Selective Activation of M4 Muscarinic Acetylcholine Receptors Reverses MK-801-Induced Behavioral Impairments and Enhances Associative Learning in Rodents
Bubser, Michael, Bridges, Thomas M, Dencker, Ditte, Gould, Robert W, Grannan, Michael, Noetzel, Meredith J, Lamsal, Atin, Niswender, Colleen M, Daniels, J. Scott, Poslusney, Michael S, Melancon, Bruce J, Tarr, James C, Byers, Frank W, Wess, Jürgen, Duggan, Mark E, Dunlop, John, Wood, Michael W, Brandon, Nicholas J, Wood, Michael R, Lindsley, Craig W, Conn, P. Jeffrey, Jones, Carrie K
Published in ACS chemical neuroscience (15.10.2014)
Published in ACS chemical neuroscience (15.10.2014)
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Challenges in the development of an M-4 PAM in vivo tool compound: The discovery of VU0467154 and unexpected DMPK profiles of close analogs
Wood, Michael R., Noetzel, Meredith J., Poslusney, Michael S., Melancon, Bruce J., Tarr, James C., Lamsal, Atin, Chang, Sichen, Luscombe, Vincent B., Weiner, Rebecca L., Cho, Hyekyung P., Bubser, Michael, Jones, Carrie K., Niswender, Colleen M., Wood, Michael W., Engers, Darren W., Brandon, Nicholas J., Duggan, Mark E., Conn, P. Jeffrey, Bridges, Thomas M., Lindsley, Craig W.
Published in Bioorganic & medicinal chemistry letters (15.01.2017)
Published in Bioorganic & medicinal chemistry letters (15.01.2017)
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Journal Article
Challenges in the development of an M-4 PAM preclinical candidate: The discovery, SAR, and in vivo characterization of a series of 3-aminoazetidine-derived amides
Tarr, James C., Wood, Michael R., Noetzel, Meredith J., Bertron, Jeanette L., Weiner, Rebecca L., Rodriguez, Alice L., Lamsal, Atin, Byers, Frank W., Chang, Sichen, Cho, Hyekyung P., Jones, Carrie K., Niswender, Colleen M., Wood, Michael W., Brandon, Nicholas J., Duggan, Mark E., Conn, P. Jeffrey, Bridges, Thomas M., Lindsley, Craig W.
Published in Bioorganic & medicinal chemistry letters (01.07.2017)
Published in Bioorganic & medicinal chemistry letters (01.07.2017)
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Journal Article
Controlled Trial of Transfusions for Silent Cerebral Infarcts in Sickle Cell Anemia
DeBaun, Michael R, Gordon, Mae, McKinstry, Robert C, Noetzel, Michael J, White, Desiree A, Sarnaik, Sharada A, Meier, Emily R, Howard, Thomas H, Majumdar, Suvankar, Inusa, Baba P.D, Telfer, Paul T, Kirby-Allen, Melanie, McCavit, Timothy L, Kamdem, Annie, Airewele, Gladstone, Woods, Gerald M, Berman, Brian, Panepinto, Julie A, Fuh, Beng R, Kwiatkowski, Janet L, King, Allison A, Fixler, Jason M, Rhodes, Melissa M, Thompson, Alexis A, Heiny, Mark E, Redding-Lallinger, Rupa C, Kirkham, Fenella J, Dixon, Natalia, Gonzalez, Corina E, Kalinyak, Karen A, Quinn, Charles T, Strouse, John J, Miller, J. Philip, Lehmann, Harold, Kraut, Michael A, Ball, William S, Hirtz, Deborah, Casella, James F
Published in The New England journal of medicine (21.08.2014)
Published in The New England journal of medicine (21.08.2014)
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Journal Article
State-dependent alterations in sleep/wake architecture elicited by the M4 PAM VU0467154 – Relation to antipsychotic-like drug effects
Gould, Robert W., Nedelcovych, Michael T., Gong, Xuewen, Tsai, Erica, Bubser, Michael, Bridges, Thomas M., Wood, Michael R., Duggan, Mark E., Brandon, Nicholas J., Dunlop, John, Wood, Michael W., Ivarsson, Magnus, Noetzel, Meredith J., Daniels, J. Scott, Niswender, Colleen M., Lindsley, Craig W., Conn, P. Jeffrey, Jones, Carrie K.
Published in Neuropharmacology (01.03.2016)
Published in Neuropharmacology (01.03.2016)
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Journal Article
Discovery of VU0467485/AZ13713945: An M4 PAM Evaluated as a Preclinical Candidate for the Treatment of Schizophrenia
Wood, Michael R., Noetzel, Meredith J., Melancon, Bruce J., Poslusney, Michael S., Nance, Kellie D., Hurtado, Miguel A., Luscombe, Vincent B., Weiner, Rebecca L., Rodriguez, Alice L., Lamsal, Atin, Chang, Sichen, Bubser, Michael, Blobaum, Anna L., Engers, Darren W., Niswender, Colleen M., Jones, Carrie K., Brandon, Nicholas J., Wood, Michael W., Duggan, Mark E., Conn, P. Jeffrey, Bridges, Thomas M., Lindsley, Craig W.
Published in ACS medicinal chemistry letters (09.02.2017)
Published in ACS medicinal chemistry letters (09.02.2017)
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Journal Article
Pediatric Hemorrhagic Brainstem Encephalitis Associated With HHV-7 Infection
Fay, Alex J., MD, PhD, Noetzel, Michael J., MD, Mar, Soe S., MD
Published in Pediatric neurology (01.12.2015)
Published in Pediatric neurology (01.12.2015)
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Journal Article
Headache and Migraine in Children with Sickle Cell Disease Are Associated with Lower Hemoglobin and Higher Pain Event Rates But Not Silent Cerebral Infarction
Dowling, Michael M., MD, PhD, MSCS, Noetzel, Michael J., MD, Rodeghier, Mark J., PhD, Quinn, Charles T., MD, MS, Hirtz, Deborah G., MD, Ichord, Rebecca N., MD, Kwiatkowski, Janet L., MD, MSCE, Roach, E. Steven, MD, Kirkham, Fenella J., MD, FRCPCH, Casella, James F., MD, DeBaun, Michael R., MD, MPH
Published in The Journal of pediatrics (01.05.2014)
Published in The Journal of pediatrics (01.05.2014)
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Cost Analysis for Patients Hospitalised for Heart Failure in Germany
Baierlein, J, Hacker, J, Brachmann, J, Grewe, P.H, Noetzel, J, Lecomte, P, Neidhardt, K
Published in Value in health (01.11.2013)
Published in Value in health (01.11.2013)
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Journal Article
Predicting Recovery and Outcome after Pediatric Stroke: Results from the International Pediatric Stroke Study
Felling, Ryan J., Rafay, Mubeen F., Bernard, Timothy J., Carpenter, Jessica L., Dlamini, Nomazulu, Hassanein, Sahar M. A., Jordan, Lori C., Noetzel, Michael J., Rivkin, Michael J., Shapiro, Kevin A., Slim, Mahmoud, deVeber, Gabrielle
Published in Annals of neurology (01.06.2020)
Published in Annals of neurology (01.06.2020)
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Pediatric Ischemic Stroke: An Infrequent Complication of SARS‐CoV‐2
Beslow, Lauren A., Linds, Alexandra B., Fox, Christine K., Kossorotoff, Manoëlle, Zuñiga Zambrano, Yenny C., Hernández‐Chávez, Marta, Hassanein, Sahar M. A., Byrne, Susan, Lim, Ming, Maduaka, Nkechi, Zafeiriou, Dimitrios, Dowling, Michael M., Felling, Ryan J., Rafay, Mubeen F., Lehman, Laura L., Noetzel, Michael J., Bernard, Timothy J., Dlamini, Nomazulu
Published in Annals of Neurology (01.04.2021)
Published in Annals of Neurology (01.04.2021)
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Selective actions of novel allosteric modulators reveal functional heteromers of metabotropic glutamate receptors in the CNS
Yin, Shen, Noetzel, Meredith J, Johnson, Kari A, Zamorano, Rocio, Jalan-Sakrikar, Nidhi, Gregory, Karen J, Conn, P Jeffrey, Niswender, Colleen M
Published in The Journal of neuroscience (01.01.2014)
Published in The Journal of neuroscience (01.01.2014)
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Journal Article
Discovery and optimization of a novel series of highly CNS penetrant M-4 PAMs based on a 5,6-dimethyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine core
Wood, Michael R., Noetzel, Meredith J., Engers, Julie L., Bollinger, Katrina A., Melancon, Bruce J., Tarr, James C., Han, Changho, West, Mary, Gregro, Alison R., Lamsal, Atin, Chang, Sichen, Ajmera, Sonia, Smith, Emery, Chase, Peter, Hodder, Peter S., Bubser, Michael, Jones, Carrie K., Hopkins, Corey R., Emmitte, Kyle A., Niswender, Colleen M., Woodf, Michael W., Duggan, Mark E., Conn, P. Jeffrey, Bridges, Thomas M., Lindsley, Craig W.
Published in Bioorganic & medicinal chemistry letters (01.07.2016)
Published in Bioorganic & medicinal chemistry letters (01.07.2016)
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Journal Article
Parent education and biologic factors influence on cognition in sickle cell anemia
King, Allison A., Strouse, John J., Rodeghier, Mark J., Compas, Bruce E., Casella, James F., McKinstry, Robert C., Noetzel, Michael J., Quinn, Charles T., Ichord, Rebecca, Dowling, Michael M., Miller, J. Philip, DeBaun, Michael R.
Published in American journal of hematology (01.02.2014)
Published in American journal of hematology (01.02.2014)
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Journal Article
Novel allosteric agonists of M1 muscarinic acetylcholine receptors induce brain region-specific responses that correspond with behavioral effects in animal models
Digby, Gregory J, Noetzel, Meredith J, Bubser, Michael, Utley, Thomas J, Walker, Adam G, Byun, Nellie E, Lebois, Evan P, Xiang, Zixiu, Sheffler, Douglas J, Cho, Hyekyung P, Davis, Albert A, Nemirovsky, Natali E, Mennenga, Sarah E, Camp, Bryan W, Bimonte-Nelson, Heather A, Bode, Jacob, Italiano, Kimberly, Morrison, Ryan, Daniels, J Scott, Niswender, Colleen M, Olive, M Foster, Lindsley, Craig W, Jones, Carrie K, Conn, P Jeffrey
Published in The Journal of neuroscience (20.06.2012)
Published in The Journal of neuroscience (20.06.2012)
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Stroke Mimics Are Not Benign in Immunocompromised Children
Mahdi, Jasia, Bach, Alicia, Smith, Alyssa E., Tomko, Stuart R., Fields, Melanie E., Griffith, Jennifer L., Morris, Stephanie M., Guerriero, Réjean M., Noetzel, Michael J., Guilliams, Kristin P., Agner, Shannon C.
Published in Stroke (1970) (01.10.2022)
Published in Stroke (1970) (01.10.2022)
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Reversible posterior leukoencephalopathy syndrome and silent cerebral infarcts are associated with severe acute chest syndrome in children with sickle cell disease
Henderson, Jessica N., Noetzel, Michael J., McKinstry, Robert C., White, Desiree A., Armstrong, Melissa, DeBaun, Michael R.
Published in Blood (15.01.2003)
Published in Blood (15.01.2003)
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Journal Article
Potentiation of M1 Muscarinic Receptor Reverses Plasticity Deficits and Negative and Cognitive Symptoms in a Schizophrenia Mouse Model
Ghoshal, A, Rook, J M, Dickerson, J W, Roop, G N, Morrison, R D, Jalan-Sakrikar, N, Lamsal, A, Noetzel, M J, Poslusney, M S, Wood, M R, Melancon, B J, Stauffer, S R, Xiang, Z, Daniels, J S, Niswender, C M, Jones, C K, Lindsley, C W, Conn, P J
Published in Neuropsychopharmacology (New York, N.Y.) (01.01.2016)
Published in Neuropsychopharmacology (New York, N.Y.) (01.01.2016)
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Prospective study of recovery following neonatal brachial plexus injury
Noetzel, M J, Park, T S, Robinson, S, Kaufman, B
Published in Journal of child neurology (01.07.2001)
Published in Journal of child neurology (01.07.2001)
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