Validation of PAS Kinase, a Regulator of Hepatic Fatty Acid and Triglyceride Synthesis, as a Therapeutic Target for Nonalcoholic Steatohepatitis
Swiatek, Wojciech, Parnell, K. Mark, Nickols, G. Allen, Scharschmidt, Bruce F., Rutter, Jared
Published in Hepatology communications (01.05.2020)
Published in Hepatology communications (01.05.2020)
Get full text
Journal Article
PAS Kinase Drives Lipogenesis through SREBP-1 Maturation
Wu, Xiaoying, Romero, Donna, Swiatek, Wojciech I., Dorweiler, Irene, Kikani, Chintan K., Sabic, Hana, Zweifel, Ben S., McKearn, John, Blitzer, Jeremy T., Nickols, G. Allen, Rutter, Jared
Published in Cell reports (Cambridge) (10.07.2014)
Published in Cell reports (Cambridge) (10.07.2014)
Get full text
Journal Article
Regulation of Collagenase-3 and Osteocalcin Gene Expression by Collagen and Osteopontin in Differentiating MC3T3-E1 Cells
D'Alonzo, Richard C., Kowalski, Aaron J., Denhardt, David T., Nickols, G. Allen, Partridge, Nicola C.
Published in The Journal of biological chemistry (05.07.2002)
Published in The Journal of biological chemistry (05.07.2002)
Get full text
Journal Article
Reduction in Atherosclerotic Lesion Size in Pigs by αVβ3 Inhibitors Is Associated With Inhibition of Insulin-Like Growth Factor-I–Mediated Signaling
Nichols, Timothy C, Laney, Tracey du, Zheng, Bo, Bellinger, Dwight A, Nickols, G Allen, Engleman, Wayne, Clemmons, David R
Published in Circulation research (26.11.1999)
Published in Circulation research (26.11.1999)
Get full text
Journal Article
Bone cell function, regulation, and communication: a role for nitric oxide
Collin-Osdoby, P, Nickols, G A, Osdoby, P
Published in Journal of cellular biochemistry (01.03.1995)
Published in Journal of cellular biochemistry (01.03.1995)
Get more information
Journal Article
Effect of dietary calcium supplementation on blood pressure and calciotropic hormones in mineralocorticoid-salt hypertension
DiPette, D J, Greilich, P E, Nickols, G A, Graham, G A, Green, A, Cooper, C W, Holland, O B
Published in Journal of hypertension (01.06.1990)
Published in Journal of hypertension (01.06.1990)
Get more information
Journal Article
Synthesis of pyrazoles and isoxazoles as potent αvβ3 receptor antagonists
PENNING, Thomas D, KHILEVICH, Albert, HANNEKE, Melanie L, KEENE, Jeffery L, KLOVER, Jon A, NICKOLS, G. Allen, NICKOLS, Maureen A, RADER, Randall K, SETTLE, Steven L, SHANNON, Kristen E, STEININGER, Christina N, WESTLIN, Marisa M, CHEN, Barbara B, WESTLIN, William F, RUSSELL, Mark A, BOYS, Mark L, YAPING WANG, DUFFIN, Tiffany, ENGLEMAN, V. Wayne, FINN, Mary Beth, FREEMAN, Sandra K
Published in Bioorganic & medicinal chemistry letters (15.06.2006)
Published in Bioorganic & medicinal chemistry letters (15.06.2006)
Get full text
Journal Article
Selective inhibition of the inducible nitric oxide synthase by aminoguanidine
Misko, Thomas P., Moore, William M., Kasten, Thomas P., Nickols, G.Allen, Corbett, John A., Tilton, Ronald G., McDaniel, Michael L., Williamson, Joseph R., Currie, Mark G.
Published in European journal of pharmacology (16.03.1993)
Published in European journal of pharmacology (16.03.1993)
Get full text
Journal Article
Convergent, parallel synthesis of a series of β-substituted 1,2,4-oxadiazole butanoic acids as potent and selective αvβ3 receptor antagonists
BOYS, Mark L, SCHRETZMAN, Lori A, STENMARK, Heather G, HONGWEI WU, SPANGLER, Dale P, CLARE, Michael, DESAI, Bipin N, KHANNA, Ish K, NGUYEN, Maria N, DUFFIN, Tiffany, WAYNE ENGLEMAN, V, FINN, Mary Beth, CHANDRAKUMAR, Nizal S, FREEMAN, Sandra K, HANNEKE, Melanie L, KEENE, Jeffery L, KLOVER, Jon A, NICKOLS, G. Allen, NICKOLS, Maureen A, STEININGER, Christina N, WESTLIN, Marisa, WESTLIN, William, YU, Yi X, TOLLEFSON, Michael B, YAPING WANG, DALTON, Christopher R, NORRING, Sarah A, MOHLER, Scott B, DOWNS, Victoria L, PENNING, Thomas D, RUSSELL, Mark A, WENDT, John A, CHEN, Barbara B
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Get full text
Journal Article
Potentiation of Osteoclast Bone-Resorption Activity by Inhibition of Nitric Oxide Synthase
Kasten, Thomas P., Collin-Osdoby, Patricia, Patel, Niraj, Osdoby, Philip, Krukowski, Marilyn, Misko, Thomas P., Settle, Steven L., Currie, Mark G., Nickols, G. Allen
Published in Proceedings of the National Academy of Sciences - PNAS (26.04.1994)
Published in Proceedings of the National Academy of Sciences - PNAS (26.04.1994)
Get full text
Journal Article
Synthesis of 2,5-thiazole butanoic acids as potent and selective αvβ3 integrin receptor antagonists with improved oral pharmacokinetic properties
WENDT, John A, HONGWEI WU, KEENE, Jeffery L, WAYNE ENGLEMAN, V, FREEMAN, Sandra K, HANNEKE, Melanie L, SHANNON, Kristen E, NICKOLS, Maureen A, STEININGER, Christina N, WESTLIN, Marissa, KLOVER, Jon A, WESTLIN, William, STENMARK, Heather G, NICKOLS, G. Allen, RUSSELL, Mark A, BOYS, Mark L, DOWNS, Victoria L, PENNING, Thomas D, CHEN, Barbara B, YAPING WANG, DUFFIN, Tiffany, FINN, Mary Beth
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Get full text
Journal Article
Synthesis of pyrazoles and isoxazoles as potent alpha(v)beta3 receptor antagonists
Penning, Thomas D, Khilevich, Albert, Chen, Barbara B, Russell, Mark A, Boys, Mark L, Wang, Yaping, Duffin, Tiffany, Engleman, V Wayne, Finn, Mary Beth, Freeman, Sandra K, Hanneke, Melanie L, Keene, Jeffery L, Klover, Jon A, Nickols, G Allen, Nickols, Maureen A, Rader, Randall K, Settle, Steven L, Shannon, Kristen E, Steininger, Christina N, Westlin, Marisa M, Westlin, William F
Published in Bioorganic & medicinal chemistry letters (15.06.2006)
Get full text
Published in Bioorganic & medicinal chemistry letters (15.06.2006)
Journal Article
Synthesis of 2,5-thiazole butanoic acids as potent and selective alpha(v)beta3 integrin receptor antagonists with improved oral pharmacokinetic properties
Wendt, John A, Wu, Hongwei, Stenmark, Heather G, Boys, Mark L, Downs, Victoria L, Penning, Thomas D, Chen, Barbara B, Wang, Yaping, Duffin, Tiffany, Finn, Mary Beth, Keene, Jeffery L, Engleman, V Wayne, Freeman, Sandra K, Hanneke, Melanie L, Shannon, Kristen E, Nickols, Maureen A, Steininger, Christina N, Westlin, Marissa, Klover, Jon A, Westlin, William, Nickols, G Allen, Russell, Mark A
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Get full text
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Journal Article
Synthesis of pyrazoles and isoxazoles as potent α vβ 3 receptor antagonists
Penning, Thomas D., Khilevich, Albert, Chen, Barbara B., Russell, Mark A., Boys, Mark L., Wang, Yaping, Duffin, Tiffany, Engleman, V. Wayne, Finn, Mary Beth, Freeman, Sandra K., Hanneke, Melanie L., Keene, Jeffery L., Klover, Jon A., Nickols, G. Allen, Nickols, Maureen A., Rader, Randall K., Settle, Steven L., Shannon, Kristen E., Steininger, Christina N., Westlin, Marisa M., Westlin, William F.
Published in Bioorganic & medicinal chemistry letters (2006)
Published in Bioorganic & medicinal chemistry letters (2006)
Get full text
Journal Article
Synthesis of 2,5-thiazole butanoic acids as potent and selective α vβ 3 integrin receptor antagonists with improved oral pharmacokinetic properties
Wendt, John A., Wu, Hongwei, Stenmark, Heather G., Boys, Mark L., Downs, Victoria L., Penning, Thomas D., Chen, Barbara B., Wang, Yaping, Duffin, Tiffany, Finn, Mary Beth, Keene, Jeffery L., Engleman, V. Wayne, Freeman, Sandra K., Hanneke, Melanie L., Shannon, Kristen E., Nickols, Maureen A., Steininger, Christina N., Westlin, Marissa, Klover, Jon A., Westlin, William, Nickols, G. Allen, Russell, Mark A.
Published in Bioorganic & medicinal chemistry letters (2006)
Published in Bioorganic & medicinal chemistry letters (2006)
Get full text
Journal Article
Synthesis of cinnamic acids and related isosteres as potent and selective alpha v beta 3 receptor antagonists
Penning, Thomas D, Russell, Mark A, Chen, Barbara B, Chen, Helen Y, Desai, Bipin N, Docter, Stephen H, Edwards, David J, Gesicki, Glen J, Liang, Chi-Dean, Malecha, James W, Yu, Stella S, Engleman, V Wayne, Freeman, Sandra K, Hanneke, Melanie L, Shannon, Kristen E, Westlin, Marisa M, Nickols, G Allen
Published in Bioorganic & medicinal chemistry letters (22.03.2004)
Published in Bioorganic & medicinal chemistry letters (22.03.2004)
Get full text
Journal Article
Synthesis of cinnamic acids and related isosteres as potent and selective αvβ3 receptor antagonists
Penning, Thomas D., Russell, Mark A., Chen, Barbara B., Chen, Helen Y., Desai, Bipin N., Docter, Stephen H., Edwards, David J., Gesicki, Glen J., Liang, Chi-Dean, Malecha, James W., Yu, Stella S., Engleman, V.Wayne, Freeman, Sandra K., Hanneke, Melanie L., Shannon, Kristen E., Westlin, Marisa M., Nickols, G.Allen
Published in Bioorganic & medicinal chemistry letters (22.03.2004)
Published in Bioorganic & medicinal chemistry letters (22.03.2004)
Get full text
Journal Article
Convergent, parallel synthesis of a series of beta-substituted 1,2,4-oxadiazole butanoic acids as potent and selective alpha(v)beta3 receptor antagonists
Boys, Mark L, Schretzman, Lori A, Chandrakumar, Nizal S, Tollefson, Michael B, Mohler, Scott B, Downs, Victoria L, Penning, Thomas D, Russell, Mark A, Wendt, John A, Chen, Barbara B, Stenmark, Heather G, Wu, Hongwei, Spangler, Dale P, Clare, Michael, Desai, Bipin N, Khanna, Ish K, Nguyen, Maria N, Duffin, Tiffany, Engleman, V Wayne, Finn, Mary Beth, Freeman, Sandra K, Hanneke, Melanie L, Keene, Jeffery L, Klover, Jon A, Nickols, G Allen, Nickols, Maureen A, Steininger, Christina N, Westlin, Marisa, Westlin, William, Yu, Yi X, Wang, Yaping, Dalton, Christopher R, Norring, Sarah A
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Get full text
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Journal Article