Road Map for Development of Stem Cell-Based Alternative Test Methods
Sachinidis, Agapios, Albrecht, Wiebke, Nell, Patrick, Cherianidou, Anna, Hewitt, Nicola J., Edlund, Karolina, Hengstler, Jan G.
Published in Trends in molecular medicine (01.06.2019)
Published in Trends in molecular medicine (01.06.2019)
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Journal Article
A 10-step framework for use of read-across (RAX) in next generation risk assessment (NGRA) for cosmetics safety assessment
Alexander-White, Camilla, Bury, Dagmar, Cronin, Mark, Dent, Matthew, Hack, Eric, Hewitt, Nicola J., Kenna, Gerry, Naciff, Jorge, Ouedraogo, Gladys, Schepky, Andreas, Mahony, Catherine, Europe, Cosmetics
Published in Regulatory toxicology and pharmacology (01.03.2022)
Published in Regulatory toxicology and pharmacology (01.03.2022)
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Journal Article
ADME characterization and PBK model development of 3 highly protein-bound UV filters through topical application
Li, Hequn, Bunglawala, Fazila, Hewitt, Nicola J, Pendlington, Ruth, Cubberley, Richard, Nicol, Beate, Spriggs, Sandrine, Baltazar, Maria, Cable, Sophie, Dent, Matthew
Published in Toxicological sciences (30.10.2023)
Published in Toxicological sciences (30.10.2023)
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Journal Article
Read-across and new approach methodologies applied in a 10-step framework for cosmetics safety assessment – A case study with parabens
Ouedraogo, Gladys, Alexander-White, Camilla, Bury, Dagmar, Clewell, Harvey J., Cronin, Mark, Cull, Tom, Dent, Matthew, Desprez, Bertrand, Detroyer, Ann, Ellison, Corie, Giammanco, Stefania, Hack, Eric, Hewitt, Nicola J., Kenna, Gerry, Klaric, Martina, Kreiling, Reinhard, Lester, Cathy, Mahony, Catherine, Mombelli, Enrico, Naciff, Jorge, O'Brien, John, Schepky, Andreas, Tozer, Sarah, van der Burg, Bart, van Vugt-Lussenburg, Barbara, Stuard, Sharon, Cosmetics Europe
Published in Regulatory toxicology and pharmacology (01.07.2022)
Published in Regulatory toxicology and pharmacology (01.07.2022)
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Journal Article
Ambient air concentrations of plant protection products: Data collection for the combined air concentration database and associated risk assessment
Vinck, Anne-Kim, Felkers, Edgars, Urtizberea, Michel, Hewitt, Nicola J., Bürling, Kathrin, Morriss, Alistair
Published in Regulatory toxicology and pharmacology (01.05.2024)
Published in Regulatory toxicology and pharmacology (01.05.2024)
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Journal Article
Safety assessment for nail cosmetics: Framework for the estimation of systemic exposure through the nail plate
Yin, Xuejun J., Hewitt, Nicola J., Erler, Steffen, Bryson, Paul, Blömeke, Brunhilde, Gaspari, Anthony A., Goebel, Carsten
Published in Regulatory toxicology and pharmacology (01.03.2024)
Published in Regulatory toxicology and pharmacology (01.03.2024)
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Journal Article
Measured air concentrations of pesticides for the estimation of exposure to vapour in European risk assessments
Felkers, Edgars, Kluxen, Felix M., Adham, Sarah, Vinck, Anne-Kim, Hewitt, Nicola J., Morgan, Neil
Published in Regulatory toxicology and pharmacology (01.12.2022)
Published in Regulatory toxicology and pharmacology (01.12.2022)
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Journal Article
Demonstration of the first‐pass metabolism in the skin of the hair dye, 4‐amino‐2‐hydroxytoluene, using the Chip2 skin–liver microphysiological model
Tao, Thi Phuong, Brandmair, Katrin, Gerlach, Silke, Przibilla, Julia, Géniès, Camille, Jacques‐Jamin, Carine, Schepky, Andreas, Marx, Uwe, Hewitt, Nicola J., Maschmeyer, Ilka, Kühnl, Jochen
Published in Journal of applied toxicology (01.10.2021)
Published in Journal of applied toxicology (01.10.2021)
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Journal Article
Characterization of application scenario-dependent pharmacokinetics and pharmacodynamic properties of permethrin and hyperforin in a dynamic skin and liver multi-organ-chip model
Kühnl, Jochen, Tao, Thi Phuong, Brandmair, Katrin, Gerlach, Silke, Rings, Thamée, Müller-Vieira, Ursula, Przibilla, Julia, Genies, Camille, Jaques-Jamin, Carine, Schepky, Andreas, Marx, Uwe, Hewitt, Nicola J., Maschmeyer, Ilka
Published in Toxicology (Amsterdam) (30.01.2021)
Published in Toxicology (Amsterdam) (30.01.2021)
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Journal Article
Letter to the editor from the European Crop Protection Association (ECPA) Occupational and Bystander Exposure Expert Group (OBEEG) regarding a critical review of the role of Personal Protective Equipment (PPE) in agriculture
Morgan, Neil, McEuen, Steven, Hewitt, Nicola J., Durand-Réville, Julien
Published in Safety science (01.11.2020)
Published in Safety science (01.11.2020)
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Journal Article
Partition coefficient and diffusion coefficient determinations of 50 compounds in human intact skin, isolated skin layers and isolated stratum corneum lipids
Ellison, Corie A., Tankersley, Kevin O., Obringer, Cindy M., Carr, Greg J., Manwaring, John, Rothe, Helga, Duplan, Hélène, Géniès, Camille, Grégoire, Sébastien, Hewitt, Nicola J., Jamin, Carine Jacques, Klaric, Martina, Lange, Daniela, Rolaki, Alexandra, Schepky, Andreas
Published in Toxicology in vitro (01.12.2020)
Published in Toxicology in vitro (01.12.2020)
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Journal Article
Characterization of the in vitro penetration and first-pass metabolism of genistein and daidzein using human and pig skin explants and Phenion full-thickness skin models
Géniès, Camille, Jeanjean, Corinne, Najjar, Abdulkarim, Schepky, Andreas, Lange, Daniela, Kühnl, Jochen, Fabian, Eric, Zifle, Anne, Duplan, Hélène, Hewitt, NIcola J, Jacques, Carine
Published in Journal of applied toxicology (27.08.2024)
Published in Journal of applied toxicology (27.08.2024)
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Journal Article
Measurement of the penetration of 56 cosmetic relevant chemicals into and through human skin using a standardized protocol
Hewitt, Nicola J., Grégoire, Sébastien, Cubberley, Richard, Duplan, Hélène, Eilstein, Joan, Ellison, Corie, Lester, Cathy, Fabian, Eric, Fernandez, Julien, Géniès, Camille, Jacques‐Jamin, Carine, Klaric, Martina, Rothe, Helga, Sorrell, Ian, Lange, Daniela, Schepky, Andreas
Published in Journal of applied toxicology (01.03.2020)
Published in Journal of applied toxicology (01.03.2020)
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Journal Article
Use of human in vitro skin models for accurate and ethical risk assessment: metabolic considerations
Hewitt, Nicola J, Edwards, Robert J, Fritsche, Ellen, Goebel, Carsten, Aeby, Pierre, Scheel, Julia, Reisinger, Kerstin, Ouédraogo, Gladys, Duche, Daniel, Eilstein, Joan, Latil, Alain, Kenny, Julia, Moore, Claire, Kuehnl, Jochen, Barroso, Joao, Fautz, Rolf, Pfuhler, Stefan
Published in Toxicological sciences (01.06.2013)
Published in Toxicological sciences (01.06.2013)
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Journal Article
Application of a skin and liver Chip2 microphysiological model to investigate the route‐dependent toxicokinetics and toxicodynamics of consumer‐relevant doses of genistein
Tao, Thi‐Phuong, Brandmair, Katrin, Gerlach, Silke, Przibilla, Julia, Schepky, Andreas, Marx, Uwe, Hewitt, Nicola J., Maschmeyer, Ilka, Kühnl, Jochen
Published in Journal of applied toxicology (01.02.2024)
Published in Journal of applied toxicology (01.02.2024)
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Journal Article
Effect of vehicle on the in vitro penetration and metabolism of genistein and daidzein in ex vivo skin explants and the Phenion full-thickness skin model
Géniès, Camille, Jeanjean, Corinne, Najjar, Abdulkarim, Schepky, Andreas, Lange, Daniela, Kühnl, Jochen, Fabian, Eric, Zifle, Anne, Duplan, Helene, Hewitt, Nicola J, Jacques, Carine
Published in Journal of applied toxicology (27.08.2024)
Published in Journal of applied toxicology (27.08.2024)
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Journal Article