An Assessment of Drug-Drug Interactions: The Effect of Desvenlafaxine and Duloxetine on the Pharmacokinetics of the CYP2D6 Probe Desipramine in Healthy Subjects
PATRONEVA, Albena, CONNOLLY, Sandra M, FATATO, Penny, PEDERSEN, Ron, QIN JIANG, PAUL, Jeffrey, GUICO-PABIA, Christine, ISLER, Jennifer A, BURCZYNSKI, Michael E, NICHOLS, Alice I
Published in Drug metabolism and disposition (01.12.2008)
Published in Drug metabolism and disposition (01.12.2008)
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An Open-Label, Single-Dose, Parallel-Group Study of the Effects of Chronic Hepatic Impairment on the Safety and Pharmacokinetics of Desvenlafaxine
Baird-Bellaire, Susan, PhD, Behrle, Jessica A., MS, Parker, Vernon D., RPh, PhD, Patat, Alain, MD, Paul, Jeffrey, PhD, Nichols, Alice I., PhD
Published in Clinical therapeutics (01.06.2013)
Published in Clinical therapeutics (01.06.2013)
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Cytochrome P450 2D6 phenoconversion is common in patients being treated for depression: implications for personalized medicine
Preskorn, Sheldon H, Kane, Cecelia P, Lobello, Kasia, Nichols, Alice I, Fayyad, Rana, Buckley, Gina, Focht, Kristen, Guico-Pabia, Christine J
Published in The journal of clinical psychiatry (01.06.2013)
Published in The journal of clinical psychiatry (01.06.2013)
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Cytochrome P450 2D6 phenotype predicts antidepressant efficacy of venlafaxine: a secondary analysis of 4 studies in major depressive disorder
Lobello, Kasia W, Preskorn, Sheldon H, Guico-Pabia, Christine J, Jiang, Qin, Paul, Jeffrey, Nichols, Alice I, Patroneva, Albena, Ninan, Philip T
Published in The journal of clinical psychiatry (01.11.2010)
Published in The journal of clinical psychiatry (01.11.2010)
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Population Pharmacokinetics of Desvenlafaxine: Pharmacokinetics in Korean Versus US Populations
Nichols, Alice I., Liao, Sam, Abbas, Richat
Published in Clinical pharmacology in drug development (01.05.2018)
Published in Clinical pharmacology in drug development (01.05.2018)
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Open-label, 2-period sequential drug interaction study to evaluate the effect of a 100-mg dose of desvenlafaxine on the pharmacokinetics of tamoxifen when coadministered in healthy postmenopausal female subjects
Nichols, Alice I, Lubaczewski, Shannon, Liang, Yali, Matschke, Kyle, Braley, Gabriel, Ramey, Tanya
Published in International journal of clinical pharmacology and therapeutics (01.10.2014)
Published in International journal of clinical pharmacology and therapeutics (01.10.2014)
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Pharmacokinetics of Venlafaxine Extended Release 75 mg and Desvenlafaxine 50 mg in Healthy CYP2D6 Extensive and Poor Metabolizers: A Randomized, Open-Label, Two-Period, Parallel-Group, Crossover Study
Nichols, Alice I., Focht, Kristen, Jiang, Qin, Preskorn, Sheldon H., Kane, Cecelia P.
Published in Clinical drug investigation (01.03.2011)
Published in Clinical drug investigation (01.03.2011)
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Pharmacokinetics and Tolerability of Single-Ascending Doses of Desvenlafaxine Administered to Children and Adolescents with Major Depressive Disorder
Findling, Robert L, Groark, James, Tourian, Karen A, Ramaker, Sara A, Chiles, Deborah, Yang, Lingfeng, Nichols, Alice I
Published in Journal of child and adolescent psychopharmacology (01.12.2016)
Published in Journal of child and adolescent psychopharmacology (01.12.2016)
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Comparison of the pharmacokinetics of venlafaxine extended release and desvenlafaxine in extensive and poor cytochrome P450 2D6 metabolizers
Preskorn, Sheldon, Patroneva, Albena, Silman, Heather, Jiang, Qin, Isler, Jennifer A, Burczynski, Michael E, Ahmed, Saeeduddin, Paul, Jeffrey, Nichols, Alice I
Published in Journal of clinical psychopharmacology (01.02.2009)
Published in Journal of clinical psychopharmacology (01.02.2009)
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How the Probability and Potential Clinical Significance of Pharmacokinetically Mediated Drug-Drug Interactions Are Assessed in Drug Development: Desvenlafaxine as an Example
Macaluso, Matthew, Nichols, Alice I, Preskorn, Sheldon H
Published in Primary care companion for CNS disorders (2015)
Published in Primary care companion for CNS disorders (2015)
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The effects of desvenlafaxine and paroxetine on the pharmacokinetics of the cytochrome P450 2D6 substrate desipramine in healthy adults
Nichols, Alice I, Fatato, Penny, Shenouda, Magdy, Paul, Jeffrey, Isler, Jennifer A, Pedersen, Ronald D, Jiang, Qin, Ahmed, Saeeduddin, Patroneva, Albena
Published in Journal of clinical pharmacology (01.02.2009)
Published in Journal of clinical pharmacology (01.02.2009)
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Safety and Pharmacokinetics of an Intramuscular Monoclonal Antibody (SB 209763) against Respiratory Syncytial Virus (RSV) in Infants and Young Children at Risk for Severe RSV Disease
MEISSNER, H. C, GROOTHUIS, J. R, NICHOLS, A. I, JORKASKY, D. K, EVERITT, D. E, THOMPSON, K. A, RODRIGUEZ, W. J, WELLIVER, R. C, HOGG, G, GRAY, P. H, LOH, R, SIMOES, E. A. F, SLY, P, MILLER, A. K
Published in Antimicrobial Agents and Chemotherapy (01.05.1999)
Published in Antimicrobial Agents and Chemotherapy (01.05.1999)
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Desvenlafaxine for major depressive disorder: incremental clinical benefits from a second-generation serotonin-norepinephrine reuptake inhibitor
Nichols, Alice I, Tourian, Karen A, Tse, Susanna Y, Paul, Jeffrey
Published in Expert opinion on drug metabolism & toxicology (01.12.2010)
Published in Expert opinion on drug metabolism & toxicology (01.12.2010)
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