Mammalian mitochondrial complex I: biogenesis, regulation, and reactive oxygen species generation
Koopman, Werner J H, Nijtmans, Leo G J, Dieteren, Cindy E J, Roestenberg, Peggy, Valsecchi, Federica, Smeitink, Jan A M, Willems, Peter H G M
Published in Antioxidants & redox signaling (15.06.2010)
Published in Antioxidants & redox signaling (15.06.2010)
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Identification of Mitochondrial Complex I Assembly Intermediates by Tracing Tagged NDUFS3 Demonstrates the Entry Point of Mitochondrial Subunits
Vogel, Rutger O., Dieteren, Cindy E.J., van den Heuvel, Lambert P. W.J., Willems, Peter H. G.M., Smeitink, Jan A.M., Koopman, Werner J.H., Nijtmans, Leo G.J.
Published in The Journal of biological chemistry (09.03.2007)
Published in The Journal of biological chemistry (09.03.2007)
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Journal Article
Prohibitins act as a membrane-bound chaperone for the stabilization of mitochondrial proteins
Nijtmans, Leo G.J., de Jong, Liesbeth, Artal Sanz, Marta, Coates, Philip J., Berden, Jan A., Back, Jaap Willem, Muijsers, Anton O., van der Spek, Hans, Grivell, Les A.
Published in The EMBO journal (01.06.2000)
Published in The EMBO journal (01.06.2000)
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Journal Article
Subunits of Mitochondrial Complex I Exist as Part of Matrix- and Membrane-associated Subcomplexes in Living Cells
Dieteren, Cindy E.J., Willems, Peter H.G.M., Vogel, Rutger O., Swarts, Herman G., Fransen, Jack, Roepman, Ronald, Crienen, Gijs, Smeitink, Jan A.M., Nijtmans, Leo G.J., Koopman, Werner J.H.
Published in The Journal of biological chemistry (12.12.2008)
Published in The Journal of biological chemistry (12.12.2008)
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Journal Article
Defective mitochondrial translation differently affects the live cell dynamics of complex I subunits
Dieteren, Cindy E.J., Willems, Peter H.G.M., Swarts, Herman G., Fransen, Jack, Smeitink, Jan A.M., Koopman, Werner J.H., Nijtmans, Leo G.J.
Published in Biochimica et biophysica acta (01.12.2011)
Published in Biochimica et biophysica acta (01.12.2011)
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Journal Article
Human mitochondrial complex I assembly: A dynamic and versatile process
Vogel, Rutger O., Smeitink, Jan A.M., Nijtmans, Leo G.J.
Published in Biochimica et biophysica acta (01.10.2007)
Published in Biochimica et biophysica acta (01.10.2007)
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Journal Article
Blue Native electrophoresis to study mitochondrial and other protein complexes
Nijtmans, Leo G.J, Henderson, Nadine S, Holt, Ian J
Published in Methods (San Diego, Calif.) (01.04.2002)
Published in Methods (San Diego, Calif.) (01.04.2002)
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Journal Article
Metabolic consequences of NDUFS4 gene deletion in immortalized mouse embryonic fibroblasts
Valsecchi, Federica, Monge, Claire, Forkink, Marleen, de Groof, Ad J.C., Benard, Giovanni, Rossignol, Rodrigue, Swarts, Herman G., van Emst-de Vries, Sjenet E., Rodenburg, Richard J., Calvaruso, Maria A., Nijtmans, Leo G.J., Heeman, Bavo, Roestenberg, Peggy, Wieringa, Be, Smeitink, Jan A.M., Koopman, Werner J.H., Willems, Peter H.G.M.
Published in Biochimica et biophysica acta (01.10.2012)
Published in Biochimica et biophysica acta (01.10.2012)
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Journal Article
Solute diffusion is hindered in the mitochondrial matrix
Dieteren, Cindy E.J, Gielen, Stan C.A.M, Nijtmans, Leo G.J, Smeitink, Jan A.M, Swarts, Herman G, Brock, Roland, Willems, Peter H.G.M, Koopman, Werner J.H
Published in Proceedings of the National Academy of Sciences - PNAS (24.05.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (24.05.2011)
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Superoxide production is inversely related to complex I activity in inherited complex I deficiency
Verkaart, Sjoerd, Koopman, Werner J.H., van Emst-de Vries, Sjenet E., Nijtmans, Leo G.J., van den Heuvel, Lambertus W.P.J., Smeitink, Jan A.M., Willems, Peter H.G.M.
Published in Biochimica et biophysica acta (01.03.2007)
Published in Biochimica et biophysica acta (01.03.2007)
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Journal Article
Differences in assembly or stability of complex I and other mitochondrial OXPHOS complexes in inherited complex I deficiency
Ugalde, Cristina, Janssen, Rolf J.R.J., van den Heuvel, Lambert P., Smeitink, Jan A.M., Nijtmans, Leo G.J.
Published in Human molecular genetics (15.03.2004)
Published in Human molecular genetics (15.03.2004)
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The Mitochondrial Prohibitin Complex Is Essential for Embryonic Viability and Germline Function in Caenorhabditis elegans
Sanz, Marta Artal, Tsang, William Y., Willems, Esther M., Grivell, Les A., Lemire, Bernard D., van der Spek, Hans, Nijtmans, Leo G.J.
Published in The Journal of biological chemistry (22.08.2003)
Published in The Journal of biological chemistry (22.08.2003)
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Journal Article
Mitigation of NADH: Ubiquinone oxidoreductase deficiency by chronic Trolox treatment
Koopman, Werner J.H., Verkaart, Sjoerd, van Emst-de Vries, Sjenet E., Grefte, Sander, Smeitink, Jan A.M., Nijtmans, Leo G.J., Willems, Peter H.G.M.
Published in Biochimica et biophysica acta (01.07.2008)
Published in Biochimica et biophysica acta (01.07.2008)
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Journal Article
A structure for the yeast prohibitin complex: Structure prediction and evidence from chemical crosslinking and mass spectrometry
Back, Jaap W., Sanz, Marta Artal, de Jong, Luitzen, de Koning, Leo J., Nijtmans, Leo G.J., de Koster, Chris G., Grivell, Les A., van der Spek, Hans, Muijsers, Anton O.
Published in Protein science (01.10.2002)
Published in Protein science (01.10.2002)
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Investigation of the complex I assembly chaperones B17.2L and NDUFAF1 in a cohort of CI deficient patients
Vogel, Rutger O., van den Brand, Mariël A.M., Rodenburg, Richard J., van den Heuvel, Lambert P.W.J., Tsuneoka, Makoto, Smeitink, Jan A.M., Nijtmans, Leo G.J.
Published in Molecular genetics and metabolism (01.06.2007)
Published in Molecular genetics and metabolism (01.06.2007)
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Contiguous gene deletion of ELOVL7, ERCC8 and NDUFAF2 in a patient with a fatal multisystem disorder
Janssen, Rolf J.R.J., Distelmaier, Felix, Smeets, Roel, Wijnhoven, Tessa, Østergaard, Elsebet, Jaspers, Nicolaas G.J., Raams, Anja, Kemp, Stephan, Rodenburg, Richard J.T., Willems, Peter H.M.G., van den Heuvel, Lambert P.W.J., Smeitink, Jan A.M., Nijtmans, Leo G.J.
Published in Human molecular genetics (15.09.2009)
Published in Human molecular genetics (15.09.2009)
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Journal Article
Mitochondrial assembly in yeast
Grivell, Les A, Artal-Sanz, Marta, Hakkaart, Gertjan, de Jong, Liesbeth, Nijtmans, Leo G.J, van Oosterum, Katinka, Siep, Michel, van der Spek, Hans
Published in FEBS letters (04.06.1999)
Published in FEBS letters (04.06.1999)
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TMEM70 functions in the assembly of complexes I and V
Sánchez-Caballero, Laura, Elurbe, Dei M., Baertling, Fabian, Guerrero-Castillo, Sergio, van den Brand, Mariel, van Strien, Joeri, van Dam, Teunis J.P., Rodenburg, Richard, Brandt, Ulrich, Huynen, Martijn A., Nijtmans, Leo G.J.
Published in Biochimica et biophysica acta. Bioenergetics (01.08.2020)
Published in Biochimica et biophysica acta. Bioenergetics (01.08.2020)
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TEFM (c17orf42) is necessary for transcription of human mtDNA
Minczuk, Michal, He, Jiuya, Duch, Anna M, Ettema, Thijs J, Chlebowski, Aleksander, Dzionek, Karol, Nijtmans, Leo G J, Huynen, Martijn A, Holt, Ian J
Published in Nucleic acids research (01.05.2011)
Published in Nucleic acids research (01.05.2011)
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