G Protein-Coupled Receptors: Dynamic Machines for Signaling Pain and Itch
Geppetti, Pierangelo, Veldhuis, Nicholas A., Lieu, TinaMarie, Bunnett, Nigel W.
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Published in Neuron (Cambridge, Mass.) (18.11.2015)
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Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome
Jimenez-Vargas, Nestor N., Pattison, Luke A., Zhao, Peishen, Lieu, TinaMarie, Latorre, Rocco, Jensen, Dane D., Castro, Joel, Aurelio, Luigi, Le, Giang T., Flynn, Bernard, Herenbrink, Carmen Klein, Yeatman, Holly R., Edgington-Mitchell, Laura, Porter, Christopher J. H., Halls, Michelle L., Canals, Meritxell, Veldhuis, Nicholas A., Poole, Daniel P., McLean, Peter, Hicks, Gareth A., Scheff, Nicole, Chen, Elyssa, Bhattacharya, Aditi, Schmidt, Brian L., Brierley, Stuart M., Vanner, Stephen J., Bunnett, Nigel W.
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Published in Proceedings of the National Academy of Sciences - PNAS (31.07.2018)
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Effects of Serotonin and Slow-Release 5-Hydroxytryptophan on Gastrointestinal Motility in a Mouse Model of Depression
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Published in Gastroenterology (New York, N.Y. 1943) (01.08.2019)
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TRPA1/NOX in the soma of trigeminal ganglion neurons mediates migraine-related pain of glyceryl trinitrate in mice
Marone, Ilaria Maddalena, De Logu, Francesco, Nassini, Romina, De Carvalho Goncalves, Muryel, Benemei, Silvia, Ferreira, Juliano, Jain, Piyush, Li Puma, Simone, Bunnett, Nigel W, Geppetti, Pierangelo, Materazzi, Serena
Published in Brain (London, England : 1878) (01.08.2018)
Published in Brain (London, England : 1878) (01.08.2018)
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The G protein-coupled receptor-transient receptor potential channel axis: molecular insights for targeting disorders of sensation and inflammation
Veldhuis, Nicholas A, Poole, Daniel P, Grace, Megan, McIntyre, Peter, Bunnett, Nigel W
Published in Pharmacological reviews (01.01.2015)
Published in Pharmacological reviews (01.01.2015)
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Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice
De Logu, Francesco, Nassini, Romina, Materazzi, Serena, Carvalho Gonçalves, Muryel, Nosi, Daniele, Rossi Degl’Innocenti, Duccio, Marone, Ilaria M., Ferreira, Juliano, Li Puma, Simone, Benemei, Silvia, Trevisan, Gabriela, Souza Monteiro de Araújo, Daniel, Patacchini, Riccardo, Bunnett, Nigel W., Geppetti, Pierangelo
Published in Nature communications (01.12.2017)
Published in Nature communications (01.12.2017)
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The Receptor TGR5 Mediates the Prokinetic Actions of Intestinal Bile Acids and Is Required for Normal Defecation in Mice
Alemi, Farzad, Poole, Daniel P, Chiu, Jonathan, Schoonjans, Kristina, Cattaruzza, Fiore, Grider, John R, Bunnett, Nigel W, Corvera, Carlos U
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2013)
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2013)
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Biased signaling of protease-activated receptors
Zhao, Peishen, Metcalf, Matthew, Bunnett, Nigel W
Published in Frontiers in endocrinology (Lausanne) (01.01.2014)
Published in Frontiers in endocrinology (Lausanne) (01.01.2014)
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Neutrophil Elastase Activates Protease-activated Receptor-2 (PAR2) and Transient Receptor Potential Vanilloid 4 (TRPV4) to Cause Inflammation and Pain
Zhao, Peishen, Lieu, TinaMarie, Barlow, Nicholas, Sostegni, Silvia, Haerteis, Silke, Korbmacher, Christoph, Liedtke, Wolfgang, Jimenez-Vargas, Nestor N., Vanner, Stephen J., Bunnett, Nigel W.
Published in The Journal of biological chemistry (29.05.2015)
Published in The Journal of biological chemistry (29.05.2015)
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Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice
De Logu, Francesco, Nassini, Romina, Hegron, Alan, Landini, Lorenzo, Jensen, Dane D., Latorre, Rocco, Ding, Julia, Marini, Matilde, Souza Monteiro de Araujo, Daniel, Ramírez-Garcia, Paulina, Whittaker, Michael, Retamal, Jeffri, Titiz, Mustafa, Innocenti, Alessandro, Davis, Thomas P., Veldhuis, Nicholas, Schmidt, Brian L., Bunnett, Nigel W., Geppetti, Pierangelo
Published in Nature communications (03.02.2022)
Published in Nature communications (03.02.2022)
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The TGR5 receptor mediates bile acid-induced itch and analgesia
Alemi, Farzad, Kwon, Edwin, Poole, Daniel P, Lieu, TinaMarie, Lyo, Victoria, Cattaruzza, Fiore, Cevikbas, Ferda, Steinhoff, Martin, Nassini, Romina, Materazzi, Serena, Guerrero-Alba, Raquel, Valdez-Morales, Eduardo, Cottrell, Graeme S, Schoonjans, Kristina, Geppetti, Pierangelo, Vanner, Stephen J, Bunnett, Nigel W, Corvera, Carlos U
Published in The Journal of clinical investigation (01.04.2013)
Published in The Journal of clinical investigation (01.04.2013)
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The Bile Acid Receptor TGR5 Activates the TRPA1 Channel to Induce Itch in Mice
Lieu, TinaMarie, Jayaweera, Gihan, Zhao, Peishen, Poole, Daniel P, Jensen, Dane, Grace, Megan, McIntyre, Peter, Bron, Romke, Wilson, Yvette M, Krappitz, Matteus, Haerteis, Silke, Korbmacher, Christoph, Steinhoff, Martin S, Nassini, Romina, Materazzi, Serena, Geppetti, Pierangelo, Corvera, Carlos U, Bunnett, Nigel W
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2014)
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2014)
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Neuronal Control of Skin Function: The Skin as a Neuroimmunoendocrine Organ
Roosterman, Dirk, Goerge, Tobias, Schneider, Stefan W, Bunnett, Nigel W, Steinhoff, Martin
Published in Physiological reviews (01.10.2006)
Published in Physiological reviews (01.10.2006)
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Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission
Yarwood, Rebecca E., Imlach, Wendy L., Lieu, TinaMarie, Veldhuis, Nicholas A., Jensen, Dane D., Herenbrink, Carmen Klein, Aurelio, Luigi, Cai, Zhijian, Christie, MacDonald J., Poole, Daniel P., Porter, Christopher J. H., McLean, Peter, Hicks, Gareth A., Geppetti, Pierangelo, Halls, Michelle L., Canals, Meritxell, Bunnett, Nigel W.
Published in Proceedings of the National Academy of Sciences - PNAS (14.11.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (14.11.2017)
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Contributions of bile acids to gastrointestinal physiology as receptor agonists and modifiers of ion channels
Keely, Stephen J, Urso, Andreacarola, Ilyaskin, Alexandr V, Korbmacher, Christoph, Bunnett, Nigel W, Poole, Daniel P, Carbone, Simona E
Published in American journal of physiology: Gastrointestinal and liver physiology (01.02.2022)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.02.2022)
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4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
Trevisani, Marcello, Siemens, Jan, Materazzi, Serena, Bautista, Diana M, Nassini, Romina, Campi, Barbara, Imamachi, Noritaka, Andrè, Eunice, Patacchini, Riccardo, Cottrell, Graeme S, Gatti, Raffaele, Basbaum, Allan I, Bunnett, Nigel W, Julius, David, Geppetti, Pierangelo
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2007)
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Protease-activated Receptor 2 (PAR2) Protein and Transient Receptor Potential Vanilloid 4 (TRPV4) Protein Coupling Is Required for Sustained Inflammatory Signaling
Poole, Daniel P., Amadesi, Silvia, Veldhuis, Nicholas A., Abogadie, Fe C., Lieu, TinaMarie, Darby, William, Liedtke, Wolfgang, Lew, Michael J., McIntyre, Peter, Bunnett, Nigel W.
Published in The Journal of biological chemistry (22.02.2013)
Published in The Journal of biological chemistry (22.02.2013)
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Role for protease activity in visceral pain in irritable bowel syndrome
Cenac, Nicolas, Andrews, Christopher N, Holzhausen, Marinella, Chapman, Kevin, Cottrell, Graeme, Andrade-Gordon, Patricia, Steinhoff, Martin, Barbara, Giovanni, Beck, Paul, Bunnett, Nigel W, Sharkey, Keith A, Ferraz, Jose Geraldo P, Shaffer, Eldon, Vergnolle, Nathalie
Published in The Journal of clinical investigation (01.03.2007)
Published in The Journal of clinical investigation (01.03.2007)
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