Relationship of Potency and Resilience to Drug Resistant Mutations for GW420867X Revealed by Crystal Structures of Inhibitor Complexes for Wild-Type, Leu100Ile, Lys101Glu, and Tyr188Cys Mutant HIV-1 Reverse Transcriptases
Ren, Jingshan, Nichols, Charles E, Chamberlain, Philip P, Weaver, Kurt L, Short, Steven A, Chan, Joseph H, Kleim, Jörg-Peter, Stammers, David K
Published in Journal of medicinal chemistry (17.05.2007)
Published in Journal of medicinal chemistry (17.05.2007)
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Journal Article
Structural insights into mechanisms of non‐nucleoside drug resistance for HIV‐1 reverse transcriptases mutated at codons 101 or 138
Ren, Jingshan, Nichols, Charles E., Stamp, Anna, Chamberlain, Phillip P., Ferris, Robert, Weaver, Kurt L., Short, Steven A., Stammers, David K.
Published in The FEBS journal (01.08.2006)
Published in The FEBS journal (01.08.2006)
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Journal Article
Structural and functional characterization of Salmonella enterica serovar Typhimurium YcbL: An unusual Type II glyoxalase
Stamp, Anna L., Owen, Paul, El Omari, Kamel, Nichols, Charles E., Lockyer, Michael, Lamb, Heather K., Charles, Ian G., Hawkins, Alastair R., Stammers, David K.
Published in Protein science (01.10.2010)
Published in Protein science (01.10.2010)
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Journal Article
Structures of S. aureus thymidylate kinase reveal an atypical active site configuration and an intermediate conformational state upon substrate binding
Kotaka, Masayo, Dhaliwal, Balvinder, Ren, Jingshan, Nichols, Charles E., Angell, Richard, Lockyer, Michael, Hawkins, Alastair R., Stammers, David K.
Published in Protein science (01.04.2006)
Published in Protein science (01.04.2006)
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Journal Article
Crystal structure of CC3 (TIP30): implications for its role as a tumor suppressor
El Omari, Kamel, Bird, Louise E, Nichols, Charles E, Ren, Jingshan, Stammers, David K
Published in The Journal of biological chemistry (06.05.2005)
Published in The Journal of biological chemistry (06.05.2005)
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Journal Article
Crystallographic studies of shikimate binding and induced conformational changes in Mycobacterium tuberculosis shikimate kinase
Dhaliwal, Balvinder, Nichols, Charles E., Ren, Jingshan, Lockyer, Michael, Charles, Ian, Hawkins, Alastair R., Stammers, David K.
Published in FEBS letters (10.09.2004)
Published in FEBS letters (10.09.2004)
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Journal Article
Crystal Structure of CC3 (TIP30)
El Omari, Kamel, Bird, Louise E., Nichols, Charles E., Ren, Jingshan, Stammers, David K.
Published in The Journal of biological chemistry (06.05.2005)
Published in The Journal of biological chemistry (06.05.2005)
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Journal Article
The structure of NMB1585, a MarR-family regulator from Neisseria meningitidis
Nichols, Charles E., Sainsbury, Sarah, Ren, Jingshan, Walter, Thomas S., Verma, Anil, Stammers, David K., Saunders, Nigel J., Owens, Raymond J.
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.03.2009)
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.03.2009)
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Journal Article
EMBEDDED PRIVATE SCALE OUT NETWORK
NICHOLS CHARLES E, HOLT KEITH, EL BATAL MOHAMAD, DELANEY WILLIAM PATRICK, DEKONING RODNEY A
Year of Publication 17.12.2010
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Year of Publication 17.12.2010
Patent
Structure of the PII signal transduction protein of Neisseria meningitidis at 1.85 Å resolution
Nichols, Charles E., Sainsbury, Sarah, Berrow, Nick S., Alderton, David, Saunders, Nigel J., Stammers, David K., Owens, Raymond J.
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.06.2006)
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.06.2006)
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Journal Article
Balanced, opportunistic multicore I/O scheduling from non-SMP applications
Humlicek, Don, Nichols, Charles E, Banerjee, Arindam, Gitchell, Anthony D, Diao, Yulu, Terrill, Scott
Year of Publication 03.11.2020
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Year of Publication 03.11.2020
Patent
Balanced, Opportunistic Multicore I/O Scheduling From Non-SMP Applications
Humlicek, Don, Nichols, Charles E, Banerjee, Arindam, Gitchell, Anthony D, Diao, Yulu, Terrill, Scott
Year of Publication 26.04.2018
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Year of Publication 26.04.2018
Patent
Methods and structure for near-live reprogramming of firmware in storage systems using a hypervisor
HILL REXFORD A, NICHOLS CHARLES E, LOGAN JOHN G, SNIDER TIMOTHY R, JESS MARTIN
Year of Publication 08.07.2014
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Year of Publication 08.07.2014
Patent