The BIM deletion polymorphism: A paradigm of a permissive interaction between germline and acquired TKI resistance factors in chronic myeloid leukemia
Ko, Tun Kiat, Chin, Hui San, Chuah, Charles T H, Huang, John W J, Ng, King-Pan, Khaw, Seong Lin, Huang, David C S, Ong, S Tiong
Published in Oncotarget (19.01.2016)
Published in Oncotarget (19.01.2016)
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Journal Article
An integrative model of pathway convergence in genetically heterogeneous blast crisis chronic myeloid leukemia
Ko, Tun Kiat, Javed, Asif, Lee, Kian Leong, Pathiraja, Thushangi N., Liu, Xingliang, Malik, Simeen, Soh, Sheila Xinxuan, Heng, Xiu Ting, Takahashi, Naoto, Tan, Joanna H.J., Bhatia, Ravi, Khng, Alexis J., Chng, Wee-Joo, Sia, Yee Yen, Fruman, David A., Ng, King Pan, Chan, Zhu En, Xie, Kim Jiajing, Hoi, Qiangze, Chan, Cheryl Xueli, Teo, Audrey S.M., Velazquez Camacho, Oscar, Meah, Wee Yang, Khor, Chiea Chuen, Ong, Chin Thing J., Soon, Wei Jia W., Tan, Patrick, Ng, Pauline C., Chuah, Charles, Hillmer, Axel M., Ong, S. Tiong
Published in Blood (25.06.2020)
Published in Blood (25.06.2020)
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Journal Article
Physiologic hypoxia promotes maintenance of CML stem cells despite effective BCR-ABL1 inhibition
Ng, King Pan, Manjeri, Aditi, Lee, Kian Leong, Huang, Weijie, Tan, Soo Yong, Chuah, Charles T.H., Poellinger, Lorenz, Ong, S. Tiong
Published in Blood (22.05.2014)
Published in Blood (22.05.2014)
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Journal Article
The arginase inhibitor Nω-hydroxy-nor-arginine (nor-NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target
Ng, King Pan, Manjeri, Aditi, Lee, Lin Ming, Chan, Zhu En, Tan, Chin Yee, Tan, Qiancheng Darren, Majeed, A'Qilah, Lee, Kian Leong, Chuah, Charles, Suda, Toshio, Ong, S Tiong
Published in PloS one (11.10.2018)
Published in PloS one (11.10.2018)
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Journal Article
Multiple Aromatic Side Chains within a Disordered Structure Are Critical for Transcription and Transforming Activity of EWS Family Oncoproteins
Ng, King Pan, Potikyan, Gary, Savene, Rupert O. V., Denny, Christopher T., Uversky, Vladimir N., Lee, Kevin A. W.
Published in Proceedings of the National Academy of Sciences - PNAS (09.01.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (09.01.2007)
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Journal Article
Rapid production of clinical‐grade SARS‐CoV‐2 specific T cells
Leung, Wing, Soh, Teck Guan, Linn, Yeh Ching, Low, Jenny Guek‐Hong, Loh, Jiashen, Chan, Marieta, Chng, Wee Joo, Koh, Liang Piu, Poon, Michelle Li‐Mei, Ng, King Pan, Kuick, Chik Hong, Tan, Thuan Tong, Tan, Lip Kun, Seng, Michaela Su‐fern
Published in Advances in Cell and Gene Therapy (01.10.2020)
Published in Advances in Cell and Gene Therapy (01.10.2020)
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Journal Article
Web Resource
The RNA Pol II sub-complex hsRpb4/7 is required for viability of multiple human cell lines
Zhao, Yang, Li, Kim K. C., Ng, King Pan, Ng, Chi Ho, Lee, Kevin A. W.
Published in Protein & cell (01.11.2012)
Published in Protein & cell (01.11.2012)
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Journal Article
The BIM deletion polymorphism potentiates the survival of leukemia stem and progenitor cells and impairs response to targeted therapies
Yu, Mengge, Nah, Giselle Sek Suan, Krishnan, Vaidehi, Sulaimi, Fatin Nasha Bte, Ng, King Pan, Wang, Chuqi, Bhatt, Shruti, Chuah, Charles, Bergstrom, David E, Ong, S Tiong
Published in Leukemia (22.10.2024)
Published in Leukemia (22.10.2024)
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Journal Article
A phase I/II study of adoptive SARS-CoV-2-specific T cells in immunocompromised hosts with or at risk of severe COVID-19 infection
Seng, Michaela Su-fern, Ng, King Pan, Soh, Teck Guan, Tan, Thuan Tong, Chan, Marieta, Maiwald, Matthias, Tan, Lip Kun, Linn, Yeh Ching, Leung, Wing
Published in Cytotherapy (Oxford, England) (01.10.2024)
Published in Cytotherapy (Oxford, England) (01.10.2024)
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Journal Article
A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer
Ng, King Pan, Hillmer, Axel M, Chuah, Charles T H, Juan, Wen Chun, Ko, Tun Kiat, Teo, Audrey S M, Ariyaratne, Pramila N, Takahashi, Naoto, Sawada, Kenichi, Fei, Yao, Soh, Sheila, Lee, Wah Heng, Huang, John W J, Allen, John C, Woo, Xing Yi, Nagarajan, Niranjan, Kumar, Vikrant, Thalamuthu, Anbupalam, Poh, Wan Ting, Ang, Ai Leen, Mya, Hae Tha, How, Gee Fung, Yang, Li Yi, Koh, Liang Piu, Chowbay, Balram, Chang, Chia-Tien, Nadarajan, Veera S, Chng, Wee Joo, Than, Hein, Lim, Lay Cheng, Goh, Yeow Tee, Zhang, Shenli, Poh, Dianne, Tan, Patrick, Seet, Ju-Ee, Ang, Mei-Kim, Chau, Noan-Minh, Ng, Quan-Sing, Tan, Daniel S W, Soda, Manabu, Isobe, Kazutoshi, Nöthen, Markus M, Wong, Tien Y, Shahab, Atif, Ruan, Xiaoan, Cacheux-Rataboul, Valère, Sung, Wing-Kin, Tan, Eng Huat, Yatabe, Yasushi, Mano, Hiroyuki, Soo, Ross A, Chin, Tan Min, Lim, Wan-Teck, Ruan, Yijun, Ong, S Tiong
Published in Nature medicine (01.04.2012)
Published in Nature medicine (01.04.2012)
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Journal Article
Activation of NOTCH signaling impedes cell proliferation and survival in acute megakaryoblastic leukemia
Ong, Kelly Ooi Kee, Mok, Michelle Meng Huang, Niibori-Nambu, Akiko, Du, Linsen, Yanagida, Masatoshi, Wang, Chelsia Qiuxia, Bahirvani, Avinash Govind, Chin, Desmond Wai Loon, Koh, Cai Ping, Ng, King Pan, Yamashita, Namiko, Jacob, Bindya, Yokomizo, Tomomasa, Takizawa, Hitoshi, Matsumura, Takayoshi, Suda, Toshio, Lau, Jie-ying Amelia, Tan, Tuan Zea, Mori, Seiichi, Yang, Henry, Iwasaki, Masayuki, Minami, Takashi, Asou, Norio, Sun, Qiao-Yang, Ding, Ling-Wen, Koeffler, H. Phillip, Tenen, Daniel G., Shimizu, Ritsuko, Yamamoto, Masayuki, Ito, Yoshiaki, Kham, Shirley Kow Yin, Yeoh, Allen Eng-Juh, Chng, Wee Joo, Osato, Motomi
Published in Experimental hematology (01.09.2024)
Published in Experimental hematology (01.09.2024)
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Journal Article
The BCL-2 Inhibitor ABT-199 Enhances Imatinib-Induced Cell Death In Chronic Phase CML Progenitors
Ko, Tun Kiat, Chuah, Charles, Huang, John, Ng, King-Pan, Ong, S. Tiong
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Journal Article
PRMT5 is required for the maintenance of genomic integrity in hematopoietic stem cells
Tan, Darren, Chin, Desmond, Li, Ying, Ng, King Pan, Nakamura-Ishizu, Ayako, Yang, Henry, Suda, Toshio
Published in EXPERIMENTAL HEMATOLOGY (01.09.2017)
Published in EXPERIMENTAL HEMATOLOGY (01.09.2017)
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Journal Article
Conference Proceeding
Physiologic Hypoxia Promotes Maintenance of CML Stem Cells Despite Effective BCR-ABL Inhibition
Ng, King-Pan, Lee, Kian Leong, Huang, Weijie, Poellinger, Lorenz, Chuah, Charles, Ong, Sin Tiong
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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Journal Article
The Genomic and Epigenomic Landscapes of Blast Crisis Transformation in Chronic Myeloid Leukemia
Ong, S. Tiong, Pathiraja, Thushangi, Javed, Asif, Soh, Xin Xuan Sheila, Malik, Simeen, Tan, Joanna H.J., Ko, Tun Kiat, Chuah, Charles, Takahashi, Naoto, Bhatia, Ravi, Ng, King Pan, Chng, Wee Joo, Tennakoon, Chandana, Hoi, Qiangze, Guan, Peiyong, Teo, Audrey S.M., Lee, Wah Heng, Tan, Patrick, Sung, Win Kin, Ng, Pauline, Hillmer, Axel
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Journal Article
Functional Analysis of the CML Blast Crisis Transcriptome and Epigenome Using Crispr-CAS9 and Pharmacologic Approaches
Ko, Tun Kiat, Soh, Xin Xuan Sheila, Yu, Willie, Winter, Peter S., Pathiraja, Thushangi, Javed, Asif, Malik, Simeen, Tan, Joanna H.J., Chuah, Charles, Takahashi, Naoto, Bhatia, Ravi, Chng, Wee Joo, Valent, Peter, Cerny-Reiterer, Sabine, Ng, King Pan, Tennakoon, Chandana, Hoi, Qiangze, Guan, Peiyong, Teo, Audrey S.M., Lee, Wah Heng, Tan, Patrick, Sung, Win Kin, Ng, Pauline, Hillmer, Axel, Wood, Kris C., Rozen, Steve, Ong, S. Tiong
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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