Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains
Arakhamia, Tamta, Lee, Christina E., Carlomagno, Yari, Kumar, Mukesh, Duong, Duc M., Wesseling, Hendrik, Kundinger, Sean R., Wang, Kevin, Williams, Dewight, DeTure, Michael, Dickson, Dennis W., Cook, Casey N., Seyfried, Nicholas T., Petrucelli, Leonard, Steen, Judith A., Fitzpatrick, Anthony W.P.
Published in Cell (20.02.2020)
Published in Cell (20.02.2020)
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Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease
Rangaraju, Srikant, Dammer, Eric B, Raza, Syed Ali, Rathakrishnan, Priyadharshini, Xiao, Hailian, Gao, Tianwen, Duong, Duc M, Pennington, Michael W, Lah, James J, Seyfried, Nicholas T, Levey, Allan I
Published in Molecular neurodegeneration (21.05.2018)
Published in Molecular neurodegeneration (21.05.2018)
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Evidence for brain glucose dysregulation in Alzheimer's disease
An, Yang, Varma, Vijay R., Varma, Sudhir, Casanova, Ramon, Dammer, Eric, Pletnikova, Olga, Chia, Chee W., Egan, Josephine M., Ferrucci, Luigi, Troncoso, Juan, Levey, Allan I., Lah, James, Seyfried, Nicholas T., Legido-Quigley, Cristina, O'Brien, Richard, Thambisetty, Madhav
Published in Alzheimer's & dementia (01.03.2018)
Published in Alzheimer's & dementia (01.03.2018)
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Glutamate Dehydrogenase 1 Signals through Antioxidant Glutathione Peroxidase 1 to Regulate Redox Homeostasis and Tumor Growth
Jin, Lingtao, Li, Dan, Alesi, Gina N., Fan, Jun, Kang, Hee-Bum, Lu, Zhou, Boggon, Titus J., Jin, Peng, Yi, Hong, Wright, Elizabeth R., Duong, Duc, Seyfried, Nicholas T., Egnatchik, Robert, DeBerardinis, Ralph J., Magliocca, Kelly R., He, Chuan, Arellano, Martha L., Khoury, Hanna J., Shin, Dong M., Khuri, Fadlo R., Kang, Sumin
Published in Cancer cell (09.02.2015)
Published in Cancer cell (09.02.2015)
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TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD
Chou, Ching-Chieh, Zhang, Yi, Umoh, Mfon E., Vaughan, Spencer W., Lorenzini, Ileana, Liu, Feilin, Sayegh, Melissa, Donlin-Asp, Paul G., Chen, Yu Han, Duong, Duc M., Seyfried, Nicholas T., Powers, Maureen A., Kukar, Thomas, Hales, Chadwick M., Gearing, Marla, Cairns, Nigel J., Boylan, Kevin B., Dickson, Dennis W., Rademakers, Rosa, Zhang, Yong-Jie, Petrucelli, Leonard, Sattler, Rita, Zarnescu, Daniela C., Glass, Jonathan D., Rossoll, Wilfried
Published in Nature neuroscience (01.02.2018)
Published in Nature neuroscience (01.02.2018)
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Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer’s disease
Zhang, Zhentao, Song, Mingke, Liu, Xia, Su Kang, Seong, Duong, Duc M., Seyfried, Nicholas T., Cao, Xuebing, Cheng, Liming, Sun, Yi E., Ping Yu, Shan, Jia, Jianping, Levey, Allan I., Ye, Keqiang
Published in Nature communications (09.11.2015)
Published in Nature communications (09.11.2015)
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Quantitative Proteomics Reveals the Function of Unconventional Ubiquitin Chains in Proteasomal Degradation
Xu, Ping, Duong, Duc M., Seyfried, Nicholas T., Cheng, Dongmei, Xie, Yang, Robert, Jessica, Rush, John, Hochstrasser, Mark, Finley, Daniel, Peng, Junmin
Published in Cell (03.04.2009)
Published in Cell (03.04.2009)
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Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age
Wingo, Aliza P., Dammer, Eric B., Breen, Michael S., Logsdon, Benjamin A., Duong, Duc M., Troncosco, Juan C., Thambisetty, Madhav, Beach, Thomas G., Serrano, Geidy E., Reiman, Eric M., Caselli, Richard J., Lah, James J., Seyfried, Nicholas T., Levey, Allan I., Wingo, Thomas S.
Published in Nature communications (08.04.2019)
Published in Nature communications (08.04.2019)
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Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease
Johnson, Erik C B, Dammer, Eric B, Duong, Duc M, Yin, Luming, Thambisetty, Madhav, Troncoso, Juan C, Lah, James J, Levey, Allan I, Seyfried, Nicholas T
Published in Molecular neurodegeneration (04.10.2018)
Published in Molecular neurodegeneration (04.10.2018)
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Shared mechanisms across the major psychiatric and neurodegenerative diseases
Wingo, Thomas S., Liu, Yue, Gerasimov, Ekaterina S., Vattathil, Selina M., Wynne, Meghan E., Liu, Jiaqi, Lori, Adriana, Faundez, Victor, Bennett, David A., Seyfried, Nicholas T., Levey, Allan I., Wingo, Aliza P.
Published in Nature communications (26.07.2022)
Published in Nature communications (26.07.2022)
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Brain proteome-wide association study implicates novel proteins in depression pathogenesis
Wingo, Thomas S., Liu, Yue, Gerasimov, Ekaterina S., Gockley, Jake, Logsdon, Benjamin A., Duong, Duc M., Dammer, Eric B., Lori, Adriana, Kim, Paul J., Ressler, Kerry J., Beach, Thomas G., Reiman, Eric M., Epstein, Michael P., De Jager, Philip L., Lah, James J., Bennett, David A., Seyfried, Nicholas T., Levey, Allan I., Wingo, Aliza P.
Published in Nature neuroscience (01.06.2021)
Published in Nature neuroscience (01.06.2021)
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Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer’s Disease
Hsieh, Yi-Chen, Guo, Caiwei, Yalamanchili, Hari K., Abreha, Measho, Al-Ouran, Rami, Li, Yarong, Dammer, Eric B., Lah, James J., Levey, Allan I., Bennett, David A., De Jager, Philip L., Seyfried, Nicholas T., Liu, Zhandong, Shulman, Joshua M.
Published in Cell reports (Cambridge) (08.10.2019)
Published in Cell reports (Cambridge) (08.10.2019)
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Stress Induces p38 MAPK-Mediated Phosphorylation and Inhibition of Drosha-Dependent Cell Survival
Yang, Qian, Li, Wenming, She, Hua, Dou, Juan, Duong, Duc M., Du, Yuhong, Yang, Shao-Hua, Seyfried, Nicholas T., Fu, Haian, Gao, Guodong, Mao, Zixu
Published in Molecular cell (19.02.2015)
Published in Molecular cell (19.02.2015)
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A proteomic network approach across the ALS‐FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain
Umoh, Mfon E, Dammer, Eric B, Dai, Jingting, Duong, Duc M, Lah, James J, Levey, Allan I, Gearing, Marla, Glass, Jonathan D, Seyfried, Nicholas T
Published in EMBO molecular medicine (01.01.2018)
Published in EMBO molecular medicine (01.01.2018)
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Global quantitative analysis of the human brain proteome in Alzheimer’s and Parkinson’s Disease
Ping, Lingyan, Duong, Duc M., Yin, Luming, Gearing, Marla, Lah, James J., Levey, Allan I., Seyfried, Nicholas T.
Published in Scientific data (13.03.2018)
Published in Scientific data (13.03.2018)
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A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer’s Disease
Seyfried, Nicholas T., Dammer, Eric B., Swarup, Vivek, Nandakumar, Divya, Duong, Duc M., Yin, Luming, Deng, Qiudong, Nguyen, Tram, Hales, Chadwick M., Wingo, Thomas, Glass, Jonathan, Gearing, Marla, Thambisetty, Madhav, Troncoso, Juan C., Geschwind, Daniel H., Lah, James J., Levey, Allan I.
Published in Cell systems (25.01.2017)
Published in Cell systems (25.01.2017)
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Quantitative Analysis of the Brain Ubiquitylome in Alzheimer's Disease
Abreha, Measho H., Dammer, Eric B., Ping, Lingyan, Zhang, Tian, Duong, Duc M., Gearing, Marla, Lah, James J., Levey, Allan I., Seyfried, Nicholas T.
Published in Proteomics (Weinheim) (01.10.2018)
Published in Proteomics (Weinheim) (01.10.2018)
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Differential Phagocytic Properties of CD45low Microglia and CD45high Brain Mononuclear Phagocytes—Activation and Age-Related Effects
Rangaraju, Srikant, Raza, Syed Ali, Li, Noel Xiang’An, Betarbet, Ranjita, Dammer, Eric B., Duong, Duc, Lah, James J., Seyfried, Nicholas T., Levey, Allan I.
Published in Frontiers in immunology (02.03.2018)
Published in Frontiers in immunology (02.03.2018)
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Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain
Rayaprolu, Sruti, Bitarafan, Sara, Santiago, Juliet V., Betarbet, Ranjita, Sunna, Sydney, Cheng, Lihong, Xiao, Hailian, Nelson, Ruth S., Kumar, Prateek, Bagchi, Pritha, Duong, Duc M., Goettemoeller, Annie M., Oláh, Viktor János, Rowan, Matt, Levey, Allan I., Wood, Levi B., Seyfried, Nicholas T., Rangaraju, Srikant
Published in Nature communications (25.05.2022)
Published in Nature communications (25.05.2022)
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Multi-platform proteomic analysis of Alzheimer's disease cerebrospinal fluid and plasma reveals network biomarkers associated with proteostasis and the matrisome
Dammer, Eric B, Ping, Lingyan, Duong, Duc M, Modeste, Erica S, Seyfried, Nicholas T, Lah, James J, Levey, Allan I, Johnson, Erik C B
Published in Alzheimer's research & therapy (17.11.2022)
Published in Alzheimer's research & therapy (17.11.2022)
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