325 Identification and characterization of an irreversible inhibitor of CDK2
Martin, M, Anscombe, E, Meschini, E, Staunton, D, Geitmann, M, Danielson, U.H, Wang, L.Z, Vidal, R. Mora, Reuillon, T, Golding, B.T, Newell, D.R, Wedge, S, Noble, M.E.M, Endicott, J.A, Griffin, R.J
Published in European journal of cancer (1990) (01.11.2014)
Published in European journal of cancer (1990) (01.11.2014)
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276 An X-ray crystal structure-based understanding of the inhibition of the MDM2–p53 protein–protein interaction by isoindolinones
Anil, B, Blackburn, E, Blackburn, T, Cully, S, Liu, J, Drummond, C.J, Endicott, J.A, Golding, B.T, Griffin, R.J, Haggerty, K, Lunec, J, Newell, D.R, Revill, C.H, Riedinger, C, Watson, A.F, Xu, Q, Zhao, Y, Hardcastle, I.R, Noble, M.E.M
Published in European journal of cancer (1990) (01.11.2014)
Published in European journal of cancer (1990) (01.11.2014)
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445 Structure-based design of C8-substituted O6-alkylguanine CDK1 and 2 inhibitors
Carbain, B, Roche, C, Endicott, J.A, Golding, B.T, Hardcastle, I.R, Cano, C, Zhen-Wang, L, Newell, D.R, Noble, M.E.M, Griffin, R.J
Published in European journal of cancer supplements (2010)
Published in European journal of cancer supplements (2010)
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structure of CDK4/cyclin D3 has implications for models of CDK activation
Takaki, T, Echalier, A, Brown, N.R, Hunt, T, Endicott, J.A, Noble, M.E.M
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2009)
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The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition
Lowe, E.D., Noble, M.E.M., Skamnaki, V.T., Oikonomakos, N.G., Owen, D.J., Johnson, L.N.
Published in The EMBO journal (17.11.1997)
Published in The EMBO journal (17.11.1997)
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Refined 1.83 Å structure of trypanosomal triosephosphate isomerase crystallized in the presence of 2.4 m-ammonium sulphate : A comparison with the structure of the trypanosomal triosephosphate isomerase-glycerol-3-phosphate complex
Wierenga, R.K., Noble, M.E.M., Vriend, G., Nauche, S., Hol, W.G.J.
Published in Journal of molecular biology (20.08.1991)
Published in Journal of molecular biology (20.08.1991)
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Expression, Purification and Crystallisation of Phosphorylase Kinase Catalytic Domain
Owen, D.J., Papageorgiou, A.C., Garman, E.F., Noble, M.E.M., Johnson, L.N.
Published in Journal of molecular biology (24.02.1995)
Published in Journal of molecular biology (24.02.1995)
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Anion binding at the active site of trypanosomal triosephosphate isomerase: monohydrogen phosphate does not mimic sulphate
Verlinde, C.L.M.J. (University of Groningen, Groningen, The Netherlands), Noble, M.E.M, Kalk, K.H, Groendijk, H, Wierenga, R.K, Hol, W.G.J
Published in European journal of biochemistry (23.05.1991)
Published in European journal of biochemistry (23.05.1991)
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