Multispecific Organic Anion Transporter Is Responsible for the Biliary Excretion of the Camptothecin Derivative Irinotecan and its Metabolites in Rats
Chu, X Y, Kato, Y, Niinuma, K, Sudo, K I, Hakusui, H, Sugiyama, Y
Published in The Journal of pharmacology and experimental therapeutics (01.04.1997)
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Published in The Journal of pharmacology and experimental therapeutics (01.04.1997)
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Temocaprilat, a Novel Angiotensin-Converting Enzyme Inhibitor, is Excreted in Bile via an ATP-dependent Active Transporter (cMOAT) That is Deficient in Eisai Hyperbilirubinemic Mutant Rats (EHBR)
Ishizuka, H, Konno, K, Naganuma, H, Sasahara, K, Kawahara, Y, Niinuma, K, Suzuki, H, Sugiyama, Y
Published in The Journal of pharmacology and experimental therapeutics (01.03.1997)
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Published in The Journal of pharmacology and experimental therapeutics (01.03.1997)
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Primary active transport of organic anions on bile canalicular membrane in humans
Niinuma, K, Kato, Y, Suzuki, H, Tyson, C A, Weizer, V, Dabbs, J E, Froehlich, R, Green, C E, Sugiyama, Y
Published in American journal of physiology: Gastrointestinal and liver physiology (01.05.1999)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.05.1999)
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Biliary excretion mechanism of CPT-11 and its metabolites in humans : Involvement of primary active transporters
CHU, X.-Y, KATO, Y, SUGIYAMA, Y, UEDA, K, SUZUKI, H, NIINUMA, K, TYSON, C. A, WEIZER, V, DABBS, J. E, FROEHLICH, R, GREEN, C. E
Published in Cancer research (Chicago, Ill.) (15.11.1998)
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Published in Cancer research (Chicago, Ill.) (15.11.1998)
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CARRIER-MEDIATED HEPATIC UPTAKE OF THE CATIONIC CYCLOPEPTIDE, OCTREOTIDE, IN RATS
Tadashi Yamada, Kayoko Niinuma, Michel Lemaire, Tetsuya Terasaki, Yuichi Sugiyama
Published in Drug metabolism and disposition (01.05.1997)
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Published in Drug metabolism and disposition (01.05.1997)
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Kinetic Analysis of the Primary Active Transport of Conjugated Metabolites Across the Bile Canalicular Membrane: Comparative Study ofS-(2,4-Dinitrophenyl)-glutathione and 6-Hydroxy-5,7-dimethyl-2-methylamino4-(3-pyridylmethyl)benzothiazole Glucuronide
Kayoko Niinuma, Osamu Takenaka, Toru Horie, Kazuo Kobayashi, Yukio Kato, Hiroshi Suzuki, Yuichi Sugiyama
Published in The Journal of pharmacology and experimental therapeutics (01.08.1997)
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Published in The Journal of pharmacology and experimental therapeutics (01.08.1997)
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Hepatobiliary transport mechanism for the cyclopentapeptide endothelin antagonist BQ-123
Shin, H C, Kato, Y, Yamada, T, Niinuma, K, Hisaka, A, Sugiyama, Y
Published in The American journal of physiology (01.05.1997)
Published in The American journal of physiology (01.05.1997)
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Methotrexate is excreted into the bile by canalicular multispecific organic anion transporter in rats
MASUDA, M, I'IZUKA, Y, YAMAZAKI, M, NISHIGAKI, R, KATO, Y, NI'INUMA, K, SUZUKI, H, SUGIYAMA, Y
Published in Cancer research (Chicago, Ill.) (15.08.1997)
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Published in Cancer research (Chicago, Ill.) (15.08.1997)
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Primary active transport of organic anions on bile canalicular membrane in humans
NIINUMA, K, KATO, Y, SUZUKI, H, TYSON, C. A, WEIZER, V, DABBS, J. E, FROEHLICH, R, GREEN, C. E, SUGIYAMA, Y
Published in American journal of physiology: Gastrointestinal and liver physiology (01.05.1999)
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Published in American journal of physiology: Gastrointestinal and liver physiology (01.05.1999)
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Biliary Excretion of Pravastatin in Rats: Contribution of the excretion pathway mediated by canalicular multispecific organic anion transporter (cMOAT)
YAMAZAKI, M, AKIYAMA, S, NI'INUMA, K, NISHIGAKI, R, SUGIYAMA, Y
Published in Drug metabolism and disposition (01.10.1997)
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Published in Drug metabolism and disposition (01.10.1997)
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Which concentration of the inhibitor should be used to predict in vivo drug interactions from in vitro data?
Ito, Kiyomi, Chiba, Koji, Horikawa, Masato, Ishigami, Michi, Mizuno, Naomi, Aoki, Jun, Gotoh, Yasumasa, Iwatsubo, Takafumi, Kanamitsu, Shin-ichi, Kato, Motohiro, Kawahara, Iichiro, Niinuma, Kayoko, Nishino, Akiko, Sato, Norihito, Tsukamoto, Yuko, Ueda, Kaoru, Itoh, Tomoo, Sugiyama, Yuichi
Published in AAPS PharmSci (01.01.2002)
Published in AAPS PharmSci (01.01.2002)
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Journal Article
Primary active transport of organic anions on bile canalicular membrane in humans
Niinuma, Kayoko, Kato, Yukio, Suzuki, Hiroshi, Tyson, Charles A, Weizer, Valorie, Dabbs, Jack E, Froehlich, Ritchie, Green, Carol E, Sugiyama, Yuichi
Published in American journal of physiology: Gastrointestinal and liver physiology (01.05.1999)
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Published in American journal of physiology: Gastrointestinal and liver physiology (01.05.1999)
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Phase-3 Detoxification in the Liver: Biliary Excretion of small molecules and peptides by primary active transport mechanisms
SUGIYAMA, Yuichi, YAMADA, Tadashi, NIINUMA, Kayoko, SHIN, Ho-Chul, HISAKA, Akihiro, YAMAZAKI, Masayo, KATO, Yukio, TERASAKI, Tetsuya, SUZUKI, Hiroshi
Published in Yakubutsu dōtai = Xenobiotic metabolism and disposition (1995)
Published in Yakubutsu dōtai = Xenobiotic metabolism and disposition (1995)
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