Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease
Zhou, Yingyue, Song, Wilbur M., Andhey, Prabhakar S., Swain, Amanda, Levy, Tyler, Miller, Kelly R., Poliani, Pietro L., Cominelli, Manuela, Grover, Shikha, Gilfillan, Susan, Cella, Marina, Ulland, Tyler K., Zaitsev, Konstantin, Miyashita, Akinori, Ikeuchi, Takeshi, Sainouchi, Makoto, Kakita, Akiyoshi, Bennett, David A., Schneider, Julie A., Nichols, Michael R., Beausoleil, Sean A., Ulrich, Jason D., Holtzman, David M., Artyomov, Maxim N., Colonna, Marco
Published in Nature medicine (01.01.2020)
Published in Nature medicine (01.01.2020)
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Journal Article
Evolutionarily Conserved Principles Predict 3D Chromatin Organization
Rowley, M. Jordan, Nichols, Michael H., Lyu, Xiaowen, Ando-Kuri, Masami, Rivera, I. Sarahi M., Hermetz, Karen, Wang, Ping, Ruan, Yijun, Corces, Victor G.
Published in Molecular cell (07.09.2017)
Published in Molecular cell (07.09.2017)
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Journal Article
Disentangling aggregation-prone proteins: a new method for isolating α-synuclein species: An Editorial Highlight for "A simple, versatile and robust centrifugation-based filtration protocol for the isolation and quantification of α-synuclein monomers, oligomers and fibrils: Towards improving experimental reproducibility in α-synuclein research" on page 103
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Journal Article
The intricate biophysical puzzle of caspase-1 activation
Makoni, Nyasha J., Nichols, Michael R.
Published in Archives of biochemistry and biophysics (15.03.2021)
Published in Archives of biochemistry and biophysics (15.03.2021)
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Journal Article
A tethered-inchworm model of SMC DNA translocation
Nichols, Michael H., Corces, Victor G.
Published in Nature structural & molecular biology (01.10.2018)
Published in Nature structural & molecular biology (01.10.2018)
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Journal Article
Inflammatory mechanisms in neurodegeneration
Nichols, Michael R., St‐Pierre, Marie‐Kim, Wendeln, Ann‐Christin, Makoni, Nyasha J., Gouwens, Lisa K., Garrad, Evan C., Sohrabi, Mona, Neher, Jonas J., Tremblay, Marie‐Eve, Combs, Colin K.
Published in Journal of neurochemistry (01.06.2019)
Published in Journal of neurochemistry (01.06.2019)
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Journal Article
Analysis of Hi-C data using SIP effectively identifies loops in organisms from C. elegans to mammals
Rowley, M Jordan, Poulet, Axel, Nichols, Michael H, Bixler, Brianna J, Sanborn, Adrian L, Brouhard, Elizabeth A, Hermetz, Karen, Linsenbaum, Hannah, Csankovszki, Gyorgyi, Lieberman Aiden, Erez, Corces, Victor G
Published in Genome research (01.03.2020)
Published in Genome research (01.03.2020)
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Journal Article
A new class of monoclonal Aβ antibodies selectively targets and triggers deposition of Aβ protofibrils
Grover, Shikha, Pham, Thao, Jones, Anna, Sinobas‐Pereira, Cristina, Villoch Diaz Maurino, Marina, Garrad, Evan C., Makoni, Nyasha J., Parks, Antanisha, Domalewski, Ryan J., Riggio, Gabriel, An, Hannah, Chen, Kunhua, Nichols, Michael R.
Published in Journal of neurochemistry (01.06.2023)
Published in Journal of neurochemistry (01.06.2023)
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Journal Article
Aptamers as Reversible Sorting Ligands for Preparation of Cells in Their Native State
Gray, Bethany Powell, Requena, Martin D., Nichols, Michael D., Sullenger, Bruce A.
Published in Cell chemical biology (20.02.2020)
Published in Cell chemical biology (20.02.2020)
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Journal Article
Chromatin alternates between A and B compartments at kilobase scale for subgenic organization
Harris, Hannah L., Gu, Huiya, Olshansky, Moshe, Wang, Ailun, Farabella, Irene, Eliaz, Yossi, Kalluchi, Achyuth, Krishna, Akshay, Jacobs, Mozes, Cauer, Gesine, Pham, Melanie, Rao, Suhas S. P., Dudchenko, Olga, Omer, Arina, Mohajeri, Kiana, Kim, Sungjae, Nichols, Michael H., Davis, Eric S., Gkountaroulis, Dimos, Udupa, Devika, Aiden, Aviva Presser, Corces, Victor G., Phanstiel, Douglas H., Noble, William Stafford, Nir, Guy, Di Pierro, Michele, Seo, Jeong-Sun, Talkowski, Michael E., Aiden, Erez Lieberman, Rowley, M. Jordan
Published in Nature communications (06.06.2023)
Published in Nature communications (06.06.2023)
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Journal Article
Development of β-sheet structure in Aβ aggregation intermediates diminishes exposed hydrophobic surface area and enhances proinflammatory activity
Dhami, Kapur B., Karki, Sanjib, Parks, Antanisha, Nichols, Cameron G., Nichols, Michael R.
Published in Biochimica et biophysica acta. Proteins and proteomics (01.09.2022)
Published in Biochimica et biophysica acta. Proteins and proteomics (01.09.2022)
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Journal Article
An integrated -omics analysis of the epigenetic landscape of gene expression in human blood cells
Kennedy, Elizabeth M, Goehring, George N, Nichols, Michael H, Robins, Chloe, Mehta, Divya, Klengel, Torsten, Eskin, Eleazar, Smith, Alicia K, Conneely, Karen N
Published in BMC genomics (19.06.2018)
Published in BMC genomics (19.06.2018)
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Journal Article
Expression of NLRP3 inflammasome proteins in ExpiCHO‐S mammalian cells reveals oligomerization properties that are highly sensitive to solution conditions
Makoni, Nyasha J., Garrad, Evan C., Redzic, Adela, Nichols, Michael R.
Published in Biotechnology progress (01.07.2021)
Published in Biotechnology progress (01.07.2021)
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Journal Article
Amyloid-β42 protofibrils are internalized by microglia more extensively than monomers
Gouwens, Lisa K, Makoni, Nyasha J, Rogers, Victoria A, Nichols, Michael R
Published in Brain research (01.10.2016)
Published in Brain research (01.10.2016)
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Journal Article