Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease
Stockwell, Brent R., Friedmann Angeli, José Pedro, Bayir, Hülya, Bush, Ashley I., Conrad, Marcus, Dixon, Scott J., Fulda, Simone, Gascón, Sergio, Hatzios, Stavroula K., Kagan, Valerian E., Noel, Kay, Jiang, Xuejun, Linkermann, Andreas, Murphy, Maureen E., Overholtzer, Michael, Oyagi, Atsushi, Pagnussat, Gabriela C., Park, Jason, Ran, Qitao, Rosenfeld, Craig S., Salnikow, Konstantin, Tang, Daolin, Torti, Frank M., Torti, Suzy V., Toyokuni, Shinya, Woerpel, K.A., Zhang, Donna D.
Published in Cell (05.10.2017)
Published in Cell (05.10.2017)
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Journal Article
Phenylalanine blood levels and clinical outcomes in phenylketonuria: A systematic literature review and meta-analysis
Waisbren, Susan E., Noel, Kay, Fahrbach, Kyle, Cella, Catherine, Frame, Diana, Dorenbaum, Alex, Levy, Harvey
Published in Molecular genetics and metabolism (01.09.2007)
Published in Molecular genetics and metabolism (01.09.2007)
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Journal Article
Minimally Invasive Colorectal Resection Outcomes: Short-term Comparison with Open Procedures
Noel, J. Kay, PhD, Fahrbach, Kyle, PhD, Estok, Rhonda, RN, BSN, Cella, Catherine, BA, Frame, Diana, MEM, Linz, Heather, BA, Cima, Robert R., MD, FACS, Dozois, Eric J., MD, FACS, Senagore, Anthony J., MD, FACS
Published in Journal of the American College of Surgeons (01.02.2007)
Published in Journal of the American College of Surgeons (01.02.2007)
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Journal Article
Systematic Review and Meta-Analysis of Neuropsychiatric Symptoms and Executive Functioning in Adults With Phenylketonuria
Bilder, Deborah A., Noel, J. Kay, Baker, Erin R., Irish, William, Chen, Yinpu, Merilainen, Markus J., Prasad, Suyash, Winslow, Barbara J.
Published in Developmental neuropsychology (18.05.2016)
Published in Developmental neuropsychology (18.05.2016)
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Journal Article
OTX015 (MK‐8628), a novel BET inhibitor, displays in vitro and in vivo antitumor effects alone and in combination with conventional therapies in glioblastoma models
Berenguer‐Daizé, Caroline, Astorgues‐Xerri, Lucile, Odore, Elodie, Cayol, Mylène, Cvitkovic, Esteban, Noel, Kay, Bekradda, Mohamed, MacKenzie, Sarah, Rezai, Keyvan, Lokiec, François, Riveiro, Maria E., Ouafik, L'Houcine
Published in International journal of cancer (01.11.2016)
Published in International journal of cancer (01.11.2016)
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Journal Article
OTX015 (MK-8628), a novel BET inhibitor, exhibits antitumor activity in non-small cell and small cell lung cancer models harboring different oncogenic mutations
Riveiro, Maria E, Astorgues-Xerri, Lucile, Vazquez, Ramiro, Frapolli, Roberta, Kwee, Ivo, Rinaldi, Andrea, Odore, Elodie, Rezai, Keyvan, Bekradda, Mohamed, Inghirami, Giorgio, D'Incalci, Maurizio, Noel, Kay, Cvitkovic, Esteban, Raymond, Eric, Bertoni, Francesco
Published in Oncotarget (20.12.2016)
Published in Oncotarget (20.12.2016)
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Journal Article
Abstract LB-108: A potent and selective small molecule degrader of STAT5 for the treatment of hematological malignancies
Park, Ji Sung, Tin, Gary, de Araujo, Elvin D., Orlova, Anna, Sorger, Helena, Grebien, Florian, Heyes, Elizabeth, Geletu, Mulu, Villalonga, Ruth, Sampedro, Angel, Sedighi, Abootaleb, Herling, Marco, Mustjoki, Satu, Eram, Mohammad S., Ahmar, Siawash, Moriggl, Richard, O'Meara, Jeff A., Proudfoot, John, Noel, Kay, Kraskouskaya, Dziyana, Fleck, Roman, Gunning, Patrick T.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Systematic review to establish the safety profiles for direct and indirect inhibitors of p38 Mitogen-activated protein kinases for treatment of cancer: A systematic review of the literature
Noel, J. Kay, Crean, Sheila, Claflin, Janet E., Ranganathan, Gayatri, Linz, Heather, Lahn, Michael
Published in Medical oncology (Northwood, London, England) (01.09.2008)
Published in Medical oncology (Northwood, London, England) (01.09.2008)
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Journal Article
Pharmacokinetics and antineoplastic activity of galectin-1-targeting OTX008 in combination with sunitinib
Zucchetti, Massimo, Bonezzi, Katiuscia, Frapolli, Roberta, Sala, Federica, Borsotti, Patrizia, Zangarini, Monique, Cvitkovic, Esteban, Noel, Kay, Ubezio, Paolo, Giavazzi, Raffaella, D’Incalci, Maurizio, Taraboletti, Giulia
Published in Cancer chemotherapy and pharmacology (01.10.2013)
Published in Cancer chemotherapy and pharmacology (01.10.2013)
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Journal Article
Insights into the cellular pharmacological properties of the BET-inhibitor OTX015/MK-8628 (birabresib), alone and in combination, in leukemia models
Astorgues-Xerri, Lucile, Vázquez, Ramiro, Odore, Elodie, Rezai, Keyvan, Kahatt, Carmen, Mackenzie, Sarah, Bekradda, Mohamed, Coudé, Marie-Magdelaine, Dombret, Herve, Gardin, Claude, Lokiec, Francois, Raymond, Eric, Noel, Kay, Cvitkovic, Esteban, Herait, Patrice, Bertoni, Francesco, Riveiro, María E.
Published in Leukemia & lymphoma (15.10.2019)
Published in Leukemia & lymphoma (15.10.2019)
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Journal Article
OTX015 (MK-8628), a novel BET inhibitor, displays in vitroand in vivo antitumor effects alone and in combination withconventional therapies in glioblastoma models
Berenguer-Daize, Caroline, Astorgues-Xerri, Lucile, Odore, Elodie, Cayol, Mylène, Cvitkovic, Esteban, Noel, Kay, Bekradda, Mohamed, Mackenzie, Sarah, Rezai, Keyvan, Lokiec, François, Riveiro, Maria E., Ouafik, L’houcine
Published in International journal of cancer (2016)
Published in International journal of cancer (2016)
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Journal Article
Abstract A121: Preclinical evaluation of OTX015 a novel BET-BRD inhibitor across a panel of solid tumor cell lines of different lineages
Riveiro, Maria Eugenia, Astorgues-Xerri, Lucile, Odore, Elodie, Bekradda, Mohamed, Cvitkovic, Esteban, Noel, Kay, Raymond, Eric
Published in Molecular cancer therapeutics (01.11.2013)
Published in Molecular cancer therapeutics (01.11.2013)
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Journal Article
Abstract A194: OTX008, a small molecule that inhibits galectin-1, potentiates the in vitro effects of cytotoxic and targeted agents in several human cancer models
Astorgues-xerri, Lucile, Riveiro, Maria Eugenia, Noel, Kay, Cvitkovic, Esteban, Bekradda, Mohamed, Serova, Maria, Faivre, Sandrine, Raymond, Eric
Published in Molecular cancer therapeutics (01.11.2013)
Published in Molecular cancer therapeutics (01.11.2013)
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Journal Article
The Brd-Inhibitor OTX015 Is Active in Pre-Clinical Models of Mature B-Cell Lymphoid Tumors
Bonetti, Paola, Boi, Michela, Ponzoni, Maurilio, Tibiletti, Maria Grazia, Stahis, Anastasios, Inghirami, Giorgio, Noel, Kay, Zucca, Emanuele, Bertoni, Francesco
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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Journal Article
Genetic Factors Predicting The Response To BET Bromodomain Inhibitors In Lymphoma Lead To New Synergistic Combinations
Gaudio, Eugenio, Kwee, Ivo, Rinaldi, Andrea, Boi, Michela, Bernasconi, Elena, Testoni, Monica, Stathis, Anastasios, Herait, Patrice, Noel, Kay, Inghirami, Giorgio, Zucca, Emanuele, Bertoni, Francesco
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Journal Article
Abstract A119: The BET-bromodomain inhibitor OTX015 shows synergism with several anticancer agents in preclinical models of diffuse large B-cell lymphoma (DLBCL)
Gaudio, Eugenio, Kwee, Ivo, Bernasconi, Elena, Rinaldi, Andrea, Testoni, Monica, Boi, Michela, Stathis, Anastasios, Riveiro, Eugenia, Noel, Kay, Zucca, Emanuele, Bertoni, Francesco
Published in Molecular cancer therapeutics (01.11.2013)
Published in Molecular cancer therapeutics (01.11.2013)
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Journal Article
Abstract 681: PTX-008, a novel galectin-1 targeting agent, improves the effects of cytotoxic drugs in colon cancer cells
Astorgues-Xerri, Lucile, Serova, Maria, Riveiro, Maria E., Cvitkovic, Esteban, Noel, Kay, Raymond, Eric, Faivre, Sandrine
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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