Spatiotemporal regulation of clonogenicity in colorectal cancer xenografts
van der Heijden, Maartje, Miedema, Daniël M., Waclaw, Bartlomiej, Veenstra, Veronique L., Lecca, Maria C., Nijman, Lisanne E., van Dijk, Erik, van Neerven, Sanne M., Lodestijn, Sophie C., Lenos, Kristiaan J., de Groot, Nina E., Prasetyanti, Pramudita R., Varea, Andrea Arricibita, Winton, Douglas J., Medema, Jan Paul, Morrissey, Edward, Ylstra, Bauke, Nowak, Martin A., Bijlsma, Maarten F., Vermeulen, Louis
Published in Proceedings of the National Academy of Sciences - PNAS (26.03.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (26.03.2019)
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Chromosomal copy number heterogeneity predicts survival rates across cancers
van Dijk, Erik, van den Bosch, Tom, Lenos, Kristiaan J., El Makrini, Khalid, Nijman, Lisanne E., van Essen, Hendrik F. B., Lansu, Nico, Boekhout, Michiel, Hageman, Joris H., Fitzgerald, Rebecca C., Punt, Cornelis J. A., Tuynman, Jurriaan B., Snippert, Hugo J. G., Kops, Geert J. P. L., Medema, Jan Paul, Ylstra, Bauke, Vermeulen, Louis, Miedema, Daniël M.
Published in Nature communications (27.05.2021)
Published in Nature communications (27.05.2021)
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Continuous clonal labeling reveals uniform progenitor potential in the adult exocrine pancreas
Lodestijn, Sophie C., van den Bosch, Tom, Nijman, Lisanne E., Moreno, Leandro F., Schlingemann, Sophie, Sheraton, Vivek M., van Neerven, Sanne M., Koning, Jasper J., Vieira Braga, Felipe A., Paauw, Nanne J., Lecca, Maria C., Lenos, Kristiaan J., Morrissey, Edward, Miedema, Daniël M., Winton, Douglas J., Bijlsma, Maarten F., Vermeulen, Louis
Published in Cell stem cell (04.11.2021)
Published in Cell stem cell (04.11.2021)
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Marker-free lineage tracing reveals an environment-instructed clonogenic hierarchy in pancreatic cancer
Lodestijn, Sophie C., Miedema, Daniël M., Lenos, Kristiaan J., Nijman, Lisanne E., Belt, Saskia C., El Makrini, Khalid, Lecca, Maria C., Waasdorp, Cynthia, van den Bosch, Tom, Bijlsma, Maarten F., Vermeulen, Louis
Published in Cell reports (Cambridge) (19.10.2021)
Published in Cell reports (Cambridge) (19.10.2021)
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Intestinal Apc‐inactivation induces HSP25 dependency
van Neerven, Sanne M, Smit, Wouter L, van Driel, Milou S, Kakkar, Vaishali, de Groot, Nina E, Nijman, Lisanne E, Elbers, Clara C, Léveillé, Nicolas, Heijmans, Jarom, Vermeulen, Louis
Published in EMBO molecular medicine (07.12.2022)
Published in EMBO molecular medicine (07.12.2022)
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Subtype-specific kinase dependency regulates growth and metastasis of poor-prognosis mesenchymal colorectal cancer
Buikhuisen, Joyce Y, Gomez Barila, Patricia M, Cameron, Kate, Suijkerbuijk, Saskia J E, Lieftink, Cor, di Franco, Simone, Krotenberg Garcia, Ana, Uceda Castro, Rebeca, Lenos, Kristiaan J, Nijman, Lisanne E, Torang, Arezo, Longobardi, Ciro, de Jong, Joan H, Dekker, Daniëlle, Stassi, Giorgio, Vermeulen, Louis, Beijersbergen, Roderick L, van Rheenen, Jacco, Huveneers, Stephan, Medema, Jan Paul
Published in Journal of experimental & clinical cancer research (03.03.2023)
Published in Journal of experimental & clinical cancer research (03.03.2023)
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The Effect of Dynamic, In Vivo-like Oxaliplatin on HCT116 Spheroids in a Cancer-on-Chip Model Is Representative of the Response in Xenografts
Komen, Job, van Neerven, Sanne M, Bossink, Elsbeth G B M, de Groot, Nina E, Nijman, Lisanne E, van den Berg, Albert, Vermeulen, Louis, van der Meer, Andries D
Published in Micromachines (Basel) (06.05.2022)
Published in Micromachines (Basel) (06.05.2022)
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Apc-mutant cells act as supercompetitors in intestinal tumour initiation
van Neerven, Sanne M., de Groot, Nina E., Nijman, Lisanne E., Scicluna, Brendon P., van Driel, Milou S., Lecca, Maria C., Warmerdam, Daniël O., Kakkar, Vaishali, Moreno, Leandro F., Vieira Braga, Felipe A., Sanches, Delano R., Ramesh, Prashanthi, ten Hoorn, Sanne, Aelvoet, Arthur S., van Boxel, Marouska F., Koens, Lianne, Krawczyk, Przemek M., Koster, Jan, Dekker, Evelien, Medema, Jan Paul, Winton, Douglas J., Bijlsma, Maarten F., Morrissey, Edward, Léveillé, Nicolas, Vermeulen, Louis
Published in Nature (London) (17.06.2021)
Published in Nature (London) (17.06.2021)
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Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer
Lenos, Kristiaan J., Miedema, Daniël M., Lodestijn, Sophie C., Nijman, Lisanne E., van den Bosch, Tom, Romero Ros, Xavier, Lourenço, Filipe C., Lecca, Maria C., van der Heijden, Maartje, van Neerven, Sanne M., van Oort, Anita, Leveille, Nicolas, Adam, Ronja S., de Sousa E Melo, Felipe, Otten, Joy, Veerman, Patrick, Hypolite, Guillaume, Koens, Lianne, Lyons, Scott K., Stassi, Giorgio, Winton, Douglas J., Medema, Jan Paul, Morrissey, Edward, Bijlsma, Maarten F., Vermeulen, Louis
Published in Nature cell biology (01.10.2018)
Published in Nature cell biology (01.10.2018)
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A mouse model for peritoneal metastases of colorectal origin recapitulates patient heterogeneity
Bastiaenen, Vivian P., Klaver, Charlotte E.L., van der Heijden, Maartje C.S., Nijman, Lisanne E., Lecca, Maria C., Tanis, Pieter J., Lenos, Kristiaan J., Vermeulen, Louis
Published in Laboratory investigation (01.11.2020)
Published in Laboratory investigation (01.11.2020)
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A consensus molecular subtypes classification strategy for clinical colorectal cancer tissues
de Back, Tim R, Wu, Tan, Schafrat, Pascale Jm, Ten Hoorn, Sanne, Tan, Miaomiao, He, Lingli, van Hooff, Sander R, Koster, Jan, Nijman, Lisanne E, Vink, Geraldine R, Beumer, Inès J, Elbers, Clara C, Lenos, Kristiaan J, Sommeijer, Dirkje W, Wang, Xin, Vermeulen, Louis
Published in Life science alliance (01.08.2024)
Published in Life science alliance (01.08.2024)
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Caffeine Limits Expansion of Apc-Deficient Clones in the Intestine by NOTUM Inhibition
van Driel, Milou S., Linssen, Jasmijn D.G., Flanagan, Dustin J., Vlahov, Nikola, Nijman, Lisanne E., de Groot, Nina E., Elbers, Clara C., Koster, Jan, Sansom, Owen J., Vermeulen, Louis, van Neerven, Sanne M.
Published in Cellular and molecular gastroenterology and hepatology (01.01.2023)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2023)
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Exploiting a subtype-specific mitochondrial vulnerability for successful treatment of colorectal peritoneal metastases
Bootsma, Sanne, Dings, Mark P.G., Kesselaar, Job, Helderman, Roxan F.C.P.A., van Megesen, Kyah, Constantinides, Alexander, Moreno, Leandro Ferreira, Stelloo, Ellen, Scutigliani, Enzo M., Bokan, Bella, Torang, Arezo, van Hooff, Sander R., Zwijnenburg, Danny A., Wouters, Valérie M., van de Vlasakker, Vincent C.J., Galanos, Laskarina J.K., Nijman, Lisanne E., Logiantara, Adrian, Veenstra, Veronique L., Schlingemann, Sophie, van Piggelen, Sterre, van der Wel, Nicole, Krawczyk, Przemek M., Platteeuw, Johannes J., Tuynman, Jurriaan B., de Hingh, Ignace H., Klomp, Jan P.G., Oubrie, Arthur, Snaebjornsson, Petur, Medema, Jan Paul, Oei, Arlene L., Kranenburg, Onno, Elbers, Clara C., Lenos, Kristiaan J., Vermeulen, Louis, Bijlsma, Maarten F.
Published in Cell reports. Medicine (21.05.2024)
Published in Cell reports. Medicine (21.05.2024)
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Molecular characterization of colorectal cancer related peritoneal metastatic disease
Lenos, Kristiaan J., Bach, Sander, Ferreira Moreno, Leandro, ten Hoorn, Sanne, Sluiter, Nina R., Bootsma, Sanne, Vieira Braga, Felipe A., Nijman, Lisanne E., van den Bosch, Tom, Miedema, Daniel M., van Dijk, Erik, Ylstra, Bauke, Kulicke, Ruth, Davis, Fred P., Stransky, Nicolas, Smolen, Gromoslaw A., Coebergh van den Braak, Robert R. J., IJzermans, Jan N. M., Martens, John W. M., Hallam, Sally, Beggs, Andrew D., Kops, Geert J. P. L., Lansu, Nico, Bastiaenen, Vivian P., Klaver, Charlotte E. L., Lecca, Maria C., El Makrini, Khalid, Elbers, Clara C., Dings, Mark P. G., van Noesel, Carel J. M., Kranenburg, Onno, Medema, Jan Paul, Koster, Jan, Koens, Lianne, Punt, Cornelis J. A., Tanis, Pieter J., de Hingh, Ignace H., Bijlsma, Maarten F., Tuynman, Jurriaan B., Vermeulen, Louis
Published in Nature communications (04.08.2022)
Published in Nature communications (04.08.2022)
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Correction: A consensus molecular subtypes classification strategy for clinical colorectal cancer tissues
de Back, Tim R, Wu, Tan, Schafrat, Pascale Jm, Ten Hoorn, Sanne, Tan, Miaomiao, He, Lingli, van Hooff, Sander R, Koster, Jan, Nijman, Lisanne E, Vink, Geraldine R, Beumer, Inès J, Elbers, Clara C, Lenos, Kristiaan J, Sommeijer, Dirkje W, Wang, Xin, Vermeulen, Louis
Published in Life science alliance (01.09.2024)
Published in Life science alliance (01.09.2024)
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