Metabolic Engineering toward Sustainable Production of Nylon‑6
Turk, Stefan C. H. J, Kloosterman, Wigard P, Ninaber, Dennis K, Kolen, Karin P. A. M, Knutova, Julia, Suir, Erwin, Schürmann, Martin, Raemakers-Franken, Petronella C, Müller, Monika, de Wildeman, Stefaan M. A, Raamsdonk, Leonie M, van der Pol, Ruud, Wu, Liang, Temudo, Margarida F, van der Hoeven, Rob A. M, Akeroyd, Michiel, van der Stoel, Roland E, Noorman, Henk J, Bovenberg, Roel A. L, Trefzer, Axel C
Published in ACS synthetic biology (15.01.2016)
Published in ACS synthetic biology (15.01.2016)
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Grand Research Challenges for Sustainable Industrial Biotechnology
Straathof, Adrie J.J, Wahl, S. Aljoscha, Benjamin, Kirsten R, Takors, Ralf, Wierckx, Nick, Noorman, Henk J
Published in Trends in biotechnology (Regular ed.) (01.10.2019)
Published in Trends in biotechnology (Regular ed.) (01.10.2019)
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Computational fluid dynamics simulation of an industrial P. chrysogenum fermentation with a coupled 9-pool metabolic model: Towards rational scale-down and design optimization
Haringa, Cees, Tang, Wenjun, Wang, Guan, Deshmukh, Amit T., van Winden, Wouter A., Chu, Ju, van Gulik, Walter M., Heijnen, Joseph J., Mudde, Robert F., Noorman, Henk J.
Published in Chemical engineering science (2018)
Published in Chemical engineering science (2018)
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Euler-Lagrange computational fluid dynamics for (bio)reactor scale down: An analysis of organism lifelines
Haringa, Cees, Tang, Wenjun, Deshmukh, Amit T., Xia, Jianye, Reuss, Matthias, Heijnen, Joseph J., Mudde, Robert F., Noorman, Henk J.
Published in Engineering in life sciences (01.10.2016)
Published in Engineering in life sciences (01.10.2016)
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Quantitative metabolomics and metabolic flux analysis reveal impact of altered trehalose metabolism on metabolic phenotypes of Penicillium chrysogenum in aerobic glucose-limited chemostats
Wang, Guan, Zhao, Junfei, Wang, Xinxin, Wang, Tong, Zhuang, Yingping, Chu, Ju, Zhang, Siliang, Noorman, Henk J.
Published in Biochemical engineering journal (15.06.2019)
Published in Biochemical engineering journal (15.06.2019)
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A 9‐pool metabolic structured kinetic model describing days to seconds dynamics of growth and product formation by Penicillium chrysogenum
Tang, Wenjun, Deshmukh, Amit T., Haringa, Cees, Wang, Guan, van Gulik, Walter, van Winden, Wouter, Reuss, Matthias, Heijnen, Joseph J., Xia, Jianye, Chu, Ju, Noorman, Henk J.
Published in Biotechnology and bioengineering (01.08.2017)
Published in Biotechnology and bioengineering (01.08.2017)
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Towards closed carbon loop fermentations: Cofeeding of Yarrowia lipolytica with glucose and formic acid
van Winden, Wouter A., Mans, Robert, Breestraat, Stefaan, Verlinden, Rob A. J., Mielgo‐Gómez, Álvaro, de Hulster, Erik A. F., de Bruijn, Hans M. C. J., Noorman, Henk J.
Published in Biotechnology and bioengineering (01.08.2022)
Published in Biotechnology and bioengineering (01.08.2022)
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Power input effects on degeneration in prolonged penicillin chemostat cultures: A systems analysis at flux, residual glucose, metabolite, and transcript levels
Wang, Guan, Wu, Baofeng, Zhao, Junfei, Haringa, Cees, Xia, Jianye, Chu, Ju, Zhuang, Yingping, Zhang, Siliang, Heijnen, Joseph J., van Gulik, Walter, Deshmukh, Amit T., Noorman, Henk J.
Published in Biotechnology and bioengineering (01.01.2018)
Published in Biotechnology and bioengineering (01.01.2018)
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Journal Article
Comparative Fluxome and Metabolome Analysis of Formate as an Auxiliary Substrate for Penicillin Production in Glucose-Limited Cultivation of Penicillium chrysogenum
Wang, Guan, Wang, Xinxin, Wang, Tong, van Gulik, Walter, Noorman, Henk J, Zhuang, Yingping, Chu, Ju, Zhang, Siliang
Published in Biotechnology journal (01.10.2019)
Published in Biotechnology journal (01.10.2019)
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Comparative performance of different scale‐down simulators of substrate gradients in Penicillium chrysogenum cultures: the need of a biological systems response analysis
Wang, Guan, Zhao, Junfei, Haringa, Cees, Tang, Wenjun, Xia, Jianye, Chu, Ju, Zhuang, Yingping, Zhang, Siliang, Deshmukh, Amit T., Gulik, Walter, Heijnen, Joseph J., Noorman, Henk J.
Published in Microbial biotechnology (01.05.2018)
Published in Microbial biotechnology (01.05.2018)
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Metabolic-fluid dynamics model construction and scale-down design for an industrial penicillin chrysogenum fermentation with combined dissolved oxygen and glucose concentration dynamics
Wei, Peng, Haringa, Cees, Portela, Luis M., Noorman, Henk J.
Published in Chemical engineering science (15.07.2023)
Published in Chemical engineering science (15.07.2023)
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From industrial fermentor to CFD-guided downscaling: what have we learned?
Haringa, Cees, Mudde, Robert F., Noorman, Henk J.
Published in Biochemical engineering journal (15.12.2018)
Published in Biochemical engineering journal (15.12.2018)
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High-resolution computation predicts that low dissolved CO concentrations and CO gradients promote ethanol production at industrial-scale gas fermentation
Puiman, Lars, Almeida Benalcázar, Eduardo, Picioreanu, Cristian, Noorman, Henk J., Haringa, Cees
Published in Biochemical engineering journal (01.07.2024)
Published in Biochemical engineering journal (01.07.2024)
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