Synthesis of 4-Substituted Chlorophthalazines, Dihydrobenzoazepinediones, 2-Pyrazolylbenzoic Acid, and 2-Pyrazolylbenzohydrazide via 3-Substituted 3-Hydroxyisoindolin-1-ones
Nguyen, Hanh Nho, Cee, Victor J, Deak, Holly L, Du, Bingfan, Faber, Kathleen Panter, Gunaydin, Hakan, Hodous, Brian L, Hollis, Steven L, Krolikowski, Paul H, Olivieri, Philip R, Patel, Vinod F, Romero, Karina, Schenkel, Laurie B, Geuns-Meyer, Stephanie D
Published in Journal of organic chemistry (20.04.2012)
Published in Journal of organic chemistry (20.04.2012)
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A Palladium-Catalyzed Regiospecific Synthesis of N-Aryl Benzimidazoles
Zheng, Nan, Anderson, Kevin W., Huang, Xiaohua, Nguyen, Hanh Nho, Buchwald, Stephen L.
Published in Angewandte Chemie International Edition (01.01.2007)
Published in Angewandte Chemie International Edition (01.01.2007)
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Preclinical Evaluation of AMG 900, a Novel Potent and Highly Selective Pan-Aurora Kinase Inhibitor with Activity in Taxane-Resistant Tumor Cell Lines
PAYTON, Marc, BUSH, Tammy L, NHO NGUYEN, Hanh, OLIVIERI, Philip R, ROMERO, Karina, SCHENKEL, Laurie B, BAK, Annette, STANTON, Mary, DUSSAULT, Isabelle, PATEL, Vinod F, GEUNS-MEYER, Stephanie, RADINSKY, Robert, CHUNG, Grace, KENDALL, Richard L, ZIEGLER, Beth, EDEN, Patrick, MCELROY, Patricia, ROSS, Sandra, CEE, Victor J, DEAK, Holly L, HODOUS, Brian L
Published in Cancer research (Chicago, Ill.) (01.12.2010)
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Discovery of N‑(4-(3-(2-Aminopyrimidin-4-yl)pyridin-2-yloxy)phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine (AMG 900), A Highly Selective, Orally Bioavailable Inhibitor of Aurora Kinases with Activity against Multidrug-Resistant Cancer Cell Lines
Geuns-Meyer, Stephanie, Cee, Victor J, Deak, Holly L, Du, Bingfan, Hodous, Brian L, Nguyen, Hanh Nho, Olivieri, Philip R, Schenkel, Laurie B, Vaida, Karina R, Andrews, Paul, Bak, Annette, Be, Xuhai, Beltran, Pedro J, Bush, Tammy L, Chaves, Mary K, Chung, Grace, Dai, Yang, Eden, Patrick, Hanestad, Kelly, Huang, Liyue, Lin, Min-Hwa Jasmine, Tang, Jin, Ziegler, Beth, Radinsky, Robert, Kendall, Richard, Patel, Vinod F, Payton, Marc
Published in Journal of medicinal chemistry (09.07.2015)
Published in Journal of medicinal chemistry (09.07.2015)
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Identification of a Potent, State-Dependent Inhibitor of Nav1.7 with Oral Efficacy in the Formalin Model of Persistent Pain
Bregman, Howard, Berry, Loren, Buchanan, John L, Chen, April, Du, Bingfan, Feric, Elma, Hierl, Markus, Huang, Liyue, Immke, David, Janosky, Brett, Johnson, Danielle, Li, Xingwen, Ligutti, Joseph, Liu, Dong, Malmberg, Annika, Matson, David, McDermott, Jeff, Miu, Peter, Nguyen, Hanh Nho, Patel, Vinod F, Waldon, Daniel, Wilenkin, Ben, Zheng, Xiao Mei, Zou, Anruo, McDonough, Stefan I, DiMauro, Erin F
Published in Journal of medicinal chemistry (14.07.2011)
Published in Journal of medicinal chemistry (14.07.2011)
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Discovery and hit-to-lead optimization of pyrrolopyrimidines as potent, state-dependent Na(v)1.7 antagonists
Chakka, Nagasree, Bregman, Howie, Du, Bingfan, Nguyen, Hanh Nho, Buchanan, John L, Feric, Elma, Ligutti, Joseph, Liu, Dong, McDermott, Jeff S, Zou, Anruo, McDonough, Stefan I, Dimauro, Erin F
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
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The discovery of aminopyrazines as novel, potent Na(v)1.7 antagonists: hit-to-lead identification and SAR
Bregman, Howard, Nguyen, Hanh Nho, Feric, Elma, Ligutti, Joseph, Liu, Dong, McDermott, Jeff S, Wilenkin, Ben, Zou, Anruo, Huang, Liyue, Li, Xingwen, McDonough, Stefan I, Dimauro, Erin F
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
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Discovery and optimization of aminopyrimidinones as potent and state-dependent Nav1.7 antagonists
Nguyen, Hanh Nho, Bregman, Howie, Buchanan, John L., Du, Bingfan, Feric, Elma, Huang, Liyue, Li, Xingwen, Ligutti, Joseph, Liu, Dong, Malmberg, Annika B., Matson, David J., McDermott, Jeff S., Patel, Vinod F., Wilenkin, Ben, Zou, Anruo, McDonough, Stefan I., DiMauro, Erin F.
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
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Journal Article
Discovery and hit-to-lead optimization of pyrrolopyrimidines as potent, state-dependent Nav1.7 antagonists
Chakka, Nagasree, Bregman, Howie, Du, Bingfan, Nguyen, Hanh Nho, Buchanan, John L., Feric, Elma, Ligutti, Joseph, Liu, Dong, McDermott, Jeff S., Zou, Anruo, McDonough, Stefan I., DiMauro, Erin F.
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
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Journal Article
The discovery of aminopyrazines as novel, potent Nav1.7 antagonists: Hit-to-lead identification and SAR
Bregman, Howard, Nguyen, Hanh Nho, Feric, Elma, Ligutti, Joseph, Liu, Dong, McDermott, Jeff S., Wilenkin, Ben, Zou, Anruo, Huang, Liyue, Li, Xingwen, McDonough, Stefan I., DiMauro, Erin F.
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
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Discovery of the first selective, small-molecule GFRα2/3 inhibitors through DNA-encoded library technology
Johnson, Shea L., Missig, Galen, Wang, Minghua, Ouk, Kosalvisal, Gupta, Kushali, Nguyen, Hanh Nho, Toh, May Fern, Ho, Tammy Szu-Yu, Gray, David, Zhang, Hongjun, Choi-Sledeski, Yong Mi, Barberis, Claude, Stone, David J., Pin, Sokhom, Lim, Jongwon
Published in Bioorganic & medicinal chemistry letters (15.09.2024)
Published in Bioorganic & medicinal chemistry letters (15.09.2024)
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The discovery of benzoxazine sulfonamide inhibitors of NaV1.7: Tools that bridge efficacy and target engagement
La, Daniel S., Peterson, Emily A., Bode, Christiane, Boezio, Alessandro A., Bregman, Howard, Chu-Moyer, Margaret Y., Coats, James, DiMauro, Erin F., Dineen, Thomas A., Du, Bingfan, Gao, Hua, Graceffa, Russell, Gunaydin, Hakan, Guzman-Perez, Angel, Fremeau, Robert, Huang, Xin, Ilch, Christopher, Kornecook, Thomas J., Kreiman, Charles, Ligutti, Joseph, Jasmine Lin, Min-Hwa, McDermott, Jeff S., Marx, Isaac, Matson, David J., McDonough, Stefan I., Moyer, Bryan D., Nho Nguyen, Hanh, Taborn, Kristin, Yu, Violeta, Weiss, Matthew M.
Published in Bioorganic & medicinal chemistry letters (01.08.2017)
Published in Bioorganic & medicinal chemistry letters (01.08.2017)
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Journal Article
A Palladium-Catalyzed Regiospecific Synthesis of N-Aryl Benzimidazoles
Zheng, Nan, Anderson, Kevin W., Huang, Xiaohua, Nguyen, Hanh Nho, Buchwald, Stephen L.
Published in Angewandte Chemie (01.10.2007)
Published in Angewandte Chemie (01.10.2007)
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Journal Article
The discovery of benzoxazine sulfonamide inhibitors of Na V 1.7: Tools that bridge efficacy and target engagement
La, Daniel S, Peterson, Emily A, Bode, Christiane, Boezio, Alessandro A, Bregman, Howard, Chu-Moyer, Margaret Y, Coats, James, DiMauro, Erin F, Dineen, Thomas A, Du, Bingfan, Gao, Hua, Graceffa, Russell, Gunaydin, Hakan, Guzman-Perez, Angel, Fremeau, Jr, Robert, Huang, Xin, Ilch, Christopher, Kornecook, Thomas J, Kreiman, Charles, Ligutti, Joseph, Jasmine Lin, Min-Hwa, McDermott, Jeff S, Marx, Isaac, Matson, David J, McDonough, Stefan I, Moyer, Bryan D, Nho Nguyen, Hanh, Taborn, Kristin, Yu, Violeta, Weiss, Matthew M
Published in Bioorganic & medicinal chemistry letters (01.08.2017)
Published in Bioorganic & medicinal chemistry letters (01.08.2017)
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