Engineered ACE2 receptor traps potently neutralize SARS-CoV-2
Glasgow, Anum, Glasgow, Jeff, Limonta, Daniel, Solomon, Paige, Lui, Irene, Zhang, Yang, Nix, Matthew A., Rettko, Nicholas J., Zha, Shoshana, Yamin, Rachel, Kao, Kevin, Rosenberg, Oren S., Ravetch, Jeffrey V., Wiita, Arun P., Leung, Kevin K., Lim, Shion A., Zhou, Xin X., Hobman, Tom C., Kortemme, Tanja, Wells, James A.
Published in Proceedings of the National Academy of Sciences - PNAS (10.11.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (10.11.2020)
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The surfaceome of multiple myeloma cells suggests potential immunotherapeutic strategies and protein markers of drug resistance
Ferguson, Ian D, Patiño-Escobar, Bonell, Tuomivaara, Sami T, Lin, Yu-Hsiu T, Nix, Matthew A, Leung, Kevin K, Kasap, Corynn, Ramos, Emilio, Nieves Vasquez, Wilson, Talbot, Alexis, Hale, Martina, Naik, Akul, Kishishita, Audrey, Choudhry, Priya, Lopez-Girona, Antonia, Miao, Weili, Wong, Sandy W, Wolf, Jeffrey L, Martin, 3rd, Thomas G, Shah, Nina, Vandenberg, Scott, Prakash, Sonam, Besse, Lenka, Driessen, Christoph, Posey, Jr, Avery D, Mullins, R Dyche, Eyquem, Justin, Wells, James A, Wiita, Arun P
Published in Nature communications (15.07.2022)
Published in Nature communications (15.07.2022)
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Framework humanization optimizes potency of anti-CD72 nanobody CAR-T cells for B-cell malignancies
Temple, William C, Nix, Matthew A, Naik, Akul, Izgutdina, Adila, Huang, Benjamin J, Wicaksono, Gianina, Phojanakong, Paul, Serrano, Juan Antonio Camara, Young, Elizabeth P, Ramos, Emilio, Salangsang, Fernando, Steri, Veronica, Xirenayi, Simayijiang, Hermiston, Michelle, Logan, Aaron C, Stieglitz, Elliot, Wiita, Arun P
Published in Journal for immunotherapy of cancer (24.11.2023)
Published in Journal for immunotherapy of cancer (24.11.2023)
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Journal Article
Evaluating the efficacy of multiple myeloma cell lines as models for patient tumors via transcriptomic correlation analysis
Sarin, Vishesh, Yu, Katharine, Ferguson, Ian D, Gugliemini, Olivia, Nix, Matthew A, Hann, Byron, Sirota, Marina, Wiita, Arun P
Published in Leukemia (01.10.2020)
Published in Leukemia (01.10.2020)
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Journal Article
IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells
Lee, Jaewoong, Robinson, Mark E, Ma, Ning, Artadji, Dewan, Ahmed, Mohamed A, Xiao, Gang, Sadras, Teresa, Deb, Gauri, Winchester, Janet, Cosgun, Kadriye Nehir, Geng, Huimin, Chan, Lai N, Kume, Kohei, Miettinen, Teemu P, Zhang, Ye, Nix, Matthew A, Klemm, Lars, Chen, Chun Wei, Chen, Jianjun, Khairnar, Vishal, Wiita, Arun P, Thomas-Tikhonenko, Andrei, Farzan, Michael, Jung, Jae U, Weinstock, David M, Manalis, Scott R, Diamond, Michael S, Vaidehi, Nagarajan, Müschen, Markus
Published in Nature (London) (17.12.2020)
Published in Nature (London) (17.12.2020)
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Journal Article
Signalling input from divergent pathways subverts B cell transformation
Chan, Lai N, Murakami, Mark A, Robinson, Mark E, Caeser, Rebecca, Sadras, Teresa, Lee, Jaewoong, Cosgun, Kadriye Nehir, Kume, Kohei, Khairnar, Vishal, Xiao, Gang, Ahmed, Mohamed A, Aghania, Eamon, Deb, Gauri, Hurtz, Christian, Shojaee, Seyedmehdi, Hong, Chao, Pölönen, Petri, Nix, Matthew A, Chen, Zhengshan, Chen, Chun Wei, Chen, Jianjun, Vogt, Andreas, Heinäniemi, Merja, Lohi, Olli, Wiita, Arun P, Izraeli, Shai, Geng, Huimin, Weinstock, David M, Müschen, Markus
Published in Nature (London) (30.07.2020)
Published in Nature (London) (30.07.2020)
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Journal Article
Surface Proteomics Reveals CD72 as a Target for In Vitro -Evolved Nanobody-Based CAR-T Cells in KMT2A/MLL1 -Rearranged B-ALL
Nix, Matthew A, Mandal, Kamal, Geng, Huimin, Paranjape, Neha, Lin, Yu-Hsiu T, Rivera, Jose M, Marcoulis, Makeba, White, Kristie L, Whitman, Jeffrey D, Bapat, Sagar P, Parker, Kevin R, Ramirez, Jonathan, Deucher, Anne, Phojanokong, Paul, Steri, Veronica, Fattahi, Faranak, Hann, Byron C, Satpathy, Ansuman T, Manglik, Aashish, Stieglitz, Elliot, Wiita, Arun P
Published in Cancer discovery (01.08.2021)
Published in Cancer discovery (01.08.2021)
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Journal Article
β-Defensin Mutation Causes Black Coat Color in Domestic Dogs
Candille, Sophie I, Kaelin, Christopher B, Cattanach, Bruce M, Yu, Bin, Thompson, Darren A, Nix, Matthew A, Kerns, Julie A, Schmutz, Sheila M, Millhauser, Glenn L, Barsh, Gregory S
Published in Science (American Association for the Advancement of Science) (30.11.2007)
Published in Science (American Association for the Advancement of Science) (30.11.2007)
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Human β‐defensin 3 affects the activity of pro‐inflammatory pathways associated with MyD88 and TRIF
Semple, Fiona, MacPherson, Heather, Webb, Sheila, Cox, Sarah L., Mallin, Lucy J., Tyrrell, Christine, Grimes, Graeme R., Semple, Colin A., Nix, Matthew A., Millhauser, Glenn L., Dorin, Julia R.
Published in European journal of immunology (01.11.2011)
Published in European journal of immunology (01.11.2011)
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Journal Article
Defining MC1R Regulation in Human Melanocytes by Its Agonist α-Melanocortin and Antagonists Agouti Signaling Protein and β-Defensin 3
Swope, Viki B., Jameson, Joshua A., McFarland, Kevin L., Supp, Dorothy M., Miller, William E., McGraw, Dennis W., Patel, Mira A., Nix, Matthew A., Millhauser, Glenn L., Babcock, George F., Abdel-Malek, Zalfa A.
Published in Journal of investigative dermatology (01.09.2012)
Published in Journal of investigative dermatology (01.09.2012)
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Journal Article
Author Correction: IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells
Lee, Jaewoong, Robinson, Mark E, Ma, Ning, Artadji, Dewan, Ahmed, Mohamed A, Xiao, Gang, Sadras, Teresa, Deb, Gauri, Winchester, Janet, Cosgun, Kadriye Nehir, Geng, Huimin, Chan, Lai N, Kume, Kohei, Miettinen, Teemu P, Zhang, Ye, Nix, Matthew A, Klemm, Lars, Chen, Chun Wei, Chen, Jianjun, Khairnar, Vishal, Wiita, Arun P, Thomas-Tikhonenko, Andrei, Farzan, Michael, Jung, Jae U, Weinstock, David M, Manalis, Scott R, Diamond, Michael S, Vaidehi, Nagarajan, Müschen, Markus
Published in Nature (London) (01.04.2021)
Published in Nature (London) (01.04.2021)
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Journal Article
CD72 Nanobody-Based CAR-T Cells Have Potent Anti-Tumor Efficacy in B Cell Malignancies
Nix, Matthew A, Temple, William C, Karlon, William, Wang, Donghui, Phojanakong, Paul, Steri, Veronica, Hann, Byron, Wiita, Arun P
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Humanized Nanobody Anti-CD72 CAR-T Cells Efficiently Eliminate B-Cell Malignancies Via Improved Affinity for CD72 but Induce Persistent Antigen Downregulation In Vivo
Temple, William C, Wicaksono, Gianina, Naik, Akul, Izgutdina, Adila, Nix, Matthew A, Young, Elizabeth, Phojanakong, Paul, Serrano, Juan Antonio Camara, Steri, Veronica, Salangsang, Fernando, Wiita, Arun P
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Engineered ACE2 receptor traps potently neutralize SARS-CoV-2
Glasgow, Anum, Glasgow, Jeff, Limonta, Daniel, Solomon, Paige, Lui, Irene, Zhang, Yang, Nix, Matthew A, Rettko, Nicholas J, Lim, Shion A, Zha, Shoshana, Yamin, Rachel, Kao, Kevin, Rosenberg, Oren S, Ravetch, Jeffrey V, Wiita, Arun P, Leung, Kevin K, Zhou, Xin X, Hobman, Tom C, Kortemme, Tanja, Wells, James A
Published in bioRxiv (04.08.2020)
Published in bioRxiv (04.08.2020)
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Paper
Preclinical Development and Characterization of Humanized Anti-CD72 Nanobody Chimeric Antigen Receptor T Cells for B Cell Malignancies
Temple, William C., Izgutdina, Adila, Nix, Matthew A., Huang, Benjamin J., Phojanakong, Paul, Serrano, Juan Antonio Camara, Salangsang, Fernando, Steri, Veronica, Xirenayi, Simayijiang, Stieglitz, Elliot, Wiita, Arun P.
Published in Transplantation and cellular therapy (01.02.2024)
Published in Transplantation and cellular therapy (01.02.2024)
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Structural surfaceomics reveals an AML-specific conformation of integrin β 2 as a CAR T cellular therapy target
Mandal, Kamal, Wicaksono, Gianina, Yu, Clinton, Adams, Jarrett J, Hoopmann, Michael R, Temple, William C, Izgutdina, Adila, Escobar, Bonell Patiño, Gorelik, Maryna, Ihling, Christian H, Nix, Matthew A, Naik, Akul, Xie, William H, Hübner, Juwita, Rollins, Lisa A, Reid, Sandy M, Ramos, Emilio, Kasap, Corynn, Steri, Veronica, Serrano, Juan Antonio Camara, Salangsang, Fernando, Phojanakong, Paul, McMillan, Melanie, Gavallos, Victor, Leavitt, Andrew D, Logan, Aaron C, Rooney, Cliona M, Eyquem, Justin, Sinz, Andrea, Huang, Benjamin J, Stieglitz, Elliot, Smith, Catherine C, Moritz, Robert L, Sidhu, Sachdev S, Huang, Lan, Wiita, Arun P
Published in Nature cancer (01.11.2023)
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Published in Nature cancer (01.11.2023)
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