Modelling the asthma phenotype: impact of cigarette smoke exposure
Belvisi, Maria G, Baker, Katie, Malloy, Nicole, Raemdonck, Kristof, Dekkak, Bilel, Pieper, Michael, Nials, Anthony T, Birrell, Mark A
Published in Respiratory research (10.05.2018)
Published in Respiratory research (10.05.2018)
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Journal Article
In vivo characterization of GSK256066, a high-affinity inhaled phosphodiesterase 4 inhibitor
Nials, Anthony T, Tralau-Stewart, Cathy J, Gascoigne, Michele H, Ball, Douglas I, Ranshaw, Lisa E, Knowles, Richard G
Published in The Journal of pharmacology and experimental therapeutics (01.04.2011)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2011)
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Journal Article
GSK256066, an exceptionally high-affinity and selective inhibitor of phosphodiesterase 4 suitable for administration by inhalation: in vitro, kinetic, and in vivo characterization
Tralau-Stewart, Cathy J, Williamson, Richard A, Nials, Anthony T, Gascoigne, Michele, Dawson, John, Hart, Graham J, Angell, Anthony D R, Solanke, Yemisi E, Lucas, Fiona S, Wiseman, Joanne, Ward, Peter, Ranshaw, Lisa E, Knowles, Richard G
Published in The Journal of pharmacology and experimental therapeutics (01.04.2011)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2011)
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Journal Article
The Identification of a Novel Phosphodiesterase 4 Inhibitor, 1-Ethyl-5-{5-[(4-methyl-1-piperazinyl)methyl]-1,3,4-oxadiazol-2-yl}-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-b]pyridin-4-amine (EPPA-1), with Improved Therapeutic Index using Pica Feeding in Rats as a Measure of Emetogenicity
Davis, T Gregg, Peterson, John J, Kou, Jen-Pyng, Capper-Spudich, Elizabeth A, Ball, Doug, Nials, Anthony T, Wiseman, Joanne, Solanke, Yemisi E, Lucas, Fiona S, Williamson, Richard A, Ferrari, Livia, Wren, Paul, Knowles, Richard G, Barnette, Mary S, Podolin, Patricia L
Published in The Journal of pharmacology and experimental therapeutics (01.09.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2009)
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Journal Article
EP4 receptor as a new target for bronchodilator therapy
Buckley, James, Birrell, Mark A, Maher, Sarah A, Nials, Anthony T, Clarke, Deborah L, Belvisi, Maria G
Published in Thorax (01.12.2011)
Published in Thorax (01.12.2011)
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Journal Article
Route of Administration Affects Corticosteroid Sensitivity of a Combined Ovalbumin and Lipopolysaccharide Model of Asthma Exacerbation in Guinea Pigs
Lowe, Alexander P P, Thomas, Rhian S, Nials, Anthony T, Kidd, Emma J, Broadley, Kenneth J, Ford, William R
Published in The Journal of pharmacology and experimental therapeutics (01.08.2017)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2017)
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Journal Article
A comparison of antiasthma drugs between acute and chronic ovalbumin-challenged guinea-pig models of asthma
Evans, Rhys L, Nials, Anthony T, Knowles, Richard G, Kidd, Emma J, Ford, William R, Broadley, Kenneth J
Published in Pulmonary pharmacology & therapeutics (01.12.2012)
Published in Pulmonary pharmacology & therapeutics (01.12.2012)
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Journal Article
Adjustment of sensitisation and challenge protocols restores functional and inflammatory responses to ovalbumin in guinea-pigs
Lowe, Alexander P.P., Broadley, Kenneth J., Nials, Anthony T., Ford, William R., Kidd, Emma J.
Published in Journal of pharmacological and toxicological methods (01.03.2015)
Published in Journal of pharmacological and toxicological methods (01.03.2015)
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Journal Article
Pulmonary edema measured by MRI correlates with late-phase response to allergen challenge
Evans, Rhys L., Changani, Kumar K., Hotee, Sarah, Pindoria, Kashmira, Campbell, Simon, Nials, Anthony T., Ford, William R., Broadley, Kenneth J., Kidd, Emma J.
Published in Experimental lung research (01.05.2015)
Published in Experimental lung research (01.05.2015)
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Journal Article
The Identification of a Novel Phosphodiesterase 4 Inhibitor, 1-Ethyl-5-{5-[(4-methyl-1-piperazinyl)methyl]-1,3,4-oxadiazol-2-yl}- N -(tetrahydro-2 H -pyran-4-yl)-1 H -pyrazolo[3,4- b ]pyridin-4-amine (EPPA-1), with Improved Therapeutic Index using Pica Feeding in Rats as a Measure of Emetogenicity
Davis, T. Gregg, Peterson, John J., Kou, Jen-Pyng, Capper-Spudich, Elizabeth A., Ball, Doug, Nials, Anthony T., Wiseman, Joanne, Solanke, Yemisi E., Lucas, Fiona S., Williamson, Richard A., Ferrari, Livia, Wren, Paul, Knowles, Richard G., Barnette, Mary S., Podolin, Patricia L.
Published in The Journal of pharmacology and experimental therapeutics (01.09.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2009)
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Journal Article
Formoterol on airway smooth muscle and human lung mast cells: a comparison with salbutamol and salmeterol
Nials, Anthony T., Ball, Douglas I., Butchers, Peter R., Coleman, Robert A., Humbles, Alison A., Johnson, Malcolm, Vardey, Christopher J.
Published in European journal of pharmacology (14.01.1994)
Published in European journal of pharmacology (14.01.1994)
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Journal Article
Investigations into factors determining the duration of action of the beta 2-adrenoceptor agonist, salmeterol
Nials, A T, Sumner, M J, Johnson, M, Coleman, R A
Published in British journal of pharmacology (01.02.1993)
Published in British journal of pharmacology (01.02.1993)
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Journal Article
The Potential Roles of Cytokines, IL-5 and IL-8, and Plasma Cortisol in the Anti-inflammatory Actions of Phosphodiesterase Inhibitors in Sensitized Guinea-pig Airways
Danahay, Henry, Broadley, Kenneth J., McCabe, Patrick J., Nials, Anthony T., Sanjar, Shahin
Published in Pulmonary pharmacology & therapeutics (01.10.1997)
Published in Pulmonary pharmacology & therapeutics (01.10.1997)
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Journal Article
A simple, rapid, and sensitive scintillation proximity assay for the determination of levels of guinea-pig interleukin-5 in bronchoalveolar lavage samples
Danahay, Henry, Broadley, Kenneth J., McCabe, Patrick J., Nials, Anthony T., Sanjar, Shahin
Published in Journal of pharmacological and toxicological methods (01.04.1997)
Published in Journal of pharmacological and toxicological methods (01.04.1997)
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