The predominant PAR4 variant in individuals of African ancestry worsens murine and human stroke outcomes
Denorme, Frederik, Armstrong, Nicole D, Stoller, Michelle L, Portier, Irina, Tugolukova, Emilia A, Tanner, Rikki M, Montenont, Emilie, Bhatlekar, Seema, Cody, Mark, Rustad, John L, Ajanel, Abigail, Tolley, Neal D, Murray, Darian C, Boyle, Julie L, Nieman, Marvin T, McKenzie, Steven E, Yost, Christian Con, Lange, Leslie A, Cushman, Mary, Irvin, Marguerite R, Bray, Paul F, Campbell, Robert A
Published in The Journal of clinical investigation (15.09.2023)
Published in The Journal of clinical investigation (15.09.2023)
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Journal Article
Variant level heritability estimates of type 2 diabetes in African Americans
Armstrong, Nicole D., Patki, Amit, Srinivasasainagendra, Vinodh, Ge, Tian, Lange, Leslie A., Kottyan, Leah, Namjou, Bahram, Shah, Amy S., Rasmussen-Torvik, Laura J., Jarvik, Gail P., Meigs, James B., Karlson, Elizabeth W., Limdi, Nita A., Irvin, Marguerite R., Tiwari, Hemant K.
Published in Scientific reports (18.06.2024)
Published in Scientific reports (18.06.2024)
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Journal Article
Telomere shortening and the transition to family caregiving in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study
Armstrong, Nicole D, Irvin, Marguerite R, Haley, William E, Blinka, Marcela D, Kamin Mukaz, Debora, Patki, Amit, Rutherford Siegel, Sue, Shalev, Idan, Durda, Peter, Mathias, Rasika A, Walston, Jeremy D, Roth, David L
Published in PloS one (03.06.2022)
Published in PloS one (03.06.2022)
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Journal Article
The Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet and Metabolites in Chronic Kidney Disease
Couch, Catharine A, Ament, Zsuzsanna, Patki, Amit, Kijpaisalratana, Naruchorn, Bhave, Varun, Jones, Alana C, Armstrong, Nicole D, Cheung, Katharine L, Kimberly, W Taylor, Tiwari, Hemant K, Irvin, Marguerite Ryan
Published in Nutrients (01.08.2024)
Published in Nutrients (01.08.2024)
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Journal Article
Sex-Associated Metabolites and Incident Stroke, Incident Coronary Heart Disease, Hypertension, and Chronic Kidney Disease in the REGARDS Cohort
Couch, Catharine A, Ament, Zsuzsanna, Patki, Amit, Kijpaisalratana, Naruchorn, Bhave, Varun, Jones, Alana C, Armstrong, Nicole D, Cushman, Mary, Kimberly, W Taylor, Irvin, M Ryan
Published in Journal of the American Heart Association (07.05.2024)
Published in Journal of the American Heart Association (07.05.2024)
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Journal Article
Corin Missense Variants, Blood Pressure, and Hypertension in 11 322 Black Individuals: Insights From REGARDS and the Jackson Heart Study
Parcha, Vibhu, Irvin, Marguerite R, Lange, Leslie A, Armstrong, Nicole D, Pampana, Akhil, Meyer, Mariah, Judd, Suzanne E, Arora, Garima, Arora, Pankaj
Published in Journal of the American Heart Association (21.06.2022)
Published in Journal of the American Heart Association (21.06.2022)
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Journal Article
Genetic Contributors of Incident Stroke in 10,700 African Americans With Hypertension: A Meta-Analysis From the Genetics of Hypertension Associated Treatments and Reasons for Geographic and Racial Differences in Stroke Studies
Armstrong, Nicole D, Srinivasasainagendra, Vinodh, Patki, Amit, Tanner, Rikki M, Hidalgo, Bertha A, Tiwari, Hemant K, Limdi, Nita A, Lange, Ethan M, Lange, Leslie A, Arnett, Donna K, Irvin, Marguerite R
Published in Frontiers in genetics (21.12.2021)
Published in Frontiers in genetics (21.12.2021)
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Journal Article
Genomics of Postprandial Lipidomics in the Genetics of Lipid-Lowering Drugs and Diet Network Study
Irvin, Marguerite R, Montasser, May E, Kind, Tobias, Fan, Sili, Barupal, Dinesh K, Patki, Amit, Tanner, Rikki M, Armstrong, Nicole D, Ryan, Kathleen A, Claas, Steven A, O'Connell, Jeffrey R, Tiwari, Hemant K, Arnett, Donna K
Published in Nutrients (10.11.2021)
Published in Nutrients (10.11.2021)
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Journal Article
SMOC2 gene interacts with APOL1 in the development of end-stage kidney disease: A genome-wide association study
Chaudhary, Ninad S, Armstrong, Nicole D, Hidalgo, Bertha A, Gutiérrez, Orlando M, Hellwege, Jacklyn N, Limdi, Nita A, Reynolds, Richard J, Judd, Suzanne E, Nadkarni, Girish N, Lange, Leslie, Winkler, Cheryl A, Kopp, Jeffrey B, Arnett, Donna K, Tiwari, Hemant K, Irvin, Marguerite R
Published in Frontiers in medicine (28.09.2022)
Published in Frontiers in medicine (28.09.2022)
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Journal Article
Association of Transthyretin Val122Ile Variant With Incident Heart Failure Among Black Individuals
Parcha, Vibhu, Malla, Gargya, Irvin, Marguerite R, Armstrong, Nicole D, Judd, Suzanne E, Lange, Leslie A, Maurer, Mathew S, Levitan, Emily B, Goyal, Parag, Arora, Garima, Arora, Pankaj
Published in JAMA : the journal of the American Medical Association (12.04.2022)
Published in JAMA : the journal of the American Medical Association (12.04.2022)
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Journal Article
Polygenic Risk for Type 2 Diabetes in African Americans
Irvin, Marguerite R, Ge, Tian, Patki, Amit, Srinivasasainagendra, Vinodh, Armstrong, Nicole D, Davis, Brittney, Jones, Alana C, Perez, Emma, Stalbow, Lauren, Lebo, Matthew, Kenny, Eimear, Loos, Ruth J F, Ng, Maggie C Y, Smoller, Jordan W, Meigs, James B, Lange, Leslie A, Karlson, Elizabeth W, Limdi, Nita A, Tiwari, Hemant K
Published in Diabetes (New York, N.Y.) (01.06.2024)
Published in Diabetes (New York, N.Y.) (01.06.2024)
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Journal Article
Single-Ancestry versus Multi-Ancestry Polygenic Risk Scores for CKD in Black American Populations
Jones, Alana C., Patki, Amit, Srinivasasainagendra, Vinodh, Tiwari, Hemant K., Armstrong, Nicole D., Chaudhary, Ninad S., Limdi, Nita A., Hidalgo, Bertha A., Davis, Brittney, Cimino, James J., Khan, Atlas, Kiryluk, Krzysztof, Lange, Leslie A., Lange, Ethan M., Arnett, Donna K., Young, Bessie A., Diamantidis, Clarissa J., Franceschini, Nora, Wassertheil-Smoller, Sylvia, Rich, Stephen S., Rotter, Jerome I., Mychaleckyj, Josyf C., Kramer, Holly J., Chen, Yii-Der I., Psaty, Bruce M., Brody, Jennifer A., de Boer, Ian H., Bansal, Nisha, Bis, Joshua C., Irvin, Marguerite R.
Published in Journal of the American Society of Nephrology (01.11.2024)
Published in Journal of the American Society of Nephrology (01.11.2024)
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Journal Article
Single- versus Multi-Ancestry Polygenic Risk Scores for CKD in Black Americans
Jones, Alana C, Patki, Amit, Srinivasasainagendra, Vinodh, Tiwari, Hemant K, Armstrong, Nicole D, Chaudhary, Ninad S, Limdi, Nita A, Hidalgo, Bertha A, Davis, Brittney, Cimino, James J, Khan, Atlas, Kiryluk, Krzysztof, Lange, Leslie A, Lange, Ethan M, Arnett, Donna K, Young, Bessie A, Diamantidis, Clarissa J, Franceschini, Nora, Wassertheil-Smoller, Sylvia, Rich, Stephen S, Rotter, Jerome I, Mychaleckyj, Josyf C, Kramer, Holly J, Chen, Yii-Der I, Psaty, Bruce M, Brody, Jennifer A, de Boer, Ian H, Bansal, Nisha, Bis, Joshua C, Irvin, Marguerite R
Published in Journal of the American Society of Nephrology (29.07.2024)
Published in Journal of the American Society of Nephrology (29.07.2024)
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Journal Article
Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations
Ge, Tian, Irvin, Marguerite R, Patki, Amit, Srinivasasainagendra, Vinodh, Lin, Yen-Feng, Tiwari, Hemant K, Armstrong, Nicole D, Benoit, Barbara, Chen, Chia-Yen, Choi, Karmel W, Cimino, James J, Davis, Brittney H, Dikilitas, Ozan, Etheridge, Bethany, Feng, Yen-Chen Anne, Gainer, Vivian, Huang, Hailiang, Jarvik, Gail P, Kachulis, Christopher, Kenny, Eimear E, Khan, Atlas, Kiryluk, Krzysztof, Kottyan, Leah, Kullo, Iftikhar J, Lange, Christoph, Lennon, Niall, Leong, Aaron, Malolepsza, Edyta, Miles, Ayme D, Murphy, Shawn, Namjou, Bahram, Narayan, Renuka, O'Connor, Mark J, Pacheco, Jennifer A, Perez, Emma, Rasmussen-Torvik, Laura J, Rosenthal, Elisabeth A, Schaid, Daniel, Stamou, Maria, Udler, Miriam S, Wei, Wei-Qi, Weiss, Scott T, Ng, Maggie C Y, Smoller, Jordan W, Lebo, Matthew S, Meigs, James B, Limdi, Nita A, Karlson, Elizabeth W
Published in Genome medicine (29.06.2022)
Published in Genome medicine (29.06.2022)
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Journal Article
Adverse Cardiovascular Outcomes and Antihypertensive Treatment: A Genome-Wide Interaction Meta-Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies
McDonough, Caitrin W, Warren, Helen R, Jack, John R, Motsinger-Reif, Alison A, Armstrong, Nicole D, Bis, Joshua C, House, John S, Singh, Sonal, El Rouby, Nihal M, Gong, Yan, Mychaleckyj, Joesyf C, Rotroff, Daniel M, Benavente, Oscar R, Caulfield, Mark J, Doria, Alessandrio, Pepine, Carl J, Psaty, Bruce M, Glorioso, Valeria, Glorioso, Nicola, Hiltunen, Timo P, Kontula, Kimmo K, Arnett, Donna K, Buse, John B, Irvin, Marguerite R, Johnson, Julie A, Munroe, Patricia B, Wagner, Michael J, Cooper-DeHoff, Rhonda M
Published in Clinical pharmacology and therapeutics (01.09.2021)
Published in Clinical pharmacology and therapeutics (01.09.2021)
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Journal Article
Circulating Metabolites Associated with Albuminuria in a Hispanic/Latino Population
Reynolds, Kaylia M, Lin, Bridget M, Armstrong, Nicole D, Ottosson, Filip, Zhang, Ying, Williams, Ashley S, Yu, Bing, Boerwinkle, Eric, Thygarajan, Bharat, Daviglus, Martha L, Muoio, Deborah, Qi, Qibin, Kaplan, Robert, Melander, Olle, Lash, James P, Cai, Jianwen, Irvin, Marguerite R, Newgard, Christopher B, Sofer, Tamar, Franceschini, Nora
Published in Clinical journal of the American Society of Nephrology (01.02.2023)
Published in Clinical journal of the American Society of Nephrology (01.02.2023)
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Journal Article
Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study
Downie, Carolina G., Dimos, Sofia F., Bien, Stephanie A., Hu, Yao, Darst, Burcu F., Polfus, Linda M., Wang, Yujie, Wojcik, Genevieve L., Tao, Ran, Raffield, Laura M., Armstrong, Nicole D., Polikowsky, Hannah G., Below, Jennifer E., Correa, Adolfo, Irvin, Marguerite R., Rasmussen-Torvik, Laura J. F., Carlson, Christopher S., Phillips, Lawrence S., Liu, Simin, Pankow, James S., Rich, Stephen S., Rotter, Jerome I., Buyske, Steven, Matise, Tara C., North, Kari E., Avery, Christy L., Haiman, Christopher A., Loos, Ruth J. F., Kooperberg, Charles, Graff, Mariaelisa, Highland, Heather M.
Published in Diabetologia (01.03.2022)
Published in Diabetologia (01.03.2022)
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Journal Article
A methylation risk score for chronic kidney disease: a HyperGEN study
Jones, Alana C., Patki, Amit, Srinivasasainagendra, Vinodh, Hidalgo, Bertha A., Tiwari, Hemant K., Limdi, Nita A., Armstrong, Nicole D., Chaudhary, Ninad S., Minniefield, Bré, Absher, Devin, Arnett, Donna K., Lange, Leslie A., Lange, Ethan M., Young, Bessie A., Diamantidis, Clarissa J., Rich, Stephen S., Mychaleckyj, Josyf C., Rotter, Jerome I., Taylor, Kent D., Kramer, Holly J., Tracy, Russell P., Durda, Peter, Kasela, Silva, Lappalinen, Tuuli, Liu, Yongmei, Johnson, W. Craig, Van Den Berg, David J., Franceschini, Nora, Liu, Simin, Mouton, Charles P., Bhatti, Parveen, Horvath, Steve, Whitsel, Eric A., Irvin, Marguerite R.
Published in Scientific reports (01.08.2024)
Published in Scientific reports (01.08.2024)
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Journal Article
Higher Serum Urate Levels Are Associated With an Increased Risk for Sudden Cardiac Death
Colantonio, Lisandro D, Reynolds, Richard J, Merriman, Tony R, Gaffo, Angelo, Singh, Jasvinder A, Plante, Timothy B, Chaudhary, Ninad S, Armstrong, Nicole D, Soliman, Elsayed Z, Curtis, Jeffrey R, Bridges, Jr, S Louis, Lang, Leslie, Howard, George, Safford, Monika M, Saag, Kenneth G, Muntner, Paul, Irvin, Marguerite Ryan
Published in Journal of rheumatology (01.11.2021)
Published in Journal of rheumatology (01.11.2021)
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Journal Article
Utility of a Systolic Blood Pressure Polygenic Risk Score With Chlorthalidone Response
Armstrong, Nicole D, Srinivasasainagendra, Vinodh, Patki, Amit, Jones, Alana C, Parcha, Vibhu, Pampana, Akhil, Broeckel, Ulrich, Lange, Leslie A, Arora, Pankaj, Limdi, Nita A, Tiwari, Hemant K, Irvin, Marguerite R
Published in JAMA cardiology (23.10.2024)
Published in JAMA cardiology (23.10.2024)
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