Search Results - "Nicholas B. Lydon" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia

Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia

by Druker, Brian J, Talpaz, Moshe, Resta, Debra J, Peng, Bin, Buchdunger, Elisabeth, Ford, John M, Lydon, Nicholas B, Kantarjian, Hagop, Capdeville, Renaud, Ohno-Jones, Sayuri, Sawyers, Charles L
Published in The New England journal of medicine (05.04.2001)

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Journal Article

Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

by Druker, B J, Tamura, S, Buchdunger, E, Ohno, S, Segal, G M, Fanning, S, Zimmermann, J, Lydon, N B
Published in Nature medicine (01.05.1996)

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Journal Article

Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia

Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia

by Druker, B J, Lydon, N B
Published in The Journal of clinical investigation (01.01.2000)

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Journal Article

Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors

Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors

by Elisabeth Buchdunger, Catherine L. Cioffi, Norman Law, David Stover, Sayuri Ohno-Jones, Brian J. Druker, Nicholas B. Lydon
Published in The Journal of pharmacology and experimental therapeutics (01.10.2000)

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Journal Article

Structures of staurosporine bound to CDK2 and cAPK – new tools for structure-based design of protein kinase inhibitors

Structures of staurosporine bound to CDK2 and cAPK – new tools for structure-based design of protein kinase inhibitors

by Toledo, Leticia M, Lydon, Nicholas B
Published in Structure (15.12.1997)

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Book Review Journal Article

Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative

Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative

by BUCHDUNGER, E, ZIMMERMANN, J, METT, H, MEYER, T, MÜLLER, M, DRUKER, B. J, LYDON, N. B
Published in Cancer research (Chicago, Ill.) (1996)

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Journal Article

Lessons learned from the development of imatinib

Lessons learned from the development of imatinib

by Lydon, Nicholas B, Druker, Brian J
Published in Leukemia research (01.05.2004)

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Journal Article

Potent and selective inhibitors of the Abl-kinase: phenylamino-pyrimidine (PAP) derivatives

Potent and selective inhibitors of the Abl-kinase: phenylamino-pyrimidine (PAP) derivatives

by Zimmermann, Jürg, Buchdunger, Elisabeth, Mett, Helmut, Meyer, Thomas, Lydon, Nicholas B.
Published in Bioorganic & medicinal chemistry letters (01.01.1997)

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Journal Article

Inhibition of the ABL Kinase Activity Blocks the Proliferation of BCR/ABL+Leukemic Cells and Induces Apoptosis

Inhibition of the ABL Kinase Activity Blocks the Proliferation of BCR/ABL+Leukemic Cells and Induces Apoptosis

by Gambacorti-Passerini, Carlo, le Coutre, Philipp, Mologni, Luca, Fanelli, Mirco, Bertazzoli, Carla, Marchesi, Edoardo, Di Nicola, Massimo, Biondi, Andrea, Corneo, Gian Marco, Belotti, Daniela, Pogliani, Enrico, Lydon, Nicholas B.
Published in Blood cells, molecules, & diseases (01.12.1997)

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Journal Article

Modulation of the SH2 Binding Specificity and Kinase Activity of Src by Tyrosine Phosphorylation within Its SH2 Domain (∗)

Modulation of the SH2 Binding Specificity and Kinase Activity of Src by Tyrosine Phosphorylation within Its SH2 Domain (∗)

by Stover, David R., Furet, Pascal, Lydon, Nicholas B.
Published in The Journal of biological chemistry (24.05.1996)

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Journal Article

Evidence for SH3 domain directed binding and phosphorylation of Sam68 by Src

Evidence for SH3 domain directed binding and phosphorylation of Sam68 by Src

by ZHIWEI SHEN, BATZER, A, KOEHLER, J. A, POLAKIS, P, SCHLESSINGER, J, LYDON, N. B, MORAN, M. F
Published in Oncogene (19.08.1999)

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Journal Article

Text of the Japan Prize Commemorative Lecture

Text of the Japan Prize Commemorative Lecture

by LYDON, Nicholas B.
Published in Gakujutsu no doukou (2012)

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Journal Article

CGP 57148, a Tyrosine Kinase Inhibitor, Inhibits the Growth of Cells Expressing BCR-ABL, TEL-ABL, and TEL-PDGFR Fusion Proteins

CGP 57148, a Tyrosine Kinase Inhibitor, Inhibits the Growth of Cells Expressing BCR-ABL, TEL-ABL, and TEL-PDGFR Fusion Proteins

by Carroll, Martin, Ohno-Jones, Sayuri, Tamura, Shu, Buchdunger, Elisabeth, Zimmermann, Jürg, Lydon, Nicholas B., Gilliland, D. Gary, Druker, Brian J.
Published in Blood (15.12.1997)

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Journal Article

CGP 57148, a Tyrosine Kinase Inhibitor, Inhibits the Growth of Cells Expressing BCR-ABL, TEL-ABL, and TEL-PDGFR Fusion Proteins

CGP 57148, a Tyrosine Kinase Inhibitor, Inhibits the Growth of Cells Expressing BCR-ABL, TEL-ABL, and TEL-PDGFR Fusion Proteins

by Carroll, Martin, Ohno-Jones, Sayuri, Tamura, Shu, Buchdunger, Elisabeth, Zimmermann, Jürg, Lydon, Nicholas B., Gilliland, D. Gary, Druker, Brian J.
Published in Blood (15.12.1997)

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Journal Article

The structure-based design of ATP-site directed protein kinase inhibitors

The structure-based design of ATP-site directed protein kinase inhibitors

by Toledo, L M, Lydon, N B, Elbaum, D
Published in Current medicinal chemistry (01.09.1999)

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Journal Article

Paeciloquinones A, B, C, D, E and F: New Potent Inhibitors of Protein Tyrosine Kinases Produced by Paecilomyces carneus: I. Taxonomy, Fermentation, Isolation and Biological Activity

Paeciloquinones A, B, C, D, E and F: New Potent Inhibitors of Protein Tyrosine Kinases Produced by Paecilomyces carneus: I. Taxonomy, Fermentation, Isolation and Biological Activity

by PETERSEN, FRANK, FREDENHAGEN, ANDREAS, METT, HELMUT, LYDON, NICHOLAS B., DELMENDO, RON, JENNY, HANS-BEAT, PETER, HEINRICH H.
Published in Journal of antibiotics (01.01.1995)

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Journal Article

Src Phosphorylation of the Epidermal Growth Factor Receptor at Novel Sites Mediates Receptor Interaction with Src and P85α(∗)

Src Phosphorylation of the Epidermal Growth Factor Receptor at Novel Sites Mediates Receptor Interaction with Src and P85α(∗)

by Stover, David R., Becker, Michael, Liebetanz, Janis, Lydon, Nicholas B.
Published in The Journal of biological chemistry (30.06.1995)

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Journal Article

Selective Inhibition of the Platelet-Derived Growth Factor Signal Transduction Pathway by a Protein-Tyrosine Kinase Inhibitor of the 2- Phenylaminopyrimidine Class

Selective Inhibition of the Platelet-Derived Growth Factor Signal Transduction Pathway by a Protein-Tyrosine Kinase Inhibitor of the 2- Phenylaminopyrimidine Class

by Buchdunger, Elisabeth, Zimmermann, Jurg, Mett, Helmut, Meyer, Thomas, Muller, Marcel, Regenass, Urs, Lydon, Nicholas B.
Published in Proceedings of the National Academy of Sciences - PNAS (28.03.1995)

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Journal Article

Phenylamino-pyrimidine (PAP) — derivatives: a new class of potent and highly selective PDGF-receptor autophosphorylation inhibitors

Phenylamino-pyrimidine (PAP) — derivatives: a new class of potent and highly selective PDGF-receptor autophosphorylation inhibitors

by Zimmermann, Jürg, Buchdunger, Elisabeth, Mett, Helmut, Meyer, Thomas, Lydon, Nicholas B., Traxler, Peter
Published in Bioorganic & medicinal chemistry letters (04.06.1996)

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Journal Article

Immunoglobulins and variants directed against pathogenic microbes

Immunoglobulins and variants directed against pathogenic microbes

by Lydon, Nicholas B
Year of Publication 05.06.2018

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Patent