Evolution of NETosis markers and DAMPs have prognostic value in critically ill COVID-19 patients
Huckriede, Joram, Anderberg, Sara Bülow, Morales, Albert, de Vries, Femke, Hultström, Michael, Bergqvist, Anders, Ortiz-Pérez, José T., Sels, Jan Willem, Wichapong, Kanin, Lipcsey, Miklos, van de Poll, Marcel, Larsson, Anders, Luther, Tomas, Reutelingsperger, Chris, de Frutos, Pablo Garcia, Frithiof, Robert, Nicolaes, Gerry A. F.
Published in Scientific reports (03.08.2021)
Published in Scientific reports (03.08.2021)
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M6229 Protects against Extracellular-Histone-Induced Liver Injury, Kidney Dysfunction, and Mortality in a Rat Model of Acute Hyperinflammation
Reutelingsperger, Chris P M, Gijbels, Marion J, Spronk, Henri, Van Oerle, Rene, Schrijver, Roy, Ekhart, Peter, de Kimpe, Sjef, Nicolaes, Gerry A F
Published in International journal of molecular sciences (01.02.2024)
Published in International journal of molecular sciences (01.02.2024)
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Discovery of Small Molecule CD40–TRAF6 Inhibitors
Zarzycka, Barbara, Seijkens, Tom, Nabuurs, Sander B, Ritschel, Tina, Grommes, Jochen, Soehnlein, Oliver, Schrijver, Roy, van Tiel, Claudia M, Hackeng, Tilman M, Weber, Christian, Giehler, Fabian, Kieser, Arnd, Lutgens, Esther, Vriend, Gert, Nicolaes, Gerry A. F
Published in Journal of chemical information and modeling (23.02.2015)
Published in Journal of chemical information and modeling (23.02.2015)
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Extracellular histone release by renal cells after warm and cold ischemic kidney injury: Studies in an ex-vivo porcine kidney perfusion model
van Smaalen, Tim C, Beurskens, Danielle M H, Kox, Jasper J H F M, Polonia, Rasheendra, Vos, Rein, Duimel, Hans, van de Wetering, Willine J, López-Iglesias, Carmen, Reutelingsperger, Chris P, Ernest van Heurn, L W, Peutz-Kootstra, Carine J, Nicolaes, Gerry A F
Published in PloS one (20.01.2023)
Published in PloS one (20.01.2023)
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Riboflavin-responsive oxidative phosphorylation complex I deficiency caused by defective ACAD9: new function for an old gene
GERARDS, Mike, VAN DEN BOSCH, Bianca J. C, PROKISCH, Holger, RÖTIG, Agnès, DE COO, Irenaeus F. M, SMELTS, Hubert J. M, DANHAUSER, Katharina, SERRE, Valérie, VAN WEEGHEL, Michel, WANDERS, Ronald J. A, NICOLAES, Gerry A. F, SLUITER, Wim, SCHOONDERWOERD, Kees, SCHOLTE, Hans R
Published in Brain (London, England : 1878) (2011)
Published in Brain (London, England : 1878) (2011)
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Effects of exogenous recombinant APC in mouse models of ischemia reperfusion injury and of atherosclerosis
Wildhagen, Karin C A A, Schrijver, Roy, Beckers, Linda, ten Cate, Hugo, Reutelingsperger, Chris P M, Lutgens, Esther, Nicolaes, Gerry A F
Published in PloS one (17.07.2014)
Published in PloS one (17.07.2014)
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Journal Article
Nonanticoagulant heparin prevents histone-mediated cytotoxicity in vitro and improves survival in sepsis
Wildhagen, Karin C.A.A., García de Frutos, Pablo, Reutelingsperger, Chris P., Schrijver, Roy, Aresté, Cristina, Ortega-Gómez, Almudena, Deckers, Niko M., Hemker, H. Coenraad, Soehnlein, Oliver, Nicolaes, Gerry A.F.
Published in Blood (13.02.2014)
Published in Blood (13.02.2014)
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Journal Article
Decreased endothelial glycocalyx thickness is an early predictor of mortality in sepsis
Beurskens, Daniëlle MH, Bol, Martine E, Delhaas, Tammo, van de Poll, Marcel CG, Reutelingsperger, Chris PM, Nicolaes, Gerry AF, Sels, Jan-Willem EM
Published in Anaesthesia and intensive care (01.05.2020)
Published in Anaesthesia and intensive care (01.05.2020)
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Journal Article
Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance
Braza, Mounia S., van Leent, Mandy M.T., Lameijer, Marnix, Sanchez-Gaytan, Brenda L., Arts, Rob J.W., Pérez-Medina, Carlos, Conde, Patricia, Garcia, Mercedes R., Gonzalez-Perez, Maria, Brahmachary, Manisha, Fay, Francois, Kluza, Ewelina, Kossatz, Susanne, Dress, Regine J., Salem, Fadi, Rialdi, Alexander, Reiner, Thomas, Boros, Peter, Strijkers, Gustav J., Calcagno, Claudia C., Ginhoux, Florent, Marazzi, Ivan, Lutgens, Esther, Nicolaes, Gerry A.F., Weber, Christian, Swirski, Filip K., Nahrendorf, Matthias, Fisher, Edward A., Duivenvoorden, Raphaël, Fayad, Zahi A., Netea, Mihai G., Mulder, Willem J.M., Ochando, Jordi
Published in Immunity (Cambridge, Mass.) (20.11.2018)
Published in Immunity (Cambridge, Mass.) (20.11.2018)
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Inhibition of Neutral Sphingomyelinase 2 by Novel Small Molecule Inhibitors Results in Decreased Release of Extracellular Vesicles by Vascular Smooth Muscle Cells and Attenuated Calcification
Pavlic, Angelina, Poelman, Hessel, Wasilewski, Grzegorz, Wichapong, Kanin, Lux, Petra, Maassen, Cecile, Lutgens, Esther, Schurgers, Leon J, Reutelingsperger, Chris P, Nicolaes, Gerry A F
Published in International journal of molecular sciences (19.01.2023)
Published in International journal of molecular sciences (19.01.2023)
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Journal Article
Design of Protein-Membrane Interaction Inhibitors by Virtual Ligand Screening, Proof of Concept with the C2 Domain of Factor V
Segers, Kenneth, Sperandio, Olivier, Sack, Markus, Fischer, Rainer, Miteva, Maria A., Rosing, Jan, Nicolaes, Gerry A. F., Villoutreix, Bruno O.
Published in Proceedings of the National Academy of Sciences - PNAS (31.07.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (31.07.2007)
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Structure-Based Design of Peptidic Inhibitors of the Interaction between CC Chemokine Ligand 5 (CCL5) and Human Neutrophil Peptides 1 (HNP1)
Wichapong, Kanin, Alard, Jean-Eric, Ortega-Gomez, Almudena, Weber, Christian, Hackeng, Tilman M, Soehnlein, Oliver, Nicolaes, Gerry A. F
Published in Journal of medicinal chemistry (12.05.2016)
Published in Journal of medicinal chemistry (12.05.2016)
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Journal Article
Histone H3 Cleavage in Severe COVID-19 ICU Patients
Huckriede, Joram, de Vries, Femke, Hultström, Michael, Wichapong, Kanin, Reutelingsperger, Chris, Lipcsey, Miklos, Garcia de Frutos, Pablo, Frithiof, Robert, Nicolaes, Gerry A. F.
Published in Frontiers in cellular and infection microbiology (10.09.2021)
Published in Frontiers in cellular and infection microbiology (10.09.2021)
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N-glycan–mediated shielding of ADAMTS13 prevents binding of pathogenic autoantibodies in immune-mediated TTP
Ercig, Bogac, Graça, Nuno A.G., Kangro, Kadri, Arfman, Tom, Wichapong, Kanin, Hrdinová, Johana, Kaijen, Paul, van Alphen, Floris P.J., van den Biggelaar, Maartje, Vanhoorelbeke, Karen, Veyradier, Agnès, Coppo, Paul, Reutelingsperger, Chris, Nicolaes, Gerry A.F., Männik, Andres, Voorberg, Jan
Published in Blood (13.05.2021)
Published in Blood (13.05.2021)
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Journal Article
Coagulation factor V and thrombophilia: background and mechanisms
Segers, Kenneth, Dahlbäck, Björn, Nicolaes, Gerry A F
Published in Thrombosis and haemostasis (01.09.2007)
Published in Thrombosis and haemostasis (01.09.2007)
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Factor Xa Activation of Factor V Is of Paramount Importance in Initiating the Coagulation System: Lessons From a Tick Salivary Protein
Schuijt, Tim J, Bakhtiari, Kamran, Daffre, Sirlei, DePonte, Kathleen, Wielders, Simone J.H, Marquart, J Arnoud, Hovius, Joppe W, van der Poll, Tom, Fikrig, Erol, Bunce, Matthew W, Camire, Rodney M, Nicolaes, Gerry A.F, Meijers, Joost C.M, van ‘t Veer, Cornelis
Published in Circulation (New York, N.Y.) (16.07.2013)
Published in Circulation (New York, N.Y.) (16.07.2013)
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Acetaminophen Overdose as a Potential Risk Factor for Parkinson's Disease
Bohler, Sacha, Liu, Xiaosong, Krauskopf, Julian, Caiment, Florian, Aubrecht, Jiri, Nicolaes, Gerry A. F., Kleinjans, Jos C. S., Briedé, Jacco J.
Published in Clinical and translational science (01.11.2019)
Published in Clinical and translational science (01.11.2019)
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Structure-Based Cyclic Glycoprotein Ibα-Derived Peptides Interfering with von Willebrand Factor-Binding, Affecting Platelet Aggregation under Shear
Hrdinova, Johana, Fernández, Delia I, Ercig, Bogac, Tullemans, Bibian M E, Suylen, Dennis P L, Agten, Stijn M, Jurk, Kerstin, Hackeng, Tilman M, Vanhoorelbeke, Karen, Voorberg, Jan, Reutelingsperger, Chris P M, Wichapong, Kanin, Heemskerk, Johan W M, Nicolaes, Gerry A F
Published in International journal of molecular sciences (12.02.2022)
Published in International journal of molecular sciences (12.02.2022)
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Journal Article
Role of Vitamin K-Dependent Factors Protein S and GAS6 and TAM Receptors in SARS-CoV-2 Infection and COVID-19-Associated Immunothrombosis
Tutusaus, Anna, Marí, Montserrat, Ortiz-Pérez, José T, Nicolaes, Gerry A F, Morales, Albert, García de Frutos, Pablo
Published in Cells (Basel, Switzerland) (28.09.2020)
Published in Cells (Basel, Switzerland) (28.09.2020)
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