Metabolic reprogramming during the Trypanosoma brucei life cycle
Smith, Terry K., Bringaud, Frédéric, Nolan, Derek P., Figueiredo, Luisa M.
Published in F1000 research (2017)
Published in F1000 research (2017)
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Mechanism of Trypanosoma brucei gambiense resistance to human serum
Uzureau, Pierrick, Uzureau, Sophie, Lecordier, Laurence, Fontaine, Frédéric, Tebabi, Patricia, Homblé, Fabrice, Grélard, Axelle, Zhendre, Vanessa, Nolan, Derek P., Lins, Laurence, Crowet, Jean-Marc, Pays, Annette, Felu, Cécile, Poelvoorde, Philippe, Vanhollebeke, Benoit, Moestrup, Soren K., Lyngsø, Jeppe, Pedersen, Jan Skov, Mottram, Jeremy C., Dufourc, Erick J., Pérez-Morga, David, Pays, Etienne
Published in Nature (London) (19.09.2013)
Published in Nature (London) (19.09.2013)
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Coupling of lysosomal and mitochondrial membrane permeabilization in trypanolysis by APOL1
Vanwalleghem, Gilles, Fontaine, Frédéric, Lecordier, Laurence, Tebabi, Patricia, Klewe, Kristoffer, Nolan, Derek P., Yamaryo-Botté, Yoshiki, Botté, Cyrille, Kremer, Anneke, Burkard, Gabriela Schumann, Rassow, Joachim, Roditi, Isabel, Pérez-Morga, David, Pays, Etienne
Published in Nature communications (26.08.2015)
Published in Nature communications (26.08.2015)
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Detailed Biological Profiling of a Photoactivated and Apoptosis Inducing pdppz Ruthenium(II) Polypyridyl Complex in Cancer Cells
Cloonan, Suzanne M, Elmes, Robert B. P, Erby, MariaLuisa, Bright, Sandra A, Poynton, Fergus E, Nolan, Derek E, Quinn, Susan J, Gunnlaugsson, Thorfinnur, Williams, D. Clive
Published in Journal of medicinal chemistry (11.06.2015)
Published in Journal of medicinal chemistry (11.06.2015)
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Vinyl Sulfone-Based Peptidomimetics as Anti-Trypanosomal Agents: Design, Synthesis, Biological and Computational Evaluation
Dunny, Elizabeth, Doherty, William, Evans, Paul, Malthouse, J. Paul G, Nolan, Derek, Knox, Andrew J. S
Published in Journal of medicinal chemistry (12.09.2013)
Published in Journal of medicinal chemistry (12.09.2013)
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The Trypanosome-Derived Metabolite Indole-3-Pyruvate Inhibits Prostaglandin Production in Macrophages by Targeting COX2
Diskin, Ciana, Corcoran, Sarah E., Tyrrell, Victoria J., McGettrick, Anne F., Zaslona, Zbigniew, O’Donnell, Valerie B., Nolan, Derek P., O’Neill, Luke A. J.
Published in The Journal of immunology (1950) (15.11.2021)
Published in The Journal of immunology (1950) (15.11.2021)
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Trypanosoma brucei Secreted Aromatic Ketoacids Activate the Nrf2/HO-1 Pathway and Suppress Pro-inflammatory Responses in Primary Murine Glia and Macrophages
Campbell, Nicole K, Williams, David G, Fitzgerald, Hannah K, Barry, Paul J, Cunningham, Clare C, Nolan, Derek P, Dunne, Aisling
Published in Frontiers in immunology (11.09.2019)
Published in Frontiers in immunology (11.09.2019)
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Queuine Micronutrient Deficiency Promotes Warburg Metabolism and Reversal of the Mitochondrial ATP Synthase in Hela Cells
Hayes, Patti, Fergus, Claire, Ghanim, Magda, Cirzi, Cansu, Burtnyak, Lyubomyr, McGrenaghan, Callum J, Tuorto, Francesca, Nolan, Derek P, Kelly, Vincent P
Published in Nutrients (24.03.2020)
Published in Nutrients (24.03.2020)
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Trypanosoma brucei metabolite indolepyruvate decreases HIF-1α and glycolysis in macrophages as a mechanism of innate immune evasion
McGettrick, Anne F., Corcoran, Sarah E., Barry, Paul J. G., McFarland, Jennifer, Crès, Cécile, Curtis, Anne M., Franklin, Edward, Corr, Sinéad C., Mok, K. Hun, Cummins, Eoin P., Taylor, Cormac T., O’Neill, Luke A. J., Nolan, Derek P.
Published in Proceedings of the National Academy of Sciences - PNAS (29.11.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (29.11.2016)
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The trypanolytic factor of human serum
Pays, Etienne, Vanhollebeke, Benoit, Vanhamme, Luc, Paturiaux-Hanocq, Françoise, Nolan, Derek P, Pérez-Morga, David
Published in Nature reviews. Microbiology (01.06.2006)
Published in Nature reviews. Microbiology (01.06.2006)
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Apolipoprotein L-I is the trypanosome lytic factor of human serum
Pays, Etienne, Vanhamme, Luc, Paturiaux-Hanocq, Françoise, Poelvoorde, Philippe, Nolan, Derek P, Lins, Laurence, Van Den Abbeele, Jan, Pays, Annette, Tebabi, Patricia, Van Xong, Huang, Jacquet, Alain, Moguilevsky, Nicole, Dieu, Marc, Kane, John P, De Baetselier, Patrick, Brasseur, Robert
Published in Nature (London) (06.03.2003)
Published in Nature (London) (06.03.2003)
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Identification and characterization of an unusual class I myosin involved in vesicle traffic in Trypanosoma brucei
Spitznagel, Diana, O'Rourke, John F, Leddy, Neal, Hanrahan, Orla, Nolan, Derek P
Published in PloS one (19.08.2010)
Published in PloS one (19.08.2010)
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Glucose-induced Remodeling of Intermediary and Energy Metabolism in Procyclic Trypanosoma brucei
Coustou, Virginie, Biran, Marc, Breton, Marc, Guegan, Fabien, Rivière, Loïc, Plazolles, Nicolas, Nolan, Derek, Barrett, Michael P., Franconi, Jean-Michel, Bringaud, Frédéric
Published in The Journal of biological chemistry (13.06.2008)
Published in The Journal of biological chemistry (13.06.2008)
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The Trypanosoma Brucei KIFC1 Kinesin Ensures the Fast Antibody Clearance Required for Parasite Infectivity
Lecordier, Laurence, Uzureau, Sophie, Vanwalleghem, Gilles, Deleu, Magali, Crowet, Jean-Marc, Barry, Paul, Moran, Barry, Voorheis, Paul, Dumitru, Andra-Cristina, Yamaryo-Botté, Yoshiki, Dieu, Marc, Tebabi, Patricia, Vanhollebeke, Benoit, Lins, Laurence, Botté, Cyrille Y., Alsteens, David, Dufrêne, Yves, Pérez-Morga, David, Nolan, Derek P., Pays, Etienne
Published in iScience (25.09.2020)
Published in iScience (25.09.2020)
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The Trypanosoma brucei -Derived Ketoacids, Indole Pyruvate and Hydroxyphenylpyruvate, Induce HO-1 Expression and Suppress Inflammatory Responses in Human Dendritic Cells
Fitzgerald, Hannah K, O'Rourke, Sinead A, Desmond, Eva, Neto, Nuno G B, Monaghan, Michael G, Tosetto, Miriam, Doherty, Jayne, Ryan, Elizabeth J, Doherty, Glen A, Nolan, Derek P, Fletcher, Jean M, Dunne, Aisling
Published in Antioxidants (15.01.2022)
Published in Antioxidants (15.01.2022)
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Inhibition of late-stage autophagy synergistically enhances pyrrolo-1,5-benzoxazepine-6-induced apoptotic cell death in human colon cancer cells
GREENE, LISA M, NOLAN, DEREK P, REGAN-KOMITO, DANIEL, CAMPIANI, GIUSEPPE, WILLIAMS, D. CLIVE, ZISTERER, DANIELA M
Published in International journal of oncology (01.09.2013)
Published in International journal of oncology (01.09.2013)
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A differential role for actin during the life cycle of Trypanosoma brucei
García-Salcedo, José A, Pérez-Morga, David, Gijón, Purificación, Dilbeck, Vincent, Pays, Etienne, Nolan, Derek P
Published in The EMBO journal (25.02.2004)
Published in The EMBO journal (25.02.2004)
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