Tryptophan Metabolism in Inflammaging: From Biomarker to Therapeutic Target
Sorgdrager, Freek J H, Naudé, Petrus J W, Kema, Ido P, Nollen, Ellen A, Deyn, Peter P De
Published in Frontiers in immunology (30.10.2019)
Published in Frontiers in immunology (30.10.2019)
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An open-source platform for analyzing and sharing worm-behavior data
Javer, Avelino, Currie, Michael, Lee, Chee Wai, Hokanson, Jim, Li, Kezhi, Martineau, Céline N., Yemini, Eviatar, Grundy, Laura J., Li, Chris, Ch’ng, QueeLim, Schafer, William R., Nollen, Ellen A. A., Kerr, Rex, Brown, André E. X.
Published in Nature methods (01.09.2018)
Published in Nature methods (01.09.2018)
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Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation
van der Goot, Annemieke T, Zhu, Wentao, Vázquez-Manrique, Rafael P, Seinstra, Renée I, Dettmer, Katja, Michels, Helen, Farina, Francesca, Krijnen, Jasper, Melki, Ronald, Buijsman, Rogier C, Ruiz Silva, Mariana, Thijssen, Karen L, Kema, Ido P, Neri, Christian, Oefner, Peter J, Nollen, Ellen A. A
Published in Proceedings of the National Academy of Sciences - PNAS (11.09.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (11.09.2012)
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Assessing motor-related phenotypes of Caenorhabditis elegans with the wide field-of-view nematode tracking platform
Koopman, Mandy, Peter, Quentin, Seinstra, Renée I., Perni, Michele, Vendruscolo, Michele, Dobson, Christopher M., Knowles, Tuomas P. J., Nollen, Ellen A. A.
Published in Nature protocols (01.06.2020)
Published in Nature protocols (01.06.2020)
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Journal Article
Multistep Inhibition of α‑Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine
Perni, Michele, Flagmeier, Patrick, Limbocker, Ryan, Cascella, Roberta, Aprile, Francesco A, Galvagnion, Céline, Heller, Gabriella T, Meisl, Georg, Chen, Serene W, Kumita, Janet R, Challa, Pavan K, Kirkegaard, Julius B, Cohen, Samuel I. A, Mannini, Benedetta, Barbut, Denise, Nollen, Ellen A. A, Cecchi, Cristina, Cremades, Nunilo, Knowles, Tuomas P. J, Chiti, Fabrizio, Zasloff, Michael, Vendruscolo, Michele, Dobson, Christopher M
Published in ACS chemical biology (17.08.2018)
Published in ACS chemical biology (17.08.2018)
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Transcriptomics-Based Screening Identifies Pharmacological Inhibition of Hsp90 as a Means to Defer Aging
Janssens, Georges E., Lin, Xin-Xuan, Millan-Ariño, Lluís, Kavšek, Alan, Sen, Ilke, Seinstra, Renée I., Stroustrup, Nicholas, Nollen, Ellen A.A., Riedel, Christian G.
Published in Cell reports (Cambridge) (09.04.2019)
Published in Cell reports (Cambridge) (09.04.2019)
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Extracellular 4′-phosphopantetheine is a source for intracellular coenzyme A synthesis
Srinivasan, Balaji, Baratashvili, Madina, van der Zwaag, Marianne, Kanon, Bart, Colombelli, Cristina, Lambrechts, Roald A, Schaap, Onno, Nollen, Ellen A, Podgoršek, Ajda, Kosec, Gregor, Petković, Hrvoje, Hayflick, Susan, Tiranti, Valeria, Reijngoud, Dirk-Jan, Grzeschik, Nicola A, Sibon, Ody C M
Published in Nature chemical biology (01.10.2015)
Published in Nature chemical biology (01.10.2015)
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A screening-based platform for the assessment of cellular respiration in Caenorhabditis elegans
Koopman, Mandy, Michels, Helen, Dancy, Beverley M, Kamble, Rashmi, Mouchiroud, Laurent, Auwerx, Johan, Nollen, Ellen A A, Houtkooper, Riekelt H
Published in Nature protocols (01.10.2016)
Published in Nature protocols (01.10.2016)
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Journal Article
Cellular Regulation of Amyloid Formation in Aging and Disease
Stroo, Esther, Koopman, Mandy, Nollen, Ellen A A, Mata-Cabana, Alejandro
Published in Frontiers in neuroscience (14.02.2017)
Published in Frontiers in neuroscience (14.02.2017)
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Journal Article
A FRET Sensor for Non-Invasive Imaging of Amyloid Formation in Vivo
Kaminski Schierle, Gabriele S., Bertoncini, Carlos W., Chan, Fiona T. S., van der Goot, Annemieke T., Schwedler, Stefanie, Skepper, Jeremy, Schlachter, Simon, van Ham, Tjakko, Esposito, Alessandro, Kumita, Janet R., Nollen, Ellen A. A., Dobson, Christopher M., Kaminski, Clemens F.
Published in Chemphyschem (25.02.2011)
Published in Chemphyschem (25.02.2011)
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Regulation of Age-Related Protein Toxicity
Pras, Anita, Nollen, Ellen A A
Published in Frontiers in cell and developmental biology (05.03.2021)
Published in Frontiers in cell and developmental biology (05.03.2021)
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Journal Article
Polyglutamine protein aggregates are dynamic
Morimoto, Richard I, Kim, Soojin, Nollen, Ellen A. A, Kitagawa, Kazunori, Bindokas, Vytautas P
Published in Nature cell biology (01.10.2002)
Published in Nature cell biology (01.10.2002)
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Journal Article
SERF Protein Is a Direct Modifier of Amyloid Fiber Assembly
Falsone, S. Fabio, Meyer, N. Helge, Schrank, Evelyne, Leitinger, Gerd, Pham, Chi L.L., Fodero-Tavoletti, Michelle T., Holmberg, Mats, Dulle, Martin, Scicluna, Benjamin, Gesslbauer, Bernd, Rückert, Hanna-Marie, Wagner, Gabriel E., Merle, David A., Nollen, Ellen A., Kungl, Andreas J., Hill, Andrew F., Cappai, Roberto, Zangger, Klaus
Published in Cell reports (Cambridge) (30.08.2012)
Published in Cell reports (Cambridge) (30.08.2012)
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Journal Article
Genome-Wide RNA Interference Screen Identifies Previously Undescribed Regulators of Polyglutamine Aggregation
Ellen A. A. Nollen, Garcia, Susana M., van Haaften, Gijs, Kim, Soojin, Chavez, Alejandro, Morimoto, Richard I., Ronald H. A. Plasterk, Horwich, A. L.
Published in Proceedings of the National Academy of Sciences - PNAS (27.04.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (27.04.2004)
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Proteome-wide Changes in Protein Turnover Rates in C. elegans Models of Longevity and Age-Related Disease
Visscher, Marieke, De Henau, Sasha, Wildschut, Mattheus H.E., van Es, Robert M., Dhondt, Ineke, Michels, Helen, Kemmeren, Patrick, Nollen, Ellen A., Braeckman, Bart P., Burgering, Boudewijn M.T., Vos, Harmjan R., Dansen, Tobias B.
Published in Cell reports (Cambridge) (13.09.2016)
Published in Cell reports (Cambridge) (13.09.2016)
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Journal Article
Age‐ and disease‐specific changes of the kynurenine pathway in Parkinson’s and Alzheimer’s disease
Sorgdrager, Freek J. H., Vermeiren, Yannick, Faassen, Martijn, Ley, Claude, Nollen, Ellen A. A., Kema, Ido P., De Deyn, Peter P.
Published in Journal of neurochemistry (01.12.2019)
Published in Journal of neurochemistry (01.12.2019)
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