De novo-designed transmembrane domains tune engineered receptor functions
Elazar, Assaf, Chandler, Nicholas J, Davey, Ashleigh S, Weinstein, Jonathan Y, Nguyen, Julie V, Trenker, Raphael, Cross, Ryan S, Jenkins, Misty R, Call, Melissa J, Call, Matthew E, Fleishman, Sarel J
Published in eLife (04.05.2022)
Published in eLife (04.05.2022)
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Journal Article
De-novo designed transmembrane polypeptides and their uses in cellular immunotherapy
Sarel FLEISHMAN, Nicholas J. CHANDLER, Melissa J. CALL, Assaf ELAZAR, Jonathan Y. WEINSTEIN, Matthew E. CALL
Year of Publication 01.12.2021
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Year of Publication 01.12.2021
Patent
De novo designed receptor transmembrane domains enhance CAR-T cell cytotoxicity and attenuate cytokine release
Assaf Elazar, Chandler, Nicholas J, Davey, Ashleigh S, Weinstein, Jonathan Y, Nguyen, Julie V, Trenker, Raphael, Jenkins, Misty R, Call, Melissa J, Call, Matthew E, Fleishman, Sarel J
Published in bioRxiv (26.07.2020)
Published in bioRxiv (26.07.2020)
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Paper