowitz, Steven, Noorwez, Syed M., Li, Jie, Rani, Asha, Foster, Thomas C., Chiodo, Vince A., Doyle, Thomas, Li, Huashi, Malhotra, Ritu, Teusner, Jacqueline T., McDowell, J. Hugh, Min, Seok-Hong, Li, Qiuhong, Kaushal, Shalesh, Hauswirth, William W.
Published in Molecular therapy (01.03.2006)
Published in Molecular therapy (01.03.2006)
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Journal Article
Pharmacological chaperone-mediated in vivo folding and stabilization of the P23H-opsin mutant associated with autosomal dominant retinitis pigmentosa
Noorwez, Syed M., Kuksa, Vladimir, Imanishi, Yoshikazu, Zhu, Li, Filipek, Sławomir, Palczewski, Krzysztof, Kaushal, Shalesh
Published in The Journal of biological chemistry (06.06.2003)
Published in The Journal of biological chemistry (06.06.2003)
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Journal Article
Stabilized mutant opsin proteins
Palczewski Krzysztof, Kuksa Vladimir, Kaushal Shalesh, Noorwez Syed M
Year of Publication 06.03.2018
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Year of Publication 06.03.2018
Patent
STABILIZED MUTANT OPSIN PROTEINS
NOORWEZ SYED M, PALCZEWSKI KRZYSZTOF, KUKSA VLADIMIR, KAUSHAL SHALESH
Year of Publication 18.02.2016
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Year of Publication 18.02.2016
Patent
Stabilized mutant opsin proteins
NOORWEZ SYED M, PALCZEWSKI KRZYSZTOF, KUKSA VLADIMIR, KAUSHAL SHALESH
Year of Publication 06.10.2015
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Year of Publication 06.10.2015
Patent
STABILIZED MUTANT OPSIN PROTEINS
NOORWEZ SYED M, PALCZEWSKI KRZYSZTOF, KUKSA VLADIMIR, KAUSHAL SHALESH
Year of Publication 21.03.2013
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Year of Publication 21.03.2013
Patent
STABILIZED MUTANT OPSIN PROTEINS
NOORWEZ SYED M, PALCZEWSKI KRZYSZTOF, KUKSA VLADIMIR, KAUSHAL SHALESH
Year of Publication 16.02.2012
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Year of Publication 16.02.2012
Patent
Stabilized mutant opsin proteins
NOORWEZ SYED M, PALCZEWSKI KRZYSZTOF, KUKSA VLADIMIR, KAUSHAL SHALESH
Year of Publication 02.12.2004
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Year of Publication 02.12.2004
Patent