Obesity-associated variants within FTO form long-range functional connections with IRX3
Smemo, Scott, Tena, Juan J., Kim, Kyoung-Han, Gamazon, Eric R., Sakabe, Noboru J., Gómez-Marín, Carlos, Aneas, Ivy, Credidio, Flavia L., Sobreira, Débora R., Wasserman, Nora F., Lee, Ju Hee, Puviindran, Vijitha, Tam, Davis, Shen, Michael, Son, Joe Eun, Vakili, Niki Alizadeh, Sung, Hoon-Ki, Naranjo, Silvia, Acemel, Rafael D., Manzanares, Miguel, Nagy, Andras, Cox, Nancy J., Hui, Chi-Chung, Gomez-Skarmeta, Jose Luis, Nóbrega, Marcelo A.
Published in Nature (London) (20.03.2014)
Published in Nature (London) (20.03.2014)
Get full text
Journal Article
Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5
Sobreira, Débora R., Joslin, Amelia C., Zhang, Qi, Williamson, Iain, Hansen, Grace T., Farris, Kathryn M., Sakabe, Noboru J., Sinnott-Armstrong, Nasa, Bozek, Grazyna, Jensen-Cody, Sharon O., Flippo, Kyle H., Ober, Carole, Bickmore, Wendy A., Potthoff, Matthew, Chen, Mengjie, Claussnitzer, Melina, Aneas, Ivy, Nóbrega, Marcelo A.
Published in Science (American Association for the Advancement of Science) (04.06.2021)
Published in Science (American Association for the Advancement of Science) (04.06.2021)
Get full text
Journal Article
A promoter interaction map for cardiovascular disease genetics
Montefiori, Lindsey E, Sobreira, Debora R, Sakabe, Noboru J, Aneas, Ivy, Joslin, Amelia C, Hansen, Grace T, Bozek, Grazyna, Moskowitz, Ivan P, McNally, Elizabeth M, Nóbrega, Marcelo A
Published in eLife (10.07.2018)
Published in eLife (10.07.2018)
Get full text
Journal Article
A functional genomics pipeline identifies pleiotropy and cross-tissue effects within obesity-associated GWAS loci
Joslin, Amelia C., Sobreira, Débora R., Hansen, Grace T., Sakabe, Noboru J., Aneas, Ivy, Montefiori, Lindsey E., Farris, Kathryn M., Gu, Jing, Lehman, Donna M., Ober, Carole, He, Xin, Nóbrega, Marcelo A.
Published in Nature communications (06.09.2021)
Published in Nature communications (06.09.2021)
Get full text
Journal Article
Genetic Variation in Enhancers Modifies Cardiomyopathy Gene Expression and Progression
Gacita, Anthony M., Fullenkamp, Dominic E., Ohiri, Joyce, Pottinger, Tess, Puckelwartz, Megan J., Nobrega, Marcelo A., McNally, Elizabeth M.
Published in Circulation (New York, N.Y.) (30.03.2021)
Published in Circulation (New York, N.Y.) (30.03.2021)
Get full text
Journal Article
Evolutionary comparison reveals that diverging CTCF sites are signatures of ancestral topological associating domains borders
Gómez-Marín, Carlos, Tena, Juan J, Acemel, Rafael D, López-Mayorga, Macarena, Naranjo, Silvia, de la Calle-Mustienes, Elisa, Maeso, Ignacio, Beccari, Leonardo, Aneas, Ivy, Vielmas, Erika, Bovolenta, Paola, Nobrega, Marcelo A, Carvajal, Jaime, Gómez-Skarmeta, José Luis
Published in Proceedings of the National Academy of Sciences - PNAS (16.06.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (16.06.2015)
Get full text
Journal Article
HIF1α Represses Cell Stress Pathways to Allow Proliferation of Hypoxic Fetal Cardiomyocytes
Guimarães-Camboa, Nuno, Stowe, Jennifer, Aneas, Ivy, Sakabe, Noboru, Cattaneo, Paola, Henderson, Lindsay, Kilberg, Michael S., Johnson, Randall S., Chen, Ju, McCulloch, Andrew D., Nobrega, Marcelo A., Evans, Sylvia M., Zambon, Alexander C.
Published in Developmental cell (08.06.2015)
Published in Developmental cell (08.06.2015)
Get full text
Journal Article
Pluripotent stem cell-derived endometrial stromal fibroblasts in a cyclic, hormone-responsive, coculture model of human decidua
Cheung, Virginia Chu, Peng, Chian-Yu, Marinić, Mirna, Sakabe, Noboru J., Aneas, Ivy, Lynch, Vincent J., Ober, Carole, Nobrega, Marcelo A., Kessler, John A.
Published in Cell reports (Cambridge) (18.05.2021)
Published in Cell reports (Cambridge) (18.05.2021)
Get full text
Journal Article
Targeted Germline Modifications in Rats Using CRISPR/Cas9 and Spermatogonial Stem Cells
Chapman, Karen M., Medrano, Gerardo A., Jaichander, Priscilla, Chaudhary, Jaideep, Waits, Alexandra E., Nobrega, Marcelo A., Hotaling, James M., Ober, Carole, Hamra, F. Kent
Published in Cell reports (Cambridge) (24.03.2015)
Published in Cell reports (Cambridge) (24.03.2015)
Get full text
Journal Article
Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism
Savic, Daniel, Ye, Honggang, Aneas, Ivy, Park, Soo-Young, Bell, Graeme I, Nobrega, Marcelo A
Published in Genome research (01.09.2011)
Published in Genome research (01.09.2011)
Get full text
Journal Article
Genetics of sexually dimorphic adipose distribution in humans
Hansen, Grace T., Sobreira, Débora R., Weber, Zachary T., Thornburg, Alexis G., Aneas, Ivy, Zhang, Li, Sakabe, Noboru J., Joslin, Amelia C., Haddad, Gabriela A., Strobel, Sophie M., Laber, Samantha, Sultana, Farhath, Sahebdel, Faezeh, Khan, Kohinoor, Li, Yang I., Claussnitzer, Melina, Ye, Liang, Battaglino, Ricardo A., Nóbrega, Marcelo A.
Published in Nature genetics (01.03.2023)
Published in Nature genetics (01.03.2023)
Get full text
Journal Article
A Fine-Scale Chimpanzee Genetic Map from Population Sequencing
Auton, Adam, Fledel-Alon, Adi, Pfeifer, Susanne, Venn, Oliver, Ségurel, Laure, Street, Teresa, Leffler, Ellen M., Bowden, Rory, Aneas, Ivy, Broxholme, John, Humburg, Peter, Iqbal, Zamin, Lunter, Gerton, Maller, Julian, Hernandez, Ryan D., Melton, Cord, Venkat, Aarti, Nobrega, Marcelo A., Bontrop, Ronald, Myers, Simon, Donnelly, Peter, Przeworski, Molly, McVean, Gil
Published in Science (American Association for the Advancement of Science) (13.04.2012)
Published in Science (American Association for the Advancement of Science) (13.04.2012)
Get full text
Journal Article
Identification of atrial fibrillation associated genes and functional non-coding variants
van Ouwerkerk, Antoinette F., Bosada, Fernanda M., van Duijvenboden, Karel, Hill, Matthew C., Montefiori, Lindsey E., Scholman, Koen T., Liu, Jia, de Vries, Antoine A. F., Boukens, Bastiaan J., Ellinor, Patrick T., Goumans, Marie José T. H., Efimov, Igor R., Nobrega, Marcelo A., Barnett, Phil, Martin, James F., Christoffels, Vincent M.
Published in Nature communications (18.10.2019)
Published in Nature communications (18.10.2019)
Get full text
Journal Article
A common genetic variant within SCN10A modulates cardiac SCN5A expression
van den Boogaard, Malou, Smemo, Scott, Burnicka-Turek, Ozanna, Arnolds, David E, van de Werken, Harmen J G, Klous, Petra, McKean, David, Muehlschlegel, Jochen D, Moosmann, Julia, Toka, Okan, Yang, Xinan H, Koopmann, Tamara T, Adriaens, Michiel E, Bezzina, Connie R, de Laat, Wouter, Seidman, Christine, Seidman, J G, Christoffels, Vincent M, Nobrega, Marcelo A, Barnett, Phil, Moskowitz, Ivan P
Published in The Journal of clinical investigation (01.04.2014)
Published in The Journal of clinical investigation (01.04.2014)
Get full text
Journal Article
Comparative genomics at the vertebrate extremes
Rubin, Edward M, Boffelli, Dario, Nobrega, Marcelo A
Published in Nature reviews. Genetics (01.06.2004)
Published in Nature reviews. Genetics (01.06.2004)
Get full text
Journal Article
Single cell profiling at the maternal–fetal interface reveals a deficiency of PD-L1+ non-immune cells in human spontaneous preterm labor
Liu, Xiao, Aneas, Ivy, Sakabe, Noboru, Anderson, Rebecca L., Billstrand, Christine, Paz, Cristina, Kaur, Harjot, Furner, Brian, Choi, Seong, Prichina, Adriana Y., Enninga, Elizabeth Ann L., Dong, Haidong, Murtha, Amy, Crawford, Gregory E., Kessler, John A., Grobman, William, Nobrega, Marcelo A., Rana, Sarosh, Ober, Carole
Published in Scientific reports (16.05.2023)
Published in Scientific reports (16.05.2023)
Get full text
Journal Article
Probing chromatin landscape reveals roles of endocardial TBX20 in septation
Boogerd, Cornelis J, Aneas, Ivy, Sakabe, Noboru, Dirschinger, Ralph J, Cheng, Quen J, Zhou, Bin, Chen, Ju, Nobrega, Marcelo A, Evans, Sylvia M
Published in The Journal of clinical investigation (01.08.2016)
Published in The Journal of clinical investigation (01.08.2016)
Get full text
Journal Article