Transcriptomic Profiling of the Tumor Microenvironment Reveals Distinct Subgroups of Clear Cell Renal Cell Cancer: Data from a Randomized Phase III Trial
Hakimi, A Ari, Voss, Martin H, Kuo, Fengshen, Sanchez, Alejandro, Liu, Ming, Nixon, Briana G, Vuong, Lynda, Ostrovnaya, Irina, Chen, Ying-Bei, Reuter, Victor, Riaz, Nadeem, Cheng, Yuan, Patel, Parul, Marker, Mahtab, Reising, Albert, Li, Ming O, Chan, Timothy A, Motzer, Robert J
Published in Cancer discovery (01.04.2019)
Published in Cancer discovery (01.04.2019)
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Cytotoxic innate lymphoid cells sense cancer cell-expressed interleukin-15 to suppress human and murine malignancies
Kansler, Emily R, Dadi, Saïda, Krishna, Chirag, Nixon, Briana G, Stamatiades, Efstathios G, Liu, Ming, Kuo, Fengshen, Zhang, Jing, Zhang, Xian, Capistrano, Kristelle, Blum, Kyle A, Weiss, Kate, Kedl, Ross M, Cui, Guangwei, Ikuta, Koichi, Chan, Timothy A, Leslie, Christina S, Hakimi, A Ari, Li, Ming O
Published in Nature immunology (01.06.2022)
Published in Nature immunology (01.06.2022)
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Cytotoxic granzyme C-expressing ILC1s contribute to antitumor immunity and neonatal autoimmunity
Nixon, Briana G, Chou, Chun, Krishna, Chirag, Dadi, Saïda, Michel, Adam O, Cornish, Andrew E, Kansler, Emily R, Do, Mytrang H, Wang, Xinxin, Capistrano, Kristelle J, Rudensky, Alexander Y, Leslie, Christina S, Li, Ming O
Published in Science immunology (08.04.2022)
Published in Science immunology (08.04.2022)
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Tumor-intrinsic PRC2 inactivation drives a context-dependent immune-desert microenvironment and is sensitized by immunogenic viruses
Yan, Juan, Chen, Yuedan, Patel, Amish J, Warda, Sarah, Lee, Cindy J, Nixon, Briana G, Wong, Elissa Wp, Miranda-Román, Miguel A, Yang, Ning, Wang, Yi, Pachai, Mohini R, Sher, Jessica, Giff, Emily, Tang, Fanying, Khurana, Ekta, Singer, Sam, Liu, Yang, Galbo, Jr, Phillip M, Maag, Jesper Lv, Koche, Richard P, Zheng, Deyou, Antonescu, Cristina R, Deng, Liang, Li, Ming O, Chen, Yu, Chi, Ping
Published in The Journal of clinical investigation (01.09.2022)
Published in The Journal of clinical investigation (01.09.2022)
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A Targetable Myeloid Inflammatory State Governs Disease Recurrence in Clear-Cell Renal Cell Carcinoma
Rappold, Phillip M, Vuong, Lynda, Leibold, Josef, Chakiryan, Nicholas H, Curry, Michael, Kuo, Fengshen, Sabio, Erich, Jiang, Hui, Nixon, Briana G, Liu, Ming, Berglund, Anders E, Silagy, Andrew W, Mascareno, Eduardo A, Golkaram, Mahdi, Marker, Mahtab, Reising, Albert, Savchenko, Alexander, Millholland, John, Chen, Ying-Bei, Russo, Paul, Coleman, Jonathan, Reznik, Ed, Manley, Brandon J, Ostrovnaya, Irina, Makarov, Vladimir, DiNatale, Renzo G, Blum, Kyle A, Ma, Xiaoxiao, Chowell, Diego, Li, Ming O, Solit, David B, Lowe, Scott W, Chan, Timothy A, Motzer, Robert J, Voss, Martin H, Hakimi, A Ari
Published in Cancer discovery (05.10.2022)
Published in Cancer discovery (05.10.2022)
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IRF4-Dependent and IRF4-Independent Pathways Contribute to DC Dysfunction in Lupus
Manni, Michela, Gupta, Sanjay, Nixon, Briana G, Weaver, Casey T, Jessberger, Rolf, Pernis, Alessandra B
Published in PloS one (06.11.2015)
Published in PloS one (06.11.2015)
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Journal Article
TGFβ control of immune responses in cancer: a holistic immuno-oncology perspective
Nixon, Briana G, Gao, Shengyu, Wang, Xinxin, Li, Ming O
Published in Nature reviews. Immunology (01.06.2023)
Published in Nature reviews. Immunology (01.06.2023)
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Cancer immunotherapy via targeted TGF-β signalling blockade in TH cells
Li, Shun, Liu, Ming, Do, Mytrang H., Chou, Chun, Stamatiades, Efstathios G., Nixon, Briana G., Shi, Wei, Zhang, Xian, Li, Peng, Gao, Shengyu, Capistrano, Kristelle J., Xu, Hong, Cheung, Nai-Kong V., Li, Ming O.
Published in Nature (London) (05.11.2020)
Published in Nature (London) (05.11.2020)
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TGF-β suppresses type 2 immunity to cancer
Liu, Ming, Kuo, Fengshen, Capistrano, Kristelle J, Kang, Davina, Nixon, Briana G, Shi, Wei, Chou, Chun, Do, Mytrang H, Stamatiades, Efstathios G, Gao, Shengyu, Li, Shun, Chen, Yingbei, Hsieh, James J, Hakimi, A Ari, Taniuchi, Ichiro, Chan, Timothy A, Li, Ming O
Published in Nature (London) (05.11.2020)
Published in Nature (London) (05.11.2020)
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Single-cell sequencing links multiregional immune landscapes and tissue-resident T cells in ccRCC to tumor topology and therapy efficacy
Krishna, Chirag, DiNatale, Renzo G., Kuo, Fengshen, Srivastava, Raghvendra M., Vuong, Lynda, Chowell, Diego, Gupta, Sounak, Vanderbilt, Chad, Purohit, Tanaya A., Liu, Ming, Kansler, Emily, Nixon, Briana G., Chen, Ying-Bei, Makarov, Vladimir, Blum, Kyle A., Attalla, Kyrollis, Weng, Stanley, Salmans, Michael L., Golkaram, Mahdi, Liu, Li, Zhang, Shile, Vijayaraghavan, Raakhee, Pawlowski, Traci, Reuter, Victor, Carlo, Maria I., Voss, Martin H., Coleman, Jonathan, Russo, Paul, Motzer, Robert J., Li, Ming O., Leslie, Christina S., Chan, Timothy A., Hakimi, A. Ari
Published in Cancer cell (10.05.2021)
Published in Cancer cell (10.05.2021)
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Tumor-associated macrophages expressing the transcription factor IRF8 promote T cell exhaustion in cancer
Nixon, Briana G., Kuo, Fengshen, Ji, LiangLiang, Liu, Ming, Capistrano, Kristelle, Do, Mytrang, Franklin, Ruth A., Wu, Xiaodi, Kansler, Emily R., Srivastava, Raghvendra M., Purohit, Tanaya A., Sanchez, Alejandro, Vuong, Lynda, Krishna, Chirag, Wang, Xinxin, Morse III, Herbert C., Hsieh, James J., Chan, Timothy A., Murphy, Kenneth M., Moon, James J., Hakimi, A. Ari, Li, Ming O.
Published in Immunity (Cambridge, Mass.) (08.11.2022)
Published in Immunity (Cambridge, Mass.) (08.11.2022)
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Reprogramming tumour-associated macrophages to outcompete cancer cells
Zhang, Xian, Li, Shun, Malik, Isha, Do, Mytrang H, Ji, Liangliang, Chou, Chun, Shi, Wei, Capistrano, Kristelle J, Zhang, Jing, Hsu, Ting-Wei, Nixon, Briana G, Xu, Ke, Wang, Xinxin, Ballabio, Andrea, Schmidt, Laura S, Linehan, W Marston, Li, Ming O
Published in Nature (London) (20.07.2023)
Published in Nature (London) (20.07.2023)
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Journal Article
Programme of self-reactive innate-like T cell-mediated cancer immunity
Chou, Chun, Zhang, Xian, Krishna, Chirag, Nixon, Briana G, Dadi, Saida, Capistrano, Kristelle J, Kansler, Emily R, Steele, Miranda, Han, Jian, Shyu, Amy, Zhang, Jing, Stamatiades, Efstathios G, Liu, Ming, Li, Shun, Do, Mytrang H, Edwards, Chaucie, Kang, Davina S, Chen, Chin-Tung, Wei, Iris H, Pappou, Emmanouil P, Weiser, Martin R, Garcia-Aguilar, J, Smith, J Joshua, Leslie, Christina S, Li, Ming O
Published in Nature (London) (05.05.2022)
Published in Nature (London) (05.05.2022)
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Journal Article
Nutrient mTORC1 signaling underpins regulatory T cell control of immune tolerance
Do, Mytrang H, Wang, Xinxin, Zhang, Xian, Chou, Chun, Nixon, Briana G, Capistrano, Kristelle J, Peng, Min, Efeyan, Alejo, Sabatini, David M, Li, Ming O
Published in The Journal of experimental medicine (06.01.2020)
Published in The Journal of experimental medicine (06.01.2020)
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Reprogramming tumor-associated macrophages to outcompete endovascular endothelial progenitor cells and suppress tumor neoangiogenesis
Do, Mytrang H., Shi, Wei, Ji, Liangliang, Ladewig, Erik, Zhang, Xian, Srivastava, Raghvendra M., Capistrano, Kristelle J., Edwards, Chaucie, Malik, Isha, Nixon, Briana G., Stamatiades, Efstathios G., Liu, Ming, Li, Shun, Li, Peng, Chou, Chun, Xu, Ke, Hsu, Ting-Wei, Wang, Xinxin, Chan, Timothy A., Leslie, Christina S., Li, Ming O.
Published in Immunity (Cambridge, Mass.) (14.11.2023)
Published in Immunity (Cambridge, Mass.) (14.11.2023)
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