PF-06463922 is a potent and selective next-generation ROS1/ALK inhibitor capable of blocking crizotinib-resistant ROS1 mutations
Zou, Helen Y., Li, Qiuhua, Engstrom, Lars D., West, Melissa, Appleman, Vicky, Wong, Katy A., McTigue, Michele, Deng, Ya-Li, Liu, Wei, Brooun, Alexei, Timofeevski, Sergei, McDonnell, Scott R. P., Jiang, Ping, Falk, Matthew D., Lappin, Patrick B., Affolter, Timothy, Nichols, Tim, Hu, Wenyue, Lam, Justine, Johnson, Ted W., Smeal, Tod, Charest, Al, Fantin, Valeria R.
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2015)
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Journal Article
Geospatial analysis of reported activity locations to identify sites for tuberculosis screening
Yuen, Courtney M., Brooks, Meredith B., Millones, Ana Karina, Acosta, Diana, Del Águila-Rojas, Erika, Campos, Hortencia, Farroñay, Sheyla, Morales, Giannina, Ramirez-Sandoval, Judith, Nichols, Tim C., Jimenez, Judith, Jenkins, Helen E., Lecca, Leonid
Published in Scientific reports (18.08.2022)
Published in Scientific reports (18.08.2022)
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Journal Article
Identifying barriers and facilitators to implementation of community-based tuberculosis active case finding with mobile X-ray units in Lima, Peru: a RE-AIM evaluation
Yuen, Courtney M, Puma, Daniela, Millones, Ana Karina, Galea, Jerome T, Tzelios, Christine, Calderon, Roger I, Brooks, Meredith B, Jimenez, Judith, Contreras, Carmen, Nichols, Tim C, Nicholson, Tom, Lecca, Leonid, Becerra, Mercedes C, Keshavjee, Salmaan
Published in BMJ open (07.07.2021)
Published in BMJ open (07.07.2021)
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Journal Article
Breaching the DNA damage checkpoint via PF-00477736, a novel small-molecule inhibitor of checkpoint kinase 1
Blasina, Alessandra, Hallin, Jill, Chen, Enhong, Arango, Maria Elena, Kraynov, Eugenia, Register, James, Grant, Stephan, Ninkovic, Sacha, Chen, Ping, Nichols, Tim, O'Connor, Patrick, Anderes, Kenna
Published in Molecular cancer therapeutics (01.08.2008)
Published in Molecular cancer therapeutics (01.08.2008)
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Journal Article
Exploring the impact of public health teams on alcohol premises licensing in England and Scotland (ExILEnS): procotol for a mixed methods natural experiment evaluation
Fitzgerald, Niamh, Egan, Matt, de Vocht, Frank, Angus, Colin, Nicholls, James, Shortt, Niamh, Nichols, Tim, Maani Hessari, Nason, McQuire, Cheryl, Purves, Richard, Critchlow, Nathan, Mohan, Andrea, Mahon, Laura, Sumpter, Colin, Bauld, Linda
Published in BMC medical research methodology (06.11.2018)
Published in BMC medical research methodology (06.11.2018)
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Journal Article
Study of the PDK1/AKT signaling pathway using selective PDK1 inhibitors, HCS, and enhanced biochemical assays
Hofler, Alexandra, Nichols, Tim, Grant, Stephan, Lingardo, Laura, Esposito, Edward A., Gridley, Scott, Murphy, Sean T., Kath, John C., Cronin, Ciarán N., Kraus, Michelle, Alton, Gordon, Xie, Zhi, Sutton, Scott, Gehring, Mike, Ermolieff, Jacques
Published in Analytical biochemistry (15.07.2011)
Published in Analytical biochemistry (15.07.2011)
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Journal Article
Dose-dependent effects of small-molecule antagonists on the genomic landscape of androgen receptor binding
Zhu, Zhou, Shi, Manli, Hu, Wenyue, Estrella, Heather, Engebretsen, Jon, Nichols, Tim, Briere, David, Hosea, Natilie, Los, Gerrit, Rejto, Paul A, Fanjul, Andrea
Published in BMC genomics (31.07.2012)
Published in BMC genomics (31.07.2012)
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Journal Article
Shear shock wave injury in vivo: High frame-rate ultrasound observation and histological assessment
Chandrasekaran, Sandhya, Santibanez, Francisco, Long, Tyler, Nichols, Tim, Kait, Jason, Bruegge, Ruth Vorder, ‘Dale’ Bass, Cameron R., Pinton, Gianmarco
Published in Journal of biomechanics (01.03.2024)
Published in Journal of biomechanics (01.03.2024)
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Journal Article
Measuring How Public Health Stakeholders Seek to Influence Alcohol Premises Licensing in England and Scotland: The Public Health Engagement In Alcohol Licensing (PHIAL) Measure
Fitzgerald, Niamh, Mohan, Andrea, Maani, Nason, Purves, Richard, de Vocht, Frank, Angus, Colin, Henney, Madeleine, Nicholls, James, Nichols, Tim, Crompton, Gemma, Mahon, Laura, McQuire, Cheryl, Shortt, Niamh, Bauld, Linda, Egan, Matt
Published in Journal of studies on alcohol and drugs (01.03.2023)
Published in Journal of studies on alcohol and drugs (01.03.2023)
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Journal Article
Pan-FGFR inhibition leads to blockade of FGF23 signaling, soft tissue mineralization, and cardiovascular dysfunction
Yanochko, Gina M, Vitsky, Allison, Heyen, Jonathan R, Hirakawa, Brad, Lam, Justine L, May, Jeff, Nichols, Tim, Sace, Frederick, Trajkovic, Dusko, Blasi, Eileen
Published in Toxicological sciences (01.10.2013)
Published in Toxicological sciences (01.10.2013)
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Journal Article
Abstract 2355: Palbociclib enhances the antitumor activity of taxanes by abrogating cell cycle checkpoints and alleviating hypoxia in squamous cell lung cancer
Cao, Joan, Zhu, Zhou, Wang, Hui, Nichols, Tim, Rosfjord, Edward, Hopf, Christine, Upeslacis, Erik, Rejto, Paul, Weinrich, Scott, Vanarsdale, Todd, Hardwick, James, Wei, Ping
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
[18F]FLT-PET Imaging Does Not Always Light Up Proliferating Tumor Cells
ZHANG, Cathy C, ZHENGMING YAN, FAHEY, Neeta R, CULLINANE, Carleen, SPILKER, Mary, ZASADNY, Kenneth, O'BRIEN, Peter, BUCKMAN, Dana, WONG, Anthony, CHRISTENSEN, James G, WENLIN LI, KUSZPIT, Kyle, PAINTER, Cory L, QIN ZHANG, LAPPIN, Patrick B, NICHOLS, Tim, LIRA, Maruja E, AFFOLTER, Timothy
Published in Clinical cancer research (01.03.2012)
Published in Clinical cancer research (01.03.2012)
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Journal Article
CDK4/6 Inhibition on Glucose and Pancreatic Beta Cell Homeostasis in Young and Aged Rats
Sacaan, Aida I, Thibault, Stephane, Hong, Miyoun, Kondegowda, Nagesha G, Nichols, Tim, Li, Rosemary, Rosselot, Carolina, Evering, Winston, Fenutria, Rafael, Vitsky, Allison, Brown, Thomas, Finkelstein, Martin, Garcia-Ocaña, Adolfo, Khan, Nasir, Stewart, Andrew F, Vasavada, Rupangi C
Published in Molecular cancer research (01.11.2017)
Published in Molecular cancer research (01.11.2017)
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Journal Article
Abstract 1697: Therapeutic targeting the NOTCH3 receptor with antibody drug conjugates
Geles, Kenneth G., Gao, Yijie, Sridharan, Latha, Giannakou, Andreas, Yamin, Ting-Ting, Golas, Jonathan, Lucas, Judy, Charati, Manoj, Li, Xiantang, Guffroy, Magali, Nichols, Tim, Wang, Kai, Follettie, Max, Maderna, Andreas, Tchistiakova, Lioudmila, Gerber, Hans-Peter, Sapra, Puja
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Applied User Research in Games
Pagulayan, Randy J, Gunn, Daniel V, Hagen, Jerome R, Hendersen, Deborah J. O, Kelley, Todd A, Phillips, Bruce C, Guajardo, J. J, Nichols, Tim A
Published in The Wiley Handbook of Human Computer Interaction (14.02.2018)
Published in The Wiley Handbook of Human Computer Interaction (14.02.2018)
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Book Chapter
Comparison of dynamic contrast‐enhanced MR, ultrasound and optical imaging modalities to evaluate the antiangiogenic effect of PF‐03084014 and sunitinib
Zhang, Cathy C., Yan, Zhengming, Giddabasappa, Anand, Lappin, Patrick B., Painter, Cory L., Zhang, Qin, Li, Gang, Goodman, James, Simmons, Brett, Pascual, Bernadette, Lee, Joseph, Levkoff, Ted, Nichols, Tim, Xie, Zhiyong
Published in Cancer medicine (Malden, MA) (01.06.2014)
Published in Cancer medicine (Malden, MA) (01.06.2014)
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Journal Article