An amyloid-β protofibril-selective antibody prevents amyloid formation in a mouse model of Alzheimer's disease
Lord, Anna, Gumucio, Astrid, Englund, Hillevi, Sehlin, Dag, Sundquist, Valentina Screpanti, Söderberg, Linda, Möller, Christer, Gellerfors, Pär, Lannfelt, Lars, Pettersson, Frida Ekholm, Nilsson, Lars N.G
Published in Neurobiology of disease (01.12.2009)
Published in Neurobiology of disease (01.12.2009)
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Cognitive impairment in PDAPP mice depends on ApoE and ACT-catalyzed amyloid formation
Nilsson, Lars N.G, Arendash, Gary W, Leighty, Ralph E, Costa, David A, Low, Mark A, Garcia, Marcos F, Cracciolo, Jennifer R, Rojiani, Amyn, Wu, Xin, Bales, Kelly R, Paul, Steven M, Potter, Huntington
Published in Neurobiology of aging (01.10.2004)
Published in Neurobiology of aging (01.10.2004)
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Cerebrospinal fluid sTREM2 in Alzheimer's disease: comparisons between clinical presentation and AT classification
Knapskog, Anne-Brita, Henjum, Kristi, Idland, Ane-Victoria, Eldholm, Rannveig Sakshaug, Persson, Karin, Saltvedt, Ingvild, Watne, Leiv Otto, Engedal, Knut, Nilsson, Lars N G
Published in Scientific reports (28.09.2020)
Published in Scientific reports (28.09.2020)
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Loss of Astrocyte Polarization in the Tg-ArcSwe Mouse Model of Alzheimer's Disease
Yang, Jing, Lunde, Lisa K., Nuntagij, Paworn, Oguchi, Tomohiro, Camassa, Laura M.A., Nilsson, Lars N.G., Lannfelt, Lars, Xu, Yuming, Amiry-Moghaddam, Mahmood, Ottersen, Ole Petter, Torp, Reidun
Published in Journal of Alzheimer's disease (01.01.2011)
Published in Journal of Alzheimer's disease (01.01.2011)
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Sensitive ELISA detection of amyloid-β protofibrils in biological samples
Englund, Hillevi, Sehlin, Dag, Johansson, Ann-Sofi, Nilsson, Lars N.G, Gellerfors, Pär, Paulie, Staffan, Lannfelt, Lars, Pettersson, Frida Ekholm
Published in Journal of neurochemistry (01.10.2007)
Published in Journal of neurochemistry (01.10.2007)
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Isobaric Quantification of Cerebrospinal Fluid Amyloid‑β Peptides in Alzheimer’s Disease: C‑Terminal Truncation Relates to Early Measures of Neurodegeneration
Rogeberg, Magnus, Almdahl, Ina Selseth, Wettergreen, Marianne, Nilsson, Lars N.G, Fladby, Tormod
Published in Journal of proteome research (06.11.2015)
Published in Journal of proteome research (06.11.2015)
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A highly insoluble state of Aβ similar to that of Alzheimer's disease brain is found in Arctic APP transgenic mice
Philipson, Ola, Hammarström, Per, Nilsson, K. Peter R, Portelius, Erik, Olofsson, Tommie, Ingelsson, Martin, Hyman, Bradley T, Blennow, Kaj, Lannfelt, Lars, Kalimo, Hannu, Nilsson, Lars N.G
Published in Neurobiology of aging (01.09.2009)
Published in Neurobiology of aging (01.09.2009)
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Amyloid-β protofibril levels correlate with spatial learning in Arctic Alzheimer's disease transgenic mice
Lord, Anna, Englund, Hillevi, Söderberg, Linda, Tucker, Stina, Clausen, Fredrik, Hillered, Lars, Gordon, Marcia, Morgan, Dave, Lannfelt, Lars, Pettersson, Frida E, Nilsson, Lars N.G
Published in The FEBS journal (01.02.2009)
Published in The FEBS journal (01.02.2009)
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Journal Article
A high cerebrospinal fluid soluble TREM2 level is associated with slow clinical progression of Alzheimer's disease
Edwin, Trine Holt, Henjum, Kristi, Nilsson, Lars N.G., Watne, Leiv Otto, Persson, Karin, Eldholm, Rannveig Sakshaug, Saltvedt, Ingvild, Halaas, Nathalie Bodd, Selbæk, Geir, Engedal, Knut, Strand, Bjørn Heine, Knapskog, Anne‐Brita
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (2020)
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (2020)
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Journal Article
Brainwide distribution and variance of amyloid-beta deposits in tg-ArcSwe mice
Lillehaug, Sveinung, Syverstad, Gry H, Nilsson, Lars N.G, Bjaalie, Jan G, Leergaard, Trygve B, Torp, Reidun
Published in Neurobiology of aging (01.03.2014)
Published in Neurobiology of aging (01.03.2014)
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Journal Article
Observations in APP Bitransgenic Mice Suggest that Diffuse and Compact Plaques Form via Independent Processes in Alzheimer's Disease
Lord, Anna, Philipson, Ola, Klingstedt, Therése, Westermark, Gunilla, Hammarström, Per, Nilsson, K. Peter R, Nilsson, Lars N.G
Published in The American journal of pathology (01.05.2011)
Published in The American journal of pathology (01.05.2011)
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The Arctic amyloid-β precursor protein (AβPP) mutation results in distinct plaques and accumulation of N- and C-truncated Aβ
Philipson, Ola, Lord, Anna, Lalowski, Maciej, Soliymani, Rabah, Baumann, Marc, Thyberg, Johan, Bogdanovic, Nenad, Olofsson, Tommie, Tjernberg, Lars O, Ingelsson, Martin, Lannfelt, Lars, Kalimo, Hannu, Nilsson, Lars N.G
Published in Neurobiology of aging (01.05.2012)
Published in Neurobiology of aging (01.05.2012)
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Genetic deletion and pharmacological inhibition of Nogo-66 receptor impairs cognitive outcome after traumatic brain injury in mice
Hånell, Anders, Clausen, Fredrik, Björk, Maria, Jansson, Kristine, Philipson, Ola, Nilsson, Lars N G, Hillered, Lars, Weinreb, Paul H, Lee, Daniel, McIntosh, Tracy K, Gimbel, David A, Strittmatter, Stephen M, Marklund, Niklas
Published in Journal of neurotrauma (01.07.2010)
Published in Journal of neurotrauma (01.07.2010)
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Journal Article
Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5'-untranslated region sequences
Rogers, J T, Leiter, L M, McPhee, J, Cahill, C M, Zhan, S S, Potter, H, Nilsson, L N
Published in The Journal of biological chemistry (05.03.1999)
Published in The Journal of biological chemistry (05.03.1999)
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Journal Article
P1-097: The arctic Alzheimer mutation alters structure and composition of Aβ deposits
Philipson, Ola, Lord, Anna, Olofsson, Tommie, Ingelsson, Martin, Lannfelt, Lars, Kalimo, Hannu, Nilsson, Lars N.G
Published in Alzheimer's & dementia (01.07.2008)
Published in Alzheimer's & dementia (01.07.2008)
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Use of multimetric statistical analysis to characterize and discriminate between the performance of four Alzheimer’s transgenic mouse lines differing in Aβ deposition
Leighty, Ralph E, Nilsson, Lars N.G, Potter, Huntington, Costa, David A, Low, Mark A, Bales, Kelly R, Paul, Steven M, Arendash, Gary W
Published in Behavioural brain research (12.08.2004)
Published in Behavioural brain research (12.08.2004)
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Journal Article
Increased mRNA Levels of TCF7L2 and MYC of the Wnt Pathway in Tg-ArcSwe Mice and Alzheimer's Disease Brain
Wang, Yijing, Blom, Elin S., Skoglund, Lena, Hansson, Anita C., Ubaldi, Massimo, Lourdusamy, Anbarasu, Sommer, Wolfgang H., Mielke, Matthew, Hyman, Bradley T., Heilig, Markus, Lannfelt, Lars, Nilsson, Lars N. G., Ingelsson, Martin
Published in International journal of alzheimer's disease (2011)
Published in International journal of alzheimer's disease (2011)
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O3-02-04: Increased levels of CSF Aβ oligomers in Alzheimer's disease: Combination of techniques allows indirect estimates
Englund, Hillevi, Sehlin, Dag, Gunnarsson, Malin Degerman, Lord, Anna, Brundin, RoseMarie, Ingelsson, Martin, Kilander, Lena, Nilsson, Lars N.G, Pettersson, Frida Ekholm, Lannfelt, Lars
Published in Alzheimer's & dementia (01.07.2008)
Published in Alzheimer's & dementia (01.07.2008)
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