DNA damage‐induced apoptosis and mitogen‐activated protein kinase pathway contribute to the toxicity of dronedarone in hepatic cells
Chen, Si, Ren, Zhen, Yu, Dianke, Ning, Baitang, Guo, Lei, van Benthem, J.
Published in Environmental and molecular mutagenesis (01.05.2018)
Published in Environmental and molecular mutagenesis (01.05.2018)
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Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes
LEI GUO, DIAL, Stacey, LEMING SHI, BRANHAM, William, JIE LIU, FANG, Jia-Long, GREEN, Bridgett, HELEN DENG, KAPUT, Jim, BAITANG NING
Published in Drug metabolism and disposition (01.03.2011)
Published in Drug metabolism and disposition (01.03.2011)
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Endoplasmic reticulum stress and MAPK signaling pathway activation underlie leflunomide-induced toxicity in HepG2 Cells
Ren, Zhen, Chen, Si, Qing, Tao, Xuan, Jiekun, Couch, Letha, Yu, Dianke, Ning, Baitang, Shi, Leming, Guo, Lei
Published in Toxicology (Amsterdam) (01.12.2017)
Published in Toxicology (Amsterdam) (01.12.2017)
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A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Yu, Ying, Fuscoe, James C, Zhao, Chen, Guo, Chao, Jia, Meiwen, Qing, Tao, Bannon, Desmond I, Lancashire, Lee, Bao, Wenjun, Du, Tingting, Luo, Heng, Su, Zhenqiang, Jones, Wendell D, Moland, Carrie L, Branham, William S, Qian, Feng, Ning, Baitang, Li, Yan, Hong, Huixiao, Guo, Lei, Mei, Nan, Shi, Tieliu, Wang, Kevin Y, Wolfinger, Russell D, Nikolsky, Yuri, Walker, Stephen J, Duerksen-Hughes, Penelope, Mason, Christopher E, Tong, Weida, Thierry-Mieg, Jean, Thierry-Mieg, Danielle, Shi, Leming, Wang, Charles
Published in Nature communications (10.02.2014)
Published in Nature communications (10.02.2014)
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The role of hepatic cytochrome P450s in the cytotoxicity of dronedarone
Chen, Si, Wu, Qiangen, Ning, Baitang, Bryant, Matthew, Guo, Lei
Published in Archives of toxicology (01.06.2018)
Published in Archives of toxicology (01.06.2018)
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The expression, induction and pharmacological activity of CYP1A2 are post-transcriptionally regulated by microRNA hsa-miR-132-5p
Chen, Yinting, Zeng, Linjuan, Wang, Yong, Tolleson, William H., Knox, Bridgett, Chen, Si, Ren, Zhen, Guo, Lei, Mei, Nan, Qian, Feng, Huang, Kaihong, Liu, David, Tong, Weida, Yu, Dianke, Ning, Baitang
Published in Biochemical pharmacology (01.12.2017)
Published in Biochemical pharmacology (01.12.2017)
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The role of hepatic cytochrome P450s in the cytotoxicity of sertraline
Chen, Si, Wu, Qiangen, Li, Xilin, Li, Dongying, Fan, Michelle, Ren, Zhen, Bryant, Matthew, Mei, Nan, Ning, Baitang, Guo, Lei
Published in Archives of toxicology (01.07.2020)
Published in Archives of toxicology (01.07.2020)
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Long noncoding RNA LINC00844-mediated molecular network regulates expression of drug metabolizing enzymes and nuclear receptors in human liver cells
Li, Dongying, Wu, Leihong, Knox, Bridgett, Chen, Si, Tolleson, William H., Liu, Fang, Yu, Dianke, Guo, Lei, Tong, Weida, Ning, Baitang
Published in Archives of toxicology (01.05.2020)
Published in Archives of toxicology (01.05.2020)
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A functional SNP in the 3′‐UTR of TAP2 gene interacts with microRNA hsa‐miR‐1270 to suppress the gene expression
Knox, Bridgett, Wang, Yong, Rogers, Lora J., Xuan, Jiekun, Yu, Dianke, Guan, Huaijin, Chen, Jiwei, Shi, Tieliu, Ning, Baitang, Kadlubar, Susan A., Rasoulpour, R.
Published in Environmental and molecular mutagenesis (01.03.2018)
Published in Environmental and molecular mutagenesis (01.03.2018)
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The role of CYP 3A4 and 1A1 in amiodarone-induced hepatocellular toxicity
Wu, Qiangen, Ning, Baitang, Xuan, Jiekun, Ren, Zhen, Guo, Lei, Bryant, Matthew S.
Published in Toxicology letters (24.06.2016)
Published in Toxicology letters (24.06.2016)
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A systematic evaluation of microRNAs in regulating human hepatic CYP2E1
Wang, Yong, Yu, Dianke, Tolleson, William H., Yu, Li-Rong, Green, Bridgett, Zeng, Linjuan, Chen, Yinting, Chen, Si, Ren, Zhen, Guo, Lei, Tong, Weida, Guan, Huaijin, Ning, Baitang
Published in Biochemical pharmacology (15.08.2017)
Published in Biochemical pharmacology (15.08.2017)
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Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans
Yu, Dianke, Wu, Leihong, Gill, Pritmohinder, Tolleson, William H., Chen, Si, Sun, Jinchun, Knox, Bridgett, Jin, Yaqiong, Xiao, Wenming, Hong, Huixiao, Wang, Yong, Ren, Zhen, Guo, Lei, Mei, Nan, Guo, Yongli, Yang, Xi, Shi, Leming, Chen, Yinting, Zeng, Linjuan, Dreval, Kostiantyn, Tryndyak, Volodymyr, Pogribny, Igor, Fang, Hong, Shi, Tieliu, McCullough, Sandra, Bhattacharyya, Sudeepa, Schnackenberg, Laura, Mattes, William, Beger, Richard D., James, Laura, Tong, Weida, Ning, Baitang
Published in Archives of toxicology (01.02.2018)
Published in Archives of toxicology (01.02.2018)
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microRNAs as pharmacogenomic biomarkers for drug efficacy and drug safety assessment
Koturbash, Igor, Tolleson, William H, Guo, Lei, Yu, Dianke, Chen, Si, Hong, Huixiao, Mattes, William, Ning, Baitang
Published in Biomarkers in medicine (01.01.2015)
Published in Biomarkers in medicine (01.01.2015)
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X-CNV: genome-wide prediction of the pathogenicity of copy number variations
Zhang, Li, Shi, Jingru, Ouyang, Jian, Zhang, Riquan, Tao, Yiran, Yuan, Dongsheng, Lv, Chengkai, Wang, Ruiyuan, Ning, Baitang, Roberts, Ruth, Tong, Weida, Liu, Zhichao, Shi, Tieliu
Published in Genome medicine (18.08.2021)
Published in Genome medicine (18.08.2021)
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Characterization of cytochrome P450s (CYP)-overexpressing HepG2 cells for assessing drug and chemical-induced liver toxicity
Chen, Si, Wu, Qiangen, Li, Xilin, Li, Dongying, Mei, Nan, Ning, Baitang, Puig, Montserrat, Ren, Zhen, Tolleson, William H, Guo, Lei
Published in Journal of environmental science and health. Part C: Toxicology and carcinogenesis (2021)
Published in Journal of environmental science and health. Part C: Toxicology and carcinogenesis (2021)
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Cross-platform comparison of SYBR Green real-time PCR with TaqMan PCR, microarrays and other gene expression measurement technologies evaluated in the MicroArray Quality Control (MAQC) study
Arikawa, Emi, Sun, Yanyang, Wang, Jie, Zhou, Qiong, Ning, Baitang, Dial, Stacey L, Guo, Lei, Yang, Jingping
Published in BMC genomics (11.07.2008)
Published in BMC genomics (11.07.2008)
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The Development of a Database for Herbal and Dietary Supplement Induced Liver Toxicity
Zhu, Jieqiang, Seo, Ji-Eun, Wang, Sanlong, Ashby, Kristin, Ballard, Rodney, Yu, Dianke, Ning, Baitang, Agarwal, Rajiv, Borlak, Jürgen, Tong, Weida, Chen, Minjun
Published in International journal of molecular sciences (28.09.2018)
Published in International journal of molecular sciences (28.09.2018)
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Sequencing XMET genes to promote genotype-guided risk assessment and precision medicine
Jin, Yaqiong, Chen, Geng, Xiao, Wenming, Hong, Huixiao, Xu, Joshua, Guo, Yongli, Xiao, Wenzhong, Shi, Tieliu, Shi, Leming, Tong, Weida, Ning, Baitang
Published in Science China. Life sciences (01.07.2019)
Published in Science China. Life sciences (01.07.2019)
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Gene expression variability in human hepatic drug metabolizing enzymes and transporters
Yang, Lun, Price, Elvin T, Chang, Ching-Wei, Li, Yan, Huang, Ying, Guo, Li-Wu, Guo, Yongli, Kaput, Jim, Shi, Leming, Ning, Baitang
Published in PloS one (23.04.2013)
Published in PloS one (23.04.2013)
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