A high‐affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain
Christensen, Nikolaj R, De Luca, Marta, Lever, Michael B, Richner, Mette, Hansen, Astrid B, Noes‐Holt, Gith, Jensen, Kathrine L, Rathje, Mette, Jensen, Dennis Bo, Erlendsson, Simon, Bartling, Christian RO, Ammendrup‐Johnsen, Ina, Pedersen, Sofie E, Schönauer, Michèle, Nissen, Klaus B, Midtgaard, Søren R, Teilum, Kaare, Arleth, Lise, Sørensen, Andreas T, Bach, Anders, Strømgaard, Kristian, Meehan, Claire F, Vægter, Christian B, Gether, Ulrik, Madsen, Kenneth L
Published in EMBO molecular medicine (08.06.2020)
Published in EMBO molecular medicine (08.06.2020)
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Journal Article
A Novel Peripheral Action of PICK1 Inhibition in Inflammatory Pain
Jensen, Kathrine Louise, Noes-Holt, Gith, Sørensen, Andreas Toft, Madsen, Kenneth Lindegaard
Published in Frontiers in cellular neuroscience (15.12.2021)
Published in Frontiers in cellular neuroscience (15.12.2021)
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Journal Article
Coding variants identified in patients with diabetes alter PICK1 BAR domain function in insulin granule biogenesis
Andersen, Rita C, Schmidt, Jan H, Rombach, Joscha, Lycas, Matthew D, Christensen, Nikolaj R, Lund, Viktor K, Stapleton, Donnie S, Pedersen, Signe S, Olsen, Mathias A, Stoklund, Mikkel, Noes-Holt, Gith, Nielsen, Tommas Te, Keller, Mark P, Jansen, Anna M, Herlo, Rasmus, Pietropaolo, Massimo, Simonsen, Jens B, Kjærulff, Ole, Holst, Birgitte, Attie, Alan D, Gether, Ulrik, Madsen, Kenneth L
Published in The Journal of clinical investigation (01.03.2022)
Published in The Journal of clinical investigation (01.03.2022)
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Journal Article
STABILIZATION OF V1 INTERNEURON-MOTOR NEURON SYNAPSES AMELIORATES MOTOR DEFICITS IN A MOUSE MODEL OF ALS
Mora, Santiago, Stuckert, Anna, Von Huth-Friis, Rasmus, Pietersz, Kimberly, Noes-Holt, Gith, Montañana-Rosell, Roser, Sørensen, Andreas Toft, Verhaagen, Joost, Selvan, Raghavendra, Allodi, Ilary
Published in IBRO neuroscience reports (01.10.2023)
Published in IBRO neuroscience reports (01.10.2023)
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Journal Article
A high‐affinity, bivalent PDZ domain inhibitor complexes PICK 1 to alleviate neuropathic pain
Christensen, Nikolaj R, De Luca, Marta, Lever, Michael B, Richner, Mette, Hansen, Astrid B, Noes‐Holt, Gith, Jensen, Kathrine L, Rathje, Mette, Jensen, Dennis Bo, Erlendsson, Simon, Bartling, Christian RO, Ammendrup‐Johnsen, Ina, Pedersen, Sofie E, Schönauer, Michèle, Nissen, Klaus B, Midtgaard, Søren R, Teilum, Kaare, Arleth, Lise, Sørensen, Andreas T, Bach, Anders, Strømgaard, Kristian, Meehan, Claire F, Vægter, Christian B, Gether, Ulrik, Madsen, Kenneth L
Published in EMBO molecular medicine (08.06.2020)
Published in EMBO molecular medicine (08.06.2020)
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Journal Article
Systematic review and meta-analysis of cannabinoids, cannabis-based medicines, and endocannabinoid system modulators tested for antinociceptive effects in animal models of injury-related or pathological persistent pain
Soliman, Nadia, Haroutounian, Simon, Hohmann, Andrea G, Krane, Elliot, Liao, Jing, Macleod, Malcolm, Segelcke, Daniel, Sena, Christopher, Thomas, James, Vollert, Jan, Wever, Kimberley, Alaverdyan, Harutyun, Barakat, Ahmed, Barthlow, Tyler, Bozer, Amber L Harris, Davidson, Alexander, Diaz-delCastillo, Marta, Dolgorukova, Antonina, Ferdousi, Mehnaz I, Healy, Catherine, Hong, Simon, Hopkins, Mary, James, Arul, Leake, Hayley B, Malewicz, Nathalie M, Mansfield, Michael, Mardon, Amelia K, Mattimoe, Darragh, McLoone, Daniel P, Noes-Holt, Gith, Pogatzki-Zahn, Esther M, Power, Emer, Pradier, Bruno, Romanos-Sirakis, Eleny, Segelcke, Astra, Vinagre, Rafael, Yanes, Julio A, Zhang, Jingwen, Zhang, Xue Ying, Finn, David P, Rice, Andrew S C
Published in Pain (Amsterdam) (01.07.2021)
Published in Pain (Amsterdam) (01.07.2021)
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Journal Article
Coding variants identified in patients with diabetes alter PICK1 BAR domain function in insulin granule biogenesis
Andersen, Rita C, Schmidt, Jan H, Rombach, Joscha, Lycas, Matthew D, Christensen, Nikolaj R, Lund, Viktor K, Stapleton, Donnie S, Pedersen, Signe S, Olsen, Mathias A, Stoklund, Mikkel, Noes-Holt, Gith, Nielsen, Tommas T E, Keller, Mark P, Jansen, Anna M, Herlo, Rasmus, Pietropaolo, Massimo, Simonsen, Jens B, Kjærulff, Ole, Holst, Birgitte, Attie, Alan D, Gether, Ulrik, Madsen, Kenneth L
Published in The Journal of clinical investigation (01.03.2022)
Published in The Journal of clinical investigation (01.03.2022)
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Journal Article
Peripherally restricted PICK1 inhibitor mPD5 ameliorates pain behaviors in murine inflammatory and neuropathic pain models
Jensen, Kathrine Louise, Christensen, Nikolaj Riis, Goddard, Carolyn Marie, Jager, Sara Elgaard, Noes-Holt, Gith, Kanneworff, Ida Buur, Jakobsen, Alexander, Jiménez-Fernández, Lucía, Peck, Emily G, Sivertsen, Line, Comaposada-Baro, Raquel, Houser, Grace Anne, Mayer, Felix Paul, Diaz-delCastillo, Marta, Topp, Marie Løth, Hopkins, Chelsea, Thomsen, Cecilie Dubgaard, Ibrahim Soltan, Ahmed Barakat, Tidenmand, Federik Grønbæk, Arleth, Lise, Heegaard, Anne-Marie, Sørensen, Andreas Toft, Madsen, Kenneth Lindegaard
Published in JCI insight (17.09.2024)
Published in JCI insight (17.09.2024)
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Journal Article
Recombinant dimeric PDZ protein inhibitors for long-term relief of chronic pain by AAV therapeutics
Noes-Holt, Gith, Jensen, Kathrine Louise, Richner, Mette, Baro, Raquel Comaposada, Sivertsen, Line, Jager, Sara Elgaard, Lucia Jimenez Fernandez, Rita Chan Andersen, Lilja, Jamila H, Larsen, Andreas Haahr, Christiansen, Nikolaj Riis, Tappe-Theodor, Anke E, Vaegter, Christian Bjerggaard, Kuner, Rohini, Kenneth Lindegaard Madsen, Andreas Toft Soerensen
Published in bioRxiv (03.03.2023)
Published in bioRxiv (03.03.2023)
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Paper
Coding variants identified in diabetic patients alter PICK1 BAR domain function in insulin granule biogenesis
Andersen, Rita C, Lycas, Matthew D, Schmidt, Jan H, Christensen, Nikolaj R, Lund, Viktor K, Rombach, Joscha, Stoklund, Mikkel, Stapleton, Donnie S, Noes-Holt, Gith, Keller, Mark P, Jansen, Anna M, Herlo, Rasmus, Kjærulff, Ole, Holst, Birgitte, Attie, Alan D, Gether, Ulrik, Madsen, Kenneth L
Published in bioRxiv (05.10.2020)
Published in bioRxiv (05.10.2020)
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