Wnt signaling mediates acquisition of blood-brain barrier properties in naïve endothelium derived from human pluripotent stem cells
Gastfriend, Benjamin D, Nishihara, Hideaki, Canfield, Scott G, Foreman, Koji L, Engelhardt, Britta, Palecek, Sean P, Shusta, Eric V
Published in eLife (10.11.2021)
Published in eLife (10.11.2021)
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Journal Article
Intrinsic blood-brain barrier dysfunction contributes to multiple sclerosis pathogenesis
Nishihara, Hideaki, Perriot, Sylvain, Gastfriend, Benjamin D, Steinfort, Marel, Cibien, Celine, Soldati, Sasha, Matsuo, Kinya, Guimbal, Sarah, Mathias, Amandine, Palecek, Sean P, Shusta, Eric V, Pasquier, Renaud Du, Engelhardt, Britta
Published in Brain (London, England : 1878) (19.12.2022)
Published in Brain (London, England : 1878) (19.12.2022)
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Journal Article
PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation
Wimmer, Isabella, Tietz, Silvia, Nishihara, Hideaki, Deutsch, Urban, Sallusto, Federica, Gosselet, Fabien, Lyck, Ruth, Muller, William A, Lassmann, Hans, Engelhardt, Britta
Published in Frontiers in immunology (2019)
Published in Frontiers in immunology (2019)
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Journal Article
Therapeutic Strategies for Inflammatory Neuropathy
Nishihara, Hideaki, Kanda, Takashi
Published in Brain and nerve = Shinkei kenkyū no shinpo (01.05.2023)
Published in Brain and nerve = Shinkei kenkyū no shinpo (01.05.2023)
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Journal Article
A silicon nanomembrane platform for the visualization of immune cell trafficking across the human blood–brain barrier under flow
Mossu, Adrien, Rosito, Maria, Khire, Tejas, Li Chung, Hung, Nishihara, Hideaki, Gruber, Isabelle, Luke, Emma, Dehouck, Lucie, Sallusto, Federica, Gosselet, Fabien, McGrath, James L, Engelhardt, Britta
Published in Journal of cerebral blood flow and metabolism (01.03.2019)
Published in Journal of cerebral blood flow and metabolism (01.03.2019)
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Journal Article
Modeling Brain Vasculature Immune Interactions In Vitro
Lyck, Ruth, Nishihara, Hideaki, Aydin, Sidar, Soldati, Sasha, Engelhardt, Britta
Published in Cold Spring Harbor perspectives in medicine (01.09.2023)
Published in Cold Spring Harbor perspectives in medicine (01.09.2023)
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Journal Article
Blood-brain barrier dysfunction in immuno-mediated neurological diseases
Shimizu, Fumitaka, Nishihara, Hideaki, Kanda, Takashi
Published in Immunological medicine (03.07.2018)
Published in Immunological medicine (03.07.2018)
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Journal Article
Human CD4 + T cell subsets differ in their abilities to cross endothelial and epithelial brain barriers in vitro
Nishihara, Hideaki, Soldati, Sasha, Mossu, Adrien, Rosito, Maria, Rudolph, Henriette, Muller, William A, Latorre, Daniela, Sallusto, Federica, Sospedra, Mireia, Martin, Roland, Ishikawa, Hiroshi, Tenenbaum, Tobias, Schroten, Horst, Gosselet, Fabien, Engelhardt, Britta
Published in Fluids and barriers of the CNS (03.02.2020)
Published in Fluids and barriers of the CNS (03.02.2020)
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Journal Article
Antineutrophil cytoplasmic antibody-associated vasculitis with predominant truncal muscle weakness: a retrospective case series
Nemoto, Joe, Nishihara, Hideaki, Yasuhi, Taro, Sato, Ryota, Koga, Michiaki, Kanda, Takashi, Nakamori, Masayuki
Published in Frontiers in neurology (12.10.2023)
Published in Frontiers in neurology (12.10.2023)
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Journal Article
GRP78 antibodies damage the blood-brain barrier and relate to cerebellar degeneration in Lambert-Eaton myasthenic syndrome
Shimizu, Fumitaka, Takeshita, Yukio, Sano, Yasuteru, Hamamoto, Yuka, Shiraishi, Hirokazu, Sato, Takuya, Yoshimura, Shunsuke, Maeda, Toshihiko, Fujikawa, Susumu, Nishihara, Hideaki, Kitanosono, Hiroko, Tsujino, Akira, Motomura, Masakatsu, Kanda, Takashi
Published in Brain (London, England : 1878) (01.08.2019)
Published in Brain (London, England : 1878) (01.08.2019)
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Journal Article
The choroid plexus acts as an immune cell reservoir and brain entry site in experimental autoimmune encephalomyelitis
Lazarevic, Ivana, Soldati, Sasha, Mapunda, Josephine A, Rudolph, Henriette, Rosito, Maria, de Oliveira, Alex Cardoso, Enzmann, Gaby, Nishihara, Hideaki, Ishikawa, Hiroshi, Tenenbaum, Tobias, Schroten, Horst, Engelhardt, Britta
Published in Fluids and barriers of the CNS (01.06.2023)
Published in Fluids and barriers of the CNS (01.06.2023)
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Journal Article
Severity and patterns of blood-nerve barrier breakdown in patients with chronic inflammatory demyelinating polyradiculoneuropathy: correlations with clinical subtypes
Shimizu, Fumitaka, Sawai, Setsu, Sano, Yasuteru, Beppu, Minako, Misawa, Sonoko, Nishihara, Hideaki, Koga, Michiaki, Kuwabara, Satoshi, Kanda, Takashi
Published in PloS one (08.08.2014)
Published in PloS one (08.08.2014)
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Journal Article
Fingolimod prevents blood-brain barrier disruption induced by the sera from patients with multiple sclerosis
Nishihara, Hideaki, Shimizu, Fumitaka, Sano, Yasuteru, Takeshita, Yukio, Maeda, Toshihiko, Abe, Masaaki, Koga, Michiaki, Kanda, Takashi
Published in PloS one (16.03.2015)
Published in PloS one (16.03.2015)
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Journal Article
High levels of endothelial ICAM-1 prohibit natalizumab mediated abrogation of CD4 + T cell arrest on the inflamed BBB under flow in vitro
Soldati, Sasha, Bär, Alexander, Vladymyrov, Mykhailo, Glavin, Dale, McGrath, James L, Gosselet, Fabien, Nishihara, Hideaki, Goelz, Susan, Engelhardt, Britta
Published in Journal of neuroinflammation (23.05.2023)
Published in Journal of neuroinflammation (23.05.2023)
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Journal Article
Markedly increased IP-10 production by blood-brain barrier in neuromyelitis optica
Shimizu, Fumitaka, Nishihara, Hideaki, Sano, Yasuteru, Takeshita, Yukio, Takahashi, Shiori, Maeda, Toshihiko, Takahashi, Toshiyuki, Abe, Masaaki, Koga, Michiaki, Kanda, Takashi
Published in PloS one (26.03.2015)
Published in PloS one (26.03.2015)
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Journal Article
SARS-CoV-2 infects epithelial cells of the blood-cerebrospinal fluid barrier rather than endothelial cells or pericytes of the blood-brain barrier
Stüdle, Chiara, Nishihara, Hideaki, Wischnewski, Sven, Kulsvehagen, Laila, Perriot, Sylvain, Ishikawa, Hiroshi, Schroten, Horst, Frank, Stephan, Deigendesch, Nikolaus, Du Pasquier, Renaud, Schirmer, Lucas, Pröbstel, Anne-Katrin, Engelhardt, Britta
Published in Fluids and barriers of the CNS (24.10.2023)
Published in Fluids and barriers of the CNS (24.10.2023)
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Journal Article
Identification of galectin-3 as a possible antibody target for secondary progressive multiple sclerosis
Nishihara, Hideaki, Shimizu, Fumitaka, Kitagawa, Takao, Yamanaka, Nanami, Akada, Junko, Kuramitsu, Yasuhiro, Sano, Yasuteru, Takeshita, Yukio, Maeda, Toshihiko, Abe, Masaaki, Koga, Michiaki, Nakamura, Kazuyuki, Kanda, Takashi
Published in Multiple sclerosis (01.03.2017)
Published in Multiple sclerosis (01.03.2017)
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Journal Article
The Modular µSiM: A Mass Produced, Rapidly Assembled, and Reconfigurable Platform for the Study of Barrier Tissue Models In Vitro
McCloskey, Molly C, Kasap, Pelin, Ahmad, S Danial, Su, Shiuan-Haur, Chen, Kaihua, Mansouri, Mehran, Ramesh, Natalie, Nishihara, Hideaki, Belyaev, Yury, Abhyankar, Vinay V, Begolo, Stefano, Singer, Benjamin H, Webb, Kevin F, Kurabayashi, Katsuo, Flax, Jonathan, Waugh, Richard E, Engelhardt, Britta, McGrath, James L
Published in Advanced healthcare materials (01.09.2022)
Published in Advanced healthcare materials (01.09.2022)
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