N-terminomics profiling of naïve and inflamed murine colon reveals proteolytic signatures of legumain
Ziegler, Alexander R, Anderson, Bethany M, Latorre, Rocco, McQuade, Rachel M, Dufour, Antoine, Schmidt, Brian L, Bunnett, Nigel W, Scott, Nichollas E, Edgington-Mitchell, Laura E
Published in Journal of cellular physiology (11.10.2024)
Published in Journal of cellular physiology (11.10.2024)
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PAR2 on oral cancer cells and nociceptors contributes to oral cancer pain that can be relieved by nanoparticle-encapsulated AZ3451
Bhansali, Divya, Tu, Nguyen H., Inoue, Kenji, Teng, Shavonne, Li, Tianyu, Tran, Hung D., Kim, Dong H., Dong, Jessy, Peach, Chloe J., Sokrat, Badr, Jensen, Dane D., Dolan, John C., Yamano, Seiichi, Robinson, Valeria Mezzano, Bunnett, Nigel W., Albertson, Donna G., Leong, Kam W., Schmidt, Brian L.
Published in Biomaterials (01.03.2025)
Published in Biomaterials (01.03.2025)
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Evolving acidic microenvironments during colitis provide selective analgesic targets for a pH-sensitive opioid
Degro, Claudius E, Jiménez-Vargas, Nestor Nivardo, Tsang, Quentin, Yu, Yang, Guzman-Rodriguez, Mabel, Alizadeh, Elahe, Hurlbut, David, Reed, David E, Lomax, Alan E, Stein, Christoph, Bunnett, Nigel W, Vanner, Stephen J
Published in Pain (Amsterdam) (01.11.2023)
Published in Pain (Amsterdam) (01.11.2023)
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Therapeutic antagonism of the neurokinin 1 receptor in endosomes provides sustained pain relief
Hegron, Alan, Peach, Chloe J, Tonello, Raquel, Seemann, Philipp, Teng, Shavonne, Latorre, Rocco, Huebner, Harald, Weikert, Dorothee, Rientjes, Jeanette, Veldhuis, Nicholas A, Poole, Daniel P, Jensen, Dane D, Thomsen, Alex R B, Schmidt, Brian L, Imlach, Wendy L, Gmeiner, Peter, Bunnett, Nigel W
Published in Proceedings of the National Academy of Sciences - PNAS (30.05.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (30.05.2023)
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Mice expressing fluorescent PAR2 reveal that endocytosis mediates colonic inflammation and pain
Latorre, Rocco, Hegron, Alan, Peach, Chloe J, Teng, Shavonne, Tonello, Raquel, Retamal, Jeffri S, Klein-Cloud, Rafael, Bok, Diana, Jensen, Dane D, Gottesman-Katz, Lena, Rientjes, Jeanette, Veldhuis, Nicholas A, Poole, Daniel P, Schmidt, Brian L, Pothoulakis, Charalabos H, Rankin, Carl, Xie, Ying, Koon, Wai, Bunnett, Nigel W
Published in Proceedings of the National Academy of Sciences - PNAS (08.02.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (08.02.2022)
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Sustained endosomal release of a neurokinin-1 receptor antagonist from nanostars provides long-lasting relief of chronic pain
Latorre, Rocco, Ramírez-Garcia, Paulina D., Hegron, Alan, Grace, James L., Retamal, Jeffri S., Shenoy, Priyank, Tran, Mai, Aurelio, Luigi, Flynn, Bernard, Poole, Daniel P., Klein-Cloud, Rafael, Jensen, Dane D., Davis, Thomas P., Schmidt, Brian L., Quinn, John F., Whittaker, Michael R., Veldhuis, Nicholas A., Bunnett, Nigel W.
Published in Biomaterials (01.06.2022)
Published in Biomaterials (01.06.2022)
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Agonists of proteinase‐activated receptor 1 induce plasma extravasation by a neurogenic mechanism
Garavilla, Lawrence de, Vergnolle, Nathalie, Young, Steven H, Ennes, Helena, Steinhoff, Martin, Ossovskaya, Valeria S, D'Andrea, Michael R, Mayer, Emeran A, Wallace, John L, Hollenberg, Morley D, Andrade‐Gordon, Patricia, Bunnett, Nigel W
Published in British journal of pharmacology (01.08.2001)
Published in British journal of pharmacology (01.08.2001)
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Antibodies: friend or foe?
Bron, Romke, Bunnett, Nigel W
Published in American journal of physiology: Gastrointestinal and liver physiology (01.11.2015)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.11.2015)
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Neural peptidase endothelin-converting enzyme 1 regulates endothelin 1-induced pruritus
Kido-Nakahara, Makiko, Buddenkotte, Jörg, Kempkes, Cordula, Ikoma, Akihiko, Cevikbas, Ferda, Akiyama, Tasuku, Nunes, Frank, Seeliger, Stephan, Hasdemir, Burcu, Mess, Christian, Buhl, Timo, Sulk, Mathias, Müller, Frank-Ulrich, Metze, Dieter, Bunnett, Nigel W, Bhargava, Aditi, Carstens, Earl, Furue, Masutaka, Steinhoff, Martin
Published in The Journal of clinical investigation (01.06.2014)
Published in The Journal of clinical investigation (01.06.2014)
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Cutaneous allergic contact dermatitis responses are diminished in mice deficient in neurokinin 1 receptors and augmented by neurokinin 2 receptor blockage
Scholzen, Thomas E, Steinhoff, Martin, Sindrilaru, Anca, Schwarz, Agatha, Bunnett, Nigel W, Luger, Thomas A, Armstrong, Cheryl A, Ansel, John C
Published in The FASEB journal (01.06.2004)
Published in The FASEB journal (01.06.2004)
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Bile acids inhibit cholinergic constriction in proximal and peripheral airways from humans and rodents
Urso, Andreacarola, D'Ovidio, Frank, Xu, Dingbang, Emala, Sr, Charles W, Bunnett, Nigel W, Perez-Zoghbi, Jose F
Published in American journal of physiology. Lung cellular and molecular physiology (01.02.2020)
Published in American journal of physiology. Lung cellular and molecular physiology (01.02.2020)
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Plasma membrane localization of the μ-opioid receptor controls spatiotemporal signaling
Halls, Michelle L, Yeatman, Holly R, Nowell, Cameron J, Thompson, Georgina L, Gondin, Arisbel Batista, Civciristov, Srgjan, Bunnett, Nigel W, Lambert, Nevin A, Poole, Daniel P, Canals, Meritxell
Published in Science signaling (09.02.2016)
Published in Science signaling (09.02.2016)
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Heterologous Regulation of Trafficking and Signaling of G Protein-Coupled Receptors: β-Arrestin-Dependent Interactions between Neurokinin Receptors
Schmidlin, Fabien, Déry, Olivier, Bunnett, Nigel W., Grady, Eileen F.
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.2002)
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Stress activates pronociceptive endogenous opioid signalling in DRG neurons during chronic colitis
Guerrero-Alba, Raquel, Valdez-Morales, Eduardo E, Jimenez-Vargas, Nestor N, Lopez-Lopez, Cintya, Jaramillo-Polanco, Josue, Okamoto, Takanobu, Nasser, Yasmin, Bunnett, Nigel W, Lomax, Alan E, Vanner, Stephen J
Published in Gut (01.12.2017)
Published in Gut (01.12.2017)
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Distribution and trafficking of the μ-opioid receptor in enteric neurons of the guinea pig
Lay, Joslyn, Carbone, Simona E, DiCello, Jesse J, Bunnett, Nigel W, Canals, Meritxell, Poole, Daniel P
Published in American journal of physiology: Gastrointestinal and liver physiology (01.08.2016)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.08.2016)
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Neurokinin 1 Receptor Internalization in Spinal Cord Slices Induced by Dorsal Root Stimulation Is Mediated by NMDA Receptors
Marvizon, Juan Carlos G, Martinez, Vicente, Grady, Eileen F, Bunnett, Nigel W, Mayer, Emeran A
Published in The Journal of neuroscience (01.11.1997)
Published in The Journal of neuroscience (01.11.1997)
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Protease-activated receptor 2 sensitizes TRPV1 by protein kinase C epsilon - and A-dependent mechanisms in rats and mice
Amadesi, Silvia, Cottrell, Graeme S, Divino, Lorna, Chapman, Kevin, Grady, Eileen F, Bautista, Francisco, Karanjia, Rustum, Barajas-Lopez, Carlos, Vanner, Stephen, Vergnolle, Nathalie, Bunnett, Nigel W
Published in The Journal of physiology (01.09.2006)
Published in The Journal of physiology (01.09.2006)
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Application of a chemical probe to detect neutrophil elastase activation during inflammatory bowel disease
Anderson, Bethany M., Poole, Daniel P., Aurelio, Luigi, Ng, Garrett Z., Fleischmann, Markus, Kasperkiewicz, Paulina, Morissette, Celine, Drag, Marcin, van Driel, Ian R., Schmidt, Brian L., Vanner, Stephen J., Bunnett, Nigel W., Edgington-Mitchell, Laura E.
Published in Scientific reports (16.09.2019)
Published in Scientific reports (16.09.2019)
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The Bile Acid Receptor TGR5 Does Not Interact with β-Arrestins or Traffic to Endosomes but Transmits Sustained Signals from Plasma Membrane Rafts
Jensen, Dane D., Godfrey, Cody B., Niklas, Christian, Canals, Meritxell, Kocan, Martina, Poole, Daniel P., Murphy, Jane E., Alemi, Farzad, Cottrell, Graeme S., Korbmacher, Christoph, Lambert, Nevin A., Bunnett, Nigel W., Corvera, Carlos U.
Published in The Journal of biological chemistry (09.08.2013)
Published in The Journal of biological chemistry (09.08.2013)
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