Effect of the MDM2 antagonist RG7112 on the P53 pathway in patients with MDM2 -amplified, well-differentiated or dedifferentiated liposarcoma: an exploratory proof-of-mechanism study
Ray-Coquard, Isabelle, Dr, Blay, Jean-Yves, Prof, Italiano, Antoine, MD, Le Cesne, Axel, MD, Penel, Nicolas, MD, Zhi, Jianguo, PhD, Heil, Florian, PhD, Rueger, Ruediger, MD, Graves, Bradford, PhD, Ding, Meichun, PhD, Geho, David, MD, Middleton, Steven A, PhD, Vassilev, Lyubomir T, PhD, Nichols, Gwen L, MD, Bui, Binh Nguyen, MD
Published in The lancet oncology (01.11.2012)
Published in The lancet oncology (01.11.2012)
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Journal Article
Anti-spike antibody response to SARS-CoV-2 booster vaccination in patients with B cell-derived hematologic malignancies
Greenberger, Lee M., Saltzman, Larry A., Senefeld, Jonathon W., Johnson, Patrick W., DeGennaro, Louis J., Nichols, Gwen L.
Published in Cancer cell (11.10.2021)
Published in Cancer cell (11.10.2021)
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Journal Article
Activation of p53 by the MDM2 inhibitor RG7112 impairs thrombopoiesis
Iancu-Rubin, Camelia, Mosoyan, Goar, Glenn, Kelli, Gordon, Ronald E, Nichols, Gwen L, Hoffman, Ronald
Published in Experimental hematology (01.02.2014)
Published in Experimental hematology (01.02.2014)
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Phase I study of daily and weekly regimens of the orally administered MDM2 antagonist idasanutlin in patients with advanced tumors
Italiano, Antoine, Miller, Wilson H., Blay, Jean-Yves, Gietema, Jourik A., Bang, Yung-Jue, Mileshkin, Linda R., Hirte, Hal W., Higgins, Brian, Blotner, Steven, Nichols, Gwen L., Chen, Lin Chi, Petry, Claire, Yang, Qi Joy, Schmitt, Christophe, Jamois, Candice, Siu, Lillian L.
Published in Investigational new drugs (01.12.2021)
Published in Investigational new drugs (01.12.2021)
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Pre-clinical evaluation of the MDM2-p53 antagonist RG7388 alone and in combination with chemotherapy in neuroblastoma
Chen, Lindi, Rousseau, Raphaël F, Middleton, Steven A, Nichols, Gwen L, Newell, David R, Lunec, John, Tweddle, Deborah A
Published in Oncotarget (30.04.2015)
Published in Oncotarget (30.04.2015)
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Anti-spike T-cell and Antibody Responses to SARS-CoV-2 mRNA Vaccines in Patients with Hematologic Malignancies
Greenberger, Lee M, Saltzman, Larry A, Gruenbaum, Lore M, Xu, Jun, Reddy, Sneha T, Senefeld, Jonathon W, Johnson, Patrick W, Fields, Paul A, Sanders, Catherine, DeGennaro, Louis J, Nichols, Gwen L
Published in Blood cancer discovery (02.11.2022)
Published in Blood cancer discovery (02.11.2022)
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Journal Article
Unusual uterine recurrence of primary central nervous system lymphoma
Nichols, Gwen L, Jacobson, Caron A, Ferman, Debra, Lichtman, Stuart M
Published in Clinical advances in hematology & oncology (01.09.2006)
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Published in Clinical advances in hematology & oncology (01.09.2006)
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Sars-Cov-2 Antibody Levels in Blood Cancer Patients after a Third Sars-Cov-2 “Booster” Vaccination - Observational Data from the LLS National Registry
Greenberger, Lee M, Saltzman, Larry A, Senefeld, Jonathon W, Johnson, Patrick W, DeGennaro, Louis J, Nichols, Gwen L
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Abstract P161: Impaired serological response to SARS-CoV-2 mRNA vaccination in patients with hematologic malignancies
Greenberger, Lee M., Saltzman, Larry A., Senefeld, Jonathon W., Johnson, Patrick W., DeGennaro, Louis J., Nichols, Gwen L.
Published in Molecular cancer therapeutics (01.12.2021)
Published in Molecular cancer therapeutics (01.12.2021)
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Breakthrough COVID-19 Infections in Patients with Hematologic Malignancies during the Omicron (B.1.1.529) Surge: Data from the Patient-Reported Leukemia & Lymphoma Society National Registry
Reddy, Sneha T, Saltzman, Larry A, DeGennaro, Louis J, Nichols, Gwen L, Scott, Janaela, Senefeld, Jonathon W, Johnson, Patrick W, Greenberger, Lee M
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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ITCC-101/APAL2020D: A Randomized Phase 3 Trial of Fludarabine/Cytarabine/Gemtuzumab Ozogamycin with or without Venetoclax in Children with Relapsed Acute Myeloid Leukemia
Ishimaru, Sae, Gueguen, Gwenaëlle, Karol, Seth E., Bautista Sirvent, Francisco J., Ceolin, Valeria, Goemans, Bianca F., Bakker, Marlous, Laurenzio, Laura Di, Lukin, Jennifer, Van Tinteren, Harm, Sunkersett, Gauri B., Onishi, Maika, Unnebrink, Kristina, Reinhardt, Dirk, Nichols, Gwen L, Kolb, E. Anders, Zwaan, C. Michel
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Feasibility and Preliminary Findings of a Novel, Patient-Centric Registry Model to Address Real-World Care Questions for Patients with Hematologic Malignancies
Cornew, Sophia C, Cardillo, Anthony B, DeGennaro, Louis J, Fields, Paul A, Gruenbaum, Lore M, Littleford, Hana, Martin, Richard L, Nichols, Gwen L, Nottke, Amanda C, O'Brien, Conner M, Reddy, Sneha T, Rosenbaum, Rhonda, Saltzman, Larry A, Sanders, Catherine, Xu, Jun, Greenberger, Lee M
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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